1,522 research outputs found
Fabrication of nanoadjuvant with poly-ɛ-caprolactone (PCL) for developing a single-shot vaccine providing prolonged immunity [Corrigendum]
No full textPrashant CK, Bhat M, Srivastava SK, et al. Int J Nanomedicine. 2014;9:937–950.On page 937, the author affiliations have been listed incorrectly. The correct author list is as follows:Chandravilas Keshvan Prashant1Madhusudan Bhat2Sandeep Kumar Srivastava2Ankit Saxena3Manoj Kumar4Amar Singh3Mohammed Samim5Farhan Jalees Ahmad6Amit Kumar Dinda21Faculty of Engineering and Interdisciplinary Sciences, Jamia Hamdard, New Delhi, India; 2Department of Pathology, 3Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, New Delhi, India; 4Centre for Biomedical Engineering, Indian Institute of Technology, New Delhi, India; 5Department of Chemistry, Faculty of Science, Jamia Hamdard, New Delhi, India; 6Department of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard, New Delhi, IndiaRead the original articl
Paktongius Suzuki 1969
No full textGenus <i>Paktongius</i> Suzuki, 1969 <p> Type species: <i>Paktongius distinctus</i> Suzuki, 1969, by original designation.</p> <p> <i>Material examined.</i> ♀ (MHNG TH-09 /04) THAILAND, Krabi Prov., Khlong Thom Distr., Khao Pra —Bang Khram Wildlife Sanctuary (7°54’38”N, 99°16’40”E), 80 m, semi-evergreen rainforest, 2.vi.2009, <i>leg.</i> P. Schwendinger.</p>Published as part of <i>Klementz, Benjamin C. & Sharma, Prashant P., 2023, New species of Paktongius and convergent evolution of the gonyleptoid-like habitus in Southeast Asian Assamiidae (Opiliones: Laniatores), pp. 34-54 in Zootaxa 5389 (1)</i> on page 35, DOI: 10.11646/zootaxa.5389.1.2, <a href="http://zenodo.org/record/10404551">http://zenodo.org/record/10404551</a>
Defect controlled diffusion of lithium ions in Mn doped V2O5 for potential applications as cathode material
No full textWith a motivation to unravel the effect of cation (Mn) doping-induced modifications in structure, charge transfer resistance, and Li-ion diffusion in V2O5 a systematic study using X-ray diffraction (XRD), Raman Spectroscopy and electrochemical impedance spectroscopy (EIS) has been employed using three electrodes configuration. Structural investigations using XRD suggest the selective diffusion of Mn ion towards the c-axis at a low doping percentage. Raman spectroscopy suggests the shift in 994 cm-1 modes which substantiates the uniaxial diffusion of Mn ions. Nyquist plots show that interfacial charge transfer resistance is highest for the lowest doping i.e., 1% Mn-doped V2O5 and exhibits the lowest diffusion coefficient as compared to other doped V2O5 samples. Specific capacitance calculated from cyclic voltammetry is found to be highest for the 4% Mn-doped V2O5 sample. Moreover, diffusion of Lithium ions improves with an increase in doping concentration due to higher concentration of defects as evident from Δd/d and Nelson–Riley factor (NRF) for pure V2O5 and Mn-doped V2O5
Rock-Fluid Interaction During Low-Salinity Polymer Flow in Porous Media
No full textUsually, oil fields are developed over three stages. First is the primary oil recovery, where the natural underground pressure is used to drive the oil to the surface. Afterwards is the secondary oil recovery, usually by water flooding or gas injection. However, the water flood yields lower sweep efficiency in heterogeneous reservoirs, contrary to homogeneous reservoirs. Tertiary flooding methods are applied to increase the oil sweep efficiency, hereby improving the efficiency of the extraction process. These methods include injection of gas and chemical solutions. This study focusses on the polymer flooding method. Polymers are used to adjust the mobility ratio (M) between oil and the displacing fluid, where the viscosity of the displacing fluid is increased significantly. However, rock-fluid interaction might affect the viscosity of the polymer, which in turn affects the mobility ratio. A series of core flood experiments were conducted, where rock-fluid interaction likely affects the viscosity of the polymer. Hydrolyzed polyacrylamide (HPAM) is used as the polymer, which is injected in a sandstone core with brine. The produced fluids are analyzed afterwards, where its ion concentration, rheology, pH, and carbon content are measured. The results of the effluent analysis shows no change in viscosity compared to the injected polymer. There is however, a decrease in the divalent cations in the Low-salinity fluids, which can be explained by these cations getting stripped from the fluid at attaching to the rock surface. An increase in the effluent High-Salinity Brine is observed, which may be the cause of mechanical degradation, or by the influence of dissolved Ca2+ or Mg2+ cations due to leaching.Civil Engineerin
Meghalaya SPP.
