128 research outputs found
sj-docx-1-jop-10.1177_02698811221092509 – Supplemental material for Differences in social brain function in autism spectrum disorder are linked to the serotonin transporter: A randomised placebo-controlled single-dose crossover trial
No full textSupplemental material, sj-docx-1-jop-10.1177_02698811221092509 for Differences in social brain function in autism spectrum disorder are linked to the serotonin transporter: A randomised placebo-controlled single-dose crossover trial by Nichol ML Wong, Ottavia Dipasquale, Federico Turkheimer, James L Findon, Robert H Wichers, Mihail Dimitrov, Clodagh M Murphy, Vladimira Stoencheva, Dene M Robertson, Declan G Murphy, Eileen Daly and Grainne M McAlonan in Journal of Psychopharmacology</p
sj-docx-1-aut-10.1177_13623613221081343 – Supplemental material for Adults with autism spectrum disorder and the criminal justice system: An investigation of prevalence of contact with the criminal justice system, risk factors and sex differences in a specialist assessment service
No full textSupplemental material, sj-docx-1-aut-10.1177_13623613221081343 for Adults with autism spectrum disorder and the criminal justice system: An investigation of prevalence of contact with the criminal justice system, risk factors and sex differences in a specialist assessment service by Charlotte E Blackmore, Emma L Woodhouse, Nicola Gillan, Ellie Wilson, Karen L Ashwood, Vladimira Stoencheva, Alexandra Nolan, Grainne M McAlonan, Dene M Robertson, Susannah Whitwell, Quinton Deeley, Michael C Craig, Janneke Zinkstok, Rob Wichers, Debbie Spain, Ged Roberts, Declan GM Murphy, Clodagh M Murphy and Eileen Daly in Autism</p
Recent Advances in the Application, Design, and Operations & Maintenance of Aerated Treatment Wetlands
No full textInternational audienceThis paper outlines recent advances in the design, application, and operations and maintenance (O&M) of aerated treatment wetland systems as well as current research trends. We provide the first-ever comprehensive estimate of the number and geographical distribution of aerated treatment wetlands worldwide and review new developments in aerated wetland design and application. This paper also presents and discusses first-hand experiences and challenges with the O&M of full-scale aerated treatment wetland systems, which is an important aspect that is currently not well reported in the literature. Knowledge gaps and suggestions for future research on aerated treatment wetlands are provided
Beyond the COVID-19 Pandemic: Tips for Players and Athletes COVID-RECOVER
No full textFirst paragraph: The aim of this guidance is to provide a framework for athletes to cope, thrive and engage in personal growth during the current pandemic. The COVID-19 pandemic has likely led to wide-scale disruption of your sporting trajectories for 2020. This has included the cancellation or postponement of sporting events, limits to group training due to social distancing, restrictions on use of sporting facilities and loss of face-to-face access to coaches and support personnel. In the context of a threat to public health, arguably sports competition sinks into lesser importance, but for athletes like you, for whom sport is a fulltime job or major life goal, or for those who identify sports competition as a key part of their identity, it is important to share recommendations based on evidence and theory on how to support athletes and players through this time. The unprecedented situation means that evidence from similar or related contexts and relevant theories needs to be used to extrapolate to COVID-19 and all its challenges. Each of the guidelines below should be viewed like a menu to choose from and try, test and review, and be seen as a road to discovery instead of passive prescription of activities. Our team of practitioners and researchers have collated the knowledge below based on four premises: 1. Psychological Strengths: As a performer on the sporting stage, you have, in all likelihood, developed many skills and habits to support your on-field performance. Pre-performance routines for penalty taking, for example, may include relaxation and focusing components which aid emotional regulation. This can be also applied to help you cope in world outside of sport (i.e. outside the bubble). Awareness of your repertoire of psychological skills and the ability to use them across different contexts is highly important. 2. Resilience: The capacity to mobilise resources both in advance and after a major challenge, is developed through our sporting challenges. In the face of a trauma, it is likely that resilience is the default rather than the exception. As an athlete, you have the ability to respond in an optimistic way to major stressors and engage in post-traumatic growth. Further, you have successful experiences from memory to call upon on which By doing this, you build a firm foundation on which to build your beliefs that you have sufficient resources to cope with COVID-19. 3. Individual Responses: It is important to acknowledge that athletes in different sports and at different levels of competition have developed diverse sets of abilities and competencies. Dual-career athletes (e.g. student-athletes) may have invested much of their effort in their sport despite study or work commitments, and injured athletes may be over-identifying with their sport as a predictable response to injury, in both cases making these athletes very vulnerable to major stressors. 4. Perception of Control: Loss of control is a major source of anxiety in a pandemic (see Mansell, 2020). Developing autonomy and a sense of control is a key part to feeling safe and secure. With COVID-19, the new habits that could help protect you such as physical isolation, hand hygiene, and avoiding touching your face can help you gain control in an uncertain world. And finding new ways to exercise, to work and to interact can open up a world of exciting possibilities. Athletes have shown an ability to develop positive habits and maintain self-control, skills transferable to meeting the present challenging circumstances
Avoiding the 'twilight zone': Recommendations for the transition of services from adolescence to adulthood for young people with ADHD
No full textAttention deficit hyperactivity disorder (ADHD) is a common childhood disorder that frequently persists into adulthood. However, in the UK, there is a paucity of adult services available for the increasing number of young people with ADHD who are now graduating from child services. Furthermore, there is limited research investigating the transition of young people with ADHD from child to adult services and a lack of guidance on how to achieve this effectively. This paper reviews the difficulties of young people with ADHD and their families who are transitioning between services; we review transition from the child and adult health teams' perspectives and identify barriers to the transition process. We conclude with recommendations on how to develop transition services for young people with ADHD.</p
Scotland and Ulster connections in the seventeenth century : Sir Robert Adair of Kinhilt and the Scottish Parliament under the covenanters
No full textIt has long been recognized that a culture of mobility has existed in Scottish society. In the sixteenth and seventeenth centuries the main destinations for Scottish migrants were Poland, Scandinavia, and Ulster, although there were many other destinations too
Evoking the Possibility of Presence:Textual and Ideological Effects of Linguistic Negation in Written Discourse
No full textThis thesis explores the textual and ideological effects of linguistic negation in written texts. It argues that when language users process negation, understanding its use in context is as much about the possibility of presence as it is about the actuality of absence. This gives rise to a variety of effects in texts from contributing to the construction of fictional characters to potentially influencing readers’/hearers’ view of the world they inhabit. This thesis brings together research on the theoretical aspects of how negation works to present a new approach to linguistic negation in written discourse. It also demonstrates how this approach can be applied in the analysis of the conceptual practice of negating. The approach presented is made up of three main elements; negation is presuppositional, is realised through a wide variety of linguistic forms beyond the morphosyntactic core forms (not, no, never, none, un-, in-, and so on) and includes semantic and pragmatically implied forms. These two elements combine to give rise to implied meaning in context. Having outlined this approach to negation, it is then applied in the analysis of literary and non-literary texts to explain the textual and ideological effects that arise from its use
The effect of age on vertex-based measures of the grey-white matter tissue contrast in autism spectrum disorder
No full textBackground: Histological evidence suggests that autism spectrum disorder (ASD) is accompanied by a reduced integrity of the grey-white matter boundary. This has also recently been confirmed by a structural neuroimaging study in vivo reporting significantly reduced grey-white matter tissue contrast (GWC) in adult individuals (18–42 years of age) with ASD relative to typically developing (TD) controls. However, it remains unknown whether the neuroanatomical differences in ASD at the grey-white matter boundary are stable across development or are age-dependent.
Methods: Here, we examined differences in the neurodevelopmental trajectories of GWC in a cross-sectional sample of 77 male ASD individuals and 76 typically developing (TD) controls across childhood and early adulthood (from 7 to 25 years).
Results: Using nested model comparisons, we first established that the developmental trajectory of GWC is complex in many regions across the cortex and includes linear and non-linear effects of age. Second, while ASD individuals have significantly reduced GWC overall, these differences are age-dependent and are most prominent during childhood (< 15 years).
Conclusions: Taken together, our findings suggest that differences in GWC in ASD are unlikely to reflect atypical grey matter cytoarchitecture alone, but may also represent other aspects of the cortical architecture such as age-dependent variability in myelin integrity
Fronto-striatal circuitry and inhibitory control in autism: Findings from diffusion tensor imaging tractography
No full textIntroduction
Repetitