435 research outputs found
High protein and low trypsin inhibitor varieties of full-fat soybeans in broiler chicken starter diets
No full textIn a randomized block design nutritional quality of 2 new varieties of full-fat soyabeans (SB) in broiler starter diets was evaluated. Protein sources were raw SB (39% crude protein (CP), 70 Trypsin Inhibitor Units (TIU) per g DM), autoclaved SB, autoclaved high protein (HP) SB, low trypsin inhibitor (LTI) (42 TIU/g DM) and commercially roasted SB. Diets were isonitrogenous and isoenergetic. Supplementing diets with 0.3% DL-methionine was also studied, as the antiproteolytic activity of the TI makes sulphur amino acids less available for growth. Mean body weight gain, feed conversion efficiency, DM and CP digestibilities and total carcass protein and energy content of the chickens fed HP, autoclaved or roasted SB were higher (P http://upei-resolver.asin-risa.ca?sid=SP:CABI&id=pmid:&id=&issn=0008-3984&isbn=&volume=73&issue=2&spage=401&pages=401-409&date=1993&title=Canadian%20Journal%20of%20Animal%20Science&atitle=High%20protein%20and%20low%20trypsin%20inhibitor%20varieties%20of%20full-fat%20soybeans%20in%20broiler%20chicken%20starter%20diets.&aulast=Chohan&pid=%3Cauthor%3EChohan%2c%20A%20K%3bHamilton%2c%20R%20M%20G%3bMcNiven%2c%20M%20A%3bMacLeod%2c%20J%20A%3C%2Fauthor%3E%3CAN%3E19931463725%3C%2FAN%3E%3CDT%3EJournal%20article%3C%2FDT%3
An integrated approach of artificial neural networks and polynomial chaos expansion for prediction and analysis of yield and environmental impact of oil shale retorting process under uncertainty
No full textShale oil reserves exploration is getting huge investments due to the depletion of conventional reserves. Computational methods have been used to realize optimum design and operation of shale oil and gas reserves exploration and processing. The uncertainty associated with the composition of shale reserves and operating conditions during processing put a challenge to the realization of high yield and mitigation of environmental impact. In the current work, machine learning (ML) based models are proposed for the estimation of the yield and environmental impact of the oil shale retorting process under uncertainty. An artificial uncertainty of 1% was inserted in feed composition and process conditions of an Aspen model of the process to generate data for the development of the ML models. Artificial Neural Network (ANN), Least Square Boosting (LSB), and Bagging techniques were compared to find the best ML model. ANN models, with the highest correlation coefficient of 0.995 and 0.999 for the oil yield and CO2 content respectively, are used as surrogates in a Polynomial Chaos Expansion (PCE) framework for the uncertainty analysis of the process. For 1% uncertainty in feed composition and process conditions, a mean absolute deviation of 0.319 and 0.580 was obtained for the oil yield and carbon dioxide emissions respectively. To find the hierarchy in the process inputs in terms of their effect on the oil yield and carbon dioxide emissions, the ANN model is used as a surrogate in sensitivity analysis through Sobol and Fourier Amplitude Sensitivity Test (FAST) indices. The most sensitive input variables were feed temperature and air molar flow rate. The proposed modeling framework will provide a base for future real-time monitoring and analysis of the oil shale retorting processes
Development of the Addiction Dimensions for Assessment and Personalised Treatment (ADAPT)
No full textAbstract not available.John Marsden , Brian Eastwood, Robert Ali, Pete Burkinshaw, Gagandeep Chohan, Alex Copello, Daniel Burn, Michael Kelleher, Luke Mitcheson, Steve Taylor, Nick Wilson, Chris Whiteley, Edward Da
N-Propyl-urea: The missing link
No full textThe title mol-ecule, C4H10N2O, is planar and its alkyl chain displays an all-trans configuration, which is typical for n-alkyl-urea structures. Pairs of mol-ecules are hydrogen bonded across crystallographic inversion centres [N⋯O = 2.962 (4) Å], with each O atom involved in two additional hydrogen bonds, linking adjacent urea molecules into chains along c [N⋯O = 2.924 (3) and 3.042 (3) Å]. Each chain is propagated by a c-glide operation and planes containing adjacent urea molecules inter-cept at an angle of 50.14 (9)°. © International Union of Crystallography 2007
Partial genetic deletion of neuregulin 1 and adolescent stress interact to alter NMDA receptor binding in the medial prefrontal cortex
No full textSchizophrenia is thought to arise due to a complex interaction between genetic and environmental factors during early neurodevelopment. We have recently shown that partial genetic deletion of the schizophrenia susceptibility gene neuregulin 1 (Nrg1) and adolescent stress interact to disturb sensorimotor gating, neuroendocrine activity and dendritic morphology in mice. Both stress and Nrg1 may have converging effects upon N-methyl-D-aspartate receptors (NMDARs) which are implicated in the pathogenesis of schizophrenia, sensorimotor gating and dendritic spine plasticity. Using an identical repeated restraint stress paradigm to our previous study, here we determined NMDAR binding across various brain regions in adolescent Nrg1 heterozygous (HET) and wild-type (WT) mice using [3H] MK-801 autoradiography. Repeated restraint stress increased NMDAR binding in the ventral part of the lateral septum (LSV) and the dentate gyrus (DG) of the hippocampus irrespective of genotype. Partial genetic deletion of Nrg1 interacted with adolescent stress to promote an altered pattern of NMDAR binding in the infralimbic (IL) subregion of the medial prefrontal cortex. In the IL, whilst stress tended to increase NMDAR binding in WT mice, it decreased binding in Nrg1 HET mice. However, in the DG, stress selectively increased the expression of NMDAR binding in Nrg1 HET mice but not WT mice. These results demonstrate a Nrg1-stress interaction during adolescence on NMDAR binding in the medial prefrontal cortex. © 2014 Chohan, Nguyen, Todd, Bennett, Callaghan and Arnol
Effect of different intracanal medicaments on the viability and survival of dental pulp stem cells
No full textBackground: Stem cells play an important role in the success of regenerative endodontic procedures. They are affected by the presence of medicaments that are used before the induction of bleeding or the creation of a scaffold for endodontic regeneration. This study examines the effects of different intracanal medicaments on the viability and survival of dental pulp stem cells at different doses and over different exposure times. Methods: Dental pulp stem cells were cultured from healthy third molar teeth using the long-term explant culture method and characterized using flow cytometry and exposed to different concentrations of calcium hydroxide, doxycycline, potassium iodide, triamcinolone, and glutaraldehyde, each ranging from 0 (control) to 1000 μg/mL. Exposure times were 6, 24, and 48 h. Cell viability was measured using the MTT assay, and apoptosis was measured using the Annexin V-binding assay. Results: All medicaments significantly reduced cell viability at different concentrations over different exposure times. Calcium hydroxide and triamcinolone favored cell viability at higher concentrations during all exposure times compared to other medicaments. The apoptosis assay showed a significant increase in cell death on exposure to doxycycline, potassium iodide, and glutaraldehyde. Conclusion: The intracanal medicaments examined in our study affected the viability of dental pulp stem cells in a time and dose-dependent manner. They also adversely affected the survival of dental pulp stem cells. Further studies are needed to better understand the effect of prolonged exposure to medicaments according to clinical protocols and their effect on the stemness of dental pulp stem cells
Quench Performance and Field Quality of the LHC Preseries Superconducting Dipoles
No full textThe preseries production of the LHC main superconducting dipoles is presently being tested at CERN. The foremost features of these magnets are: twin structure, six block two layer coils wound from 15.1 mm wide graded NbTi cables, 56 mm aperture, polyimide insulation and stainless steel collars. This paper reviews the main test results of magnets tested to day in both normal and superfluid helium. The results of the training performance, magnet protection, electrical integrity and the field quality are presented in terms of the specifications and expected performance of these magnets in the future accelerator
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