No full textMEGHALAYA SPP. Other material examined: One female (ZSI) from Miao, Arunāchal Pradesh, Changlang District, India, 600 m a.s.l., collected 6 March 1990 by D. B. Bastawade (this is the specimen reported by Bastawade in 1992). One male (MHNG) from Khasi Hills, between Mawsynram and Balat, 16 km from Mawsynram, Meghālaya, India, 1000 m a.s.l., collected 27 October 1978 by C. Besuchet and I. Löbl. One male (MHNG) from Khasi Hills, above Shillong, North face, Meghālaya, India, 1850–1950 m a.s.l., collected 25 October 1978 by C. Besuchet and I. Löbl. One male (MHNG, MCZ DNA102051 ) from Tura trail (25°30′28′′N, 90°13′54′′E), Tura Peak, West Garo Hills District, Meghālaya, India, 650 m a.s.l., collected 14 October 2004 by G. Cuccodoro, C. Carlton, R. Leschen and D. Erne. This material may well correspond to four new species: the one from Miao known only from a female specimen, and the other three from Meghālaya, known by a single male each. We prefer to postpone the description of these new species until more material becomes available for study.Published as part of Giribet, Gonzalo, Sharma, Prashant P. & Bastawade, Deshbhushan B., 2007, A new genus and species of Cyphophthalmi (Arachnida: Opiliones) from the north-eastern states of India, pp. 663-670 in Zoological Journal of the Linnean Society 151 (4) on page 667, DOI: 10.1111/j.1096-3642.2007.00347.
Buffered Count-Min Sketch on SSD: Theory and Experiments
No full textFrequency estimation data structures such as the count-min sketch (CMS) have found numerous applications in databases, networking, computational biology and other domains. Many applications that use the count-min sketch process massive and rapidly evolving data sets. For data-intensive applications that aim to keep the overestimate error low, the count-min sketch becomes too large to store in available RAM and may have to migrate to external storage (e.g., SSD.) Due to the random-read/write nature of hash operations of the count-min sketch, simply placing it on SSD stifles the performance of time-critical applications, requiring about 4-6 random reads/writes to SSD per estimate (lookup) and update (insert) operation.
In this paper, we expand on the preliminary idea of the buffered count-min sketch (BCMS) {[Eydi et al., 2017]}, an SSD variant of the count-min sketch, that uses hash localization to scale efficiently out of RAM while keeping the total error bounded. We describe the design and implementation of the buffered count-min sketch, and empirically show that our implementation achieves 3.7 x-4.7 x speedup on update and 4.3 x speedup on estimate operations compared to the traditional count-min sketch on SSD.
Our design also offers an asymptotic improvement in the external-memory model over the original data structure: r random I/Os are reduced to 1 I/O for the estimate operation. For a data structure that uses k blocks on SSD, w as the word/counter size, r as the number of rows, M as the number of bits in the main memory, our data structure uses kwr/M amortized I/Os for updates, or, if kwr/M > 1, 1 I/O in the worst case. In typical scenarios, kwr/M is much smaller than 1. This is in contrast to O(r) I/Os incurred for each update in the original data structure.
Lastly, we mathematically show that for the buffered count-min sketch, the error rate does not substantially degrade over the traditional count-min sketch. Specifically, we prove that for any query q, our data structure provides the guarantee: Pr[Error(q) >= n epsilon (1+o(1))] <= delta + o(1), which, up to o(1) terms, is the same guarantee as that of a traditional count-min sketch
Orthetrum andamanicum Bedjanič & Kalkman & Subramanian 2020, sp. nov.
No full textOrthetrum andamanicum sp. nov. (Figs. 1, 2, 3–5, 6, 7, 8) Type material. Holotype: 1♂ (mature) (RMNH.INS.1152911)—[in smeared / discoloured ink on the poorly read- able original label: no stream nr. main road …], Chidiyatapu; South Andaman island, Andaman and Nicobar Islands, India; [app. N 11.51, E 92.71]; 08-xii-1998; [Prashant Mohanraj and K. Veenakumari leg.] (in RMNH). Paratype: 1♂ (mature)— Garacharma, Central Agricultural Research Institute - C.A.R.I. campus; South Anda- man island, Andaman and Nicobar Islands, India; alt. 70 m; N 11.610 6, E 92.7157; 28-vii-1996; Prashant Mohanraj and K. Veenakumari leg. (in RMNH) Etymology. The species epithet is an adjective; andamanicum, after the Andaman Islands, the island group from which the type locality and distribution of this new species is known.Published as part of Bedjanič, M., Kalkman, V. J. & Subramanian, K. A., 2020, A new species of Orthetrum Newman, 1833 (Odonata: Libellulidae) from the Andaman Islands, India, pp. 91-100 in Zootaxa 4779 (1) on page 92, DOI: 10.11646/zootaxa.4779.1.6, http://zenodo.org/record/383176
Systemic Cytokine Response predicts the Outcome of Patients from Mechanical Ventilation
No full textABSTRACT
Purpose
Despite the lifesaving potential, mechanical ventilation (MV) imposes a considerable amount of mechanical stress on the lung. Pulmonary and systemic cytokine release due to inflammatory process triggered by MV may give valuable information on patient outcome.
Materials and methods
Thirty patients aged >18 years with acute respiratory distress who required MV were enrolled for the study. Three milliliters of the venous blood was collected immediately after the initiation of MV and at 24 hours. Serum levels of interleukin (IL)-6, IL-8 and, tumor necrosis factor-α (TNF-α) were estimated using quantitative immunometric sandwich enzyme immunoassay technique. Based on their outcome from MV, they were divided into two groups: Survivors (group I) and nonsurvivors (group II).
Results
Serum levels of IL-6 and IL-8 significantly increased in group II (n=13) when compared with group I (n = 17) (p < 0.0001 and p < 0.001 respectively) at 24 hours of MV. However, TNF-α did not show any significant difference between the two groups. The IL-6 >111.9 pg/mL at 24 hours of MV increases the probability of mortality by factor 2.40. An increase of IL-6 by 1 pg/mL significantly increases the relative probability of mortality by a factor of 1.004 (95% CI, 1.0003–1.0078, p = 0.0001).
Conclusion
Estimating the levels of IL-6 and IL-8 at 24 hours of connecting the patient to MV will help in predicting the outcome of the patient.
How to cite this article
Prashant A, Vishwanath P, Kotekar N, Nataraj SM, Kuruvilla C, Nagalakshmi CS, Doddamani P. Systemic Cytokine Response predicts the Outcome of Patients from Mechanical Ventilation. Indian J Med Biochem 2017;21(1):5-10.
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Rodlike Bimetallic Ruthenium and Osmium Complexes Bridged by Phenylene Spacers. Synthesis, Electrochemistry, and Photophysics.
No full textIn the search for light-addressable nanosized compounds we have synthesized 10 dinuclear homometallic trisbipyridyl complexes of linear structure with the general formula [M(bpy)3-BL-M(bpy)3]4+ [M = Ru(II) or Os(II); BL = polyphenylenes (2, 3, 4, or 5 units) or indenofluorene; bpy = 2,2′-bipyridine]. By using a "chemistry on the complex" approach, different sizes of rodlike systems have been obtained with a length of 19.8 and 32.5 Å for the shortest and longest complex, respectively. For one of the ruthenium precursors, [RUbpy-ph2-Si(CH3) 3][PF6]2, single crystals were obtained by recrystallization from methanol. Their photophysical and electrochemical properties are reported. All the compounds are luminescent both at room and low temperature with long excited-state lifetimes due to an extended delocalization. Nanosecond transient absorption showed that the lowest excited state involves the chelating unit attached to the bridging ligand. Electrochemical data indicated that the first reduction is at a slightly more positive potential than for the reference complexes [M(bpy)3]2+ (M = Ru, Os). This result confirms that the best acceptor is the bipyridine moiety connected to the conjugated spacers. The role of the tilt angle between the phenylene units, in the two series of complexes, for the ground and excited states is discussed
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