964 research outputs found
I. Novitzky, Die Ubereinstimmung der lnteressen im sowjetischen Zivilrecht
I. Novitzky, Die Ubereinstimmung der lnteressen im sowjetischen Zivilrecht. In: Revue internationale de droit comparé. Vol. 9 N°4, Octobre-décembre 1957. pp. 803-805
I. Novitzky, Die Ubereinstimmung der lnteressen im sowjetischen Zivilrecht
I. Novitzky, Die Ubereinstimmung der lnteressen im sowjetischen Zivilrecht. In: Revue internationale de droit comparé. Vol. 9 N°4, Octobre-décembre 1957. pp. 803-805
Myelodysplastic syndromes in children. A critical review of the clinical manifestations and management
The FAB group has defined myelodysplasia in adults but direct application of this categorization to children has been controversial. Consequently, to outline the natural history of the disease better we have retrospectively analysed case reports and series published in English between 1982 and 1996. This study also Included children with juvenile chronic myelomonocytic leukaemia (JCML) and monosomy 7 (Mo7). 340 patients were described in 27 publications. The mean presentation age was 5.91 (SD 5.04) years, and 34.9% were female. Constitutional alterations were described In 68 (20%) where refractory anemia (RA) and RA with excess of blasts (RAEB) predominated and were associated with a significantly longer survival. Among all patients progression to higher forms of MDS was noted in 61 (18%). Cytogenetic anomalies were detected in 59% of 227 children, and in 67 it was to Mo7. Amid those with Mo7, the clinical and laboratory characteristics as well as survival, closely followed their FAB type. Of the treatment options described, survival was significantly higher in those who underwent bone marrow transplant (BMT) (46.9%; P = 0.00021). Among children with JMML (CMML/JCML) not receiving a BMT, time to death was shortest in those best described as JCML (absence of constitutional and karyotypic derangement, thrombocytopenia and elevated Hb F). We conclude that children with constitutional abnormalities survive longer, Mo7 disorders are clinically and morphologically heterogeneous and should not be grouped into a single entity and that CMML and JCML may have biological differences. Finally, BMT remains the treatment of choice for those with primary MDS, as intensive chemotherapy is no better than supportive measures. Am. J. Hematol. 63:212-222, 2000. (C) 2000 Wiley-Liss, Inc
The Brain-Dead Organ Donor
Addressing all aspects of brain death and thoroughly detailing how a potential organ donor should be maintained to ensure maximum use of the organs and cells, The Brain-Dead Organ Donor: Pathophysiology and Management is a landmark addition to the literature. This first-of-its-kind, multidisciplinary volume will be of interest to a large section of the medical community. The first section of the book reviews the historical, medical, legal, and ethical aspects of brain death. That is followed by two chapters on the pathophysiology of brain death as investigated in small and large animal models. This includes a review of the many hormonal changes, including the neuroendocrine- adrenergic ‘storm’, that takes place during and following the induction of brain death, and how they impact metabolism. The next section of the book reviews various effects of brain death, namely its impact on thyroid function, the inflammatory response that develops, and those relating to innate immunity. The chapters relating to assessment and management of potential organ donors will be of interest to a very large group of transplant surgeons and physicians as well as critical care and neurocritical care physicians and nurses. Neurologists, endocrinologists, neurosurgeons, and pathologists will also be interested, especially in the more basic science sections on various aspects of brain-death and hormonal therapy. Organ procurement organizations and transplant coordinators worldwide will also be interested in this title. Other chapters will be of interest to medical historians, medico-legal experts, and ethicists.CONTENIDO: Introduction,
Dimitri Novitzky, David K. C. Cooper,
Pages 1-6 --
Historical Aspects of the Diagnosis of Death,
Félix Bacigalupo, Daniela A. Huerta Fernández,
Pages 7-11 --
The Determination of Brain Death,
Curtis M. Keller, Boris Chulpayev, Michael Hoffmann,
Pages 13-19 --
Legal Aspects of Brain Death and Organ Donorship,
Ricky T. Munoz, Mark D. Fox,
Pages 21-35 --
Ethical Issues in Organ Donation from Brain-Dead Donors,
Mark D. Fox, Ricky T. Munoz,
Pages 37-53 --
Pathophysiology of Brain Death in Small Animal Models,
Bernhard Floerchinger, Nicholas L. Tilney, Stefan G. Tullius,
Pages 55-64 --
Pathophysiology of Brain Death and Effects of Hormonal Therapy in Large Animal Models,
Dimitri Novitzky, Winston N. Wicomb, David K. C. Cooper,
Pages 65-90 --
The Efficacy of Thyroid Hormone Therapy in Brain-Dead Heart Donors: A Review of Thyroid Function in Health and Disease,
Lawrence E. Shapiro, Tatiana Baron,
Pages 91-105 --
The Inflammatory Response to Brain Death,
Anne Barklin, Christine Lodberg Hvas, Else Toennesen,
Pages 107-119 --
The Influence of Brain Death and Intensive Care Management on Donor Organs: Assessment of Inflammatory Markers,
Wayel Jassem, Susan V. Fuggle,
Pages 121-129 --
Brain Death-Induced Inflammation: Possible Role of the Cholinergic Anti-inflammatory Pathway,
Simone Hoeger, Benito A. Yard,
Pages 131-138 --
Innate Immunity and Injury During Brain Death: Opportunities for Intervention,
Marc A. Seelen, Henri G. D. Leuvenink, Rutger J. Ploeg,
Pages 139-145 --
Selection of the Brain-Dead Potential Organ Donor,
Kadiyala V. Ravindra, Keri E. Lunsford, Paul C. Kuo,
Pages 147-154 --
Infectious Disease Aspects of the Brain-Dead Potential Organ Donor,
Nicole M. Theodoropoulos, Michael G. Ison,
Pages 155-176 --
Malignancy in the Brain-Dead Organ Donor,
Michael A. Nalesnik, Ron Shapiro, Michael G. Ison,
Pages 177-189 --
Early Clinical Experience of Hormonal Therapy in the Brain-Dead Potential Organ Donor,
Dimitri Novitzky, Burcin Ekser, David K. C. Cooper,
Pages 191-207 --
Assessment, Monitoring, and Management of Brain-Dead Potential Organ Donors in the USA,
Demetrios Demetriades, Lydia Lam,
Pages 209-216 --
Assessment, Monitoring, and Management of Brain-Dead Potential Organ Donors in Europe,
Gabriel J. Echeverri, Bruno G. Gridelli,
Pages 217-235 --
Assessment, Monitoring, and Management of Brain-Dead Potential Organ Donors in Australia,
Peter S. Macdonald, Anders E. M. Aneman, Deepak Bhonagiri, Daryl A. Jones, Gerry O’Callaghan, Helen I. Opdam et al.,
Pages 237-249 -- Management of the Brain-Dead Organ Donor: Perspectives of the Transplant Coordinator,
Nicole T. Farina, David K. C. Cooper,
Pages 251-261 --
Surgical Aspects of Thoracic and Abdominal Organ Procurement from Brain-Dead Donors,
Michael J. Anstadt, Paul C. Kuo, Kadiyala V. Ravindra,
Pages 263-281 --
Impact of Brain Death on Storage of the Heart,
Winston N. Wicomb, David K. C. Cooper,
Pages 283-288 --
Impact of Brain Death on Abdominal Organs and Allograft Preservation Strategies,
Coney Bae, Anthony Watkins, Scot D. Henry, James V. Guarrera,
Pages 289-298 --
Functional Repair of Brain Death-Induced Injury,
Henri G. D. Leuvenink, Marc A. Seelen, Rutger J. Ploeg,
Pages 299-310 --
Functional Repair of Brain Death-Injured Donor Lungs,
Jonathan C. Yeung, Marcelo Cypel, Shaf Keshavjee,
Pages 311-320 --
Thyroid Hormone Therapy to the Recipient of a Heart from a Brain-Dead Donor,
Dimitri Novitzky, David K. C. Cooper,
Pages 321-331 --
Current and Potential Future Trends in the Management of the Brain-Dead Organ Donor,
Octavio E. Pajaro, James K. Kirklin,
Pages 333-341 --
Maximizing Utilization of the Potential Deceased Donor: The Challenge Continues,Eliezer Katz,Pages 343-35
Immune reconstitution post bone marrow transplantation
Bibliography: leaves 82-95.The aims of this project were therefore: to document the immune reconstitution following T-cell depleted bone marrow and peripheral blood stem cell transplantation and to compare this with the recovery following autologous grafts. to document the cell surface expression of CD95 in an attempt to comment on the role played by FAS mediated apoptosis in the post transplant immune deficiency
A Microscopic Study of Cancellous Bone at the Root Ends of Dead Teeth: The Results of Work Done in Collaboration with Frank E. Blaisdell, M.D., Associate Professor of Surgery, Director of the Laboratory of Surgical Pathology, Leland Stanford, Jr., University Medical College, San Francisco, California
n/
Gutenberg Album : Nagymesterük Gutenberg János születésének ... ötszázados évfordulója alkalmából kiadják a budapesti nyomdászok és betűöntők
"Sok bámulatos fölfedezés született meg Gutenberg óta. A vasut, a táviró, a telefon, a fonográf: megannyi imponáló alkotása az emberi kutató elmének. De Gutenberg egyszerü fölfedezését világhistóriai jelentőségben egyik sem közeliti meg. A nyomdászat az a kultura számára, a mi a testnek a levegő.
Systematic Study of Highly Asymmetric Systems Using π 0 , h ± and ϕ Production at PHENIX
Hematopoietic stem cell transplantation for adults with acute promyelocytic leukemia in the ATRA era: a survey of the European Cooperative Group for Blood and Marrow Transplantation
We performed a survey of the European Cooperative Group for Blood and Marrow Transplantation to analyze the outcome of 625 acute promyelocytic leukemia (APL) patients transplanted with auto- or allogeneic-hematopoietic stem cell transplantation (autoHSCT, alloHSCT) after 1993, in first (CR1) or in second complete remission (CR2). Leukemia-free survival (LFS) at 5 years in CR1 was 69% for 149 patients autografted and 68% for 144 patients allografted, whereas in CR2, LFS was 51% in 195 autoHSCT and 59% in 137 alloHSCT recipients, respectively. In the group of autoHSCT for CR1 (n=149), higher relapse incidence (RI) was associated with shorter time from diagnosis to transplant (<7.6 months); transplant-related mortality (TRM) was increased in older patients (>47 years), whereas for CR2, longer time from diagnosis to transplant (>18 months) was associated with increased LFS and decreased RI. In the alloHSCT group for CR1 (n=144), age (<33 years) was associated with increased LFS and decreased TRM and for CR2 (n=137), the use of mobilized peripheral blood stem cells was associated with decreased TRM. Female recipient, a female donor to male recipient and transplants performed before 1997 were associated with decreased RI. In conclusion, HSCT still appears to have a role in APL, especially for patients in CR2
Le problème financier russe. La dette publique de la Russie ...
Raffalovich, A. La dette publique de la Russie. Dette d'avant-guerre et opérations de crédit pendant la guerre.--Apostol, P. et Michelson, A. Les questions d'ordre international souleveÌes par le probleÌme de la dette russe.--Bernatzky, M. Le probleÌme de la circulation moneÌtaire de la Russie.--Novitzky, V. Le stock d'or de la Russie.Mode of access: Internet
- …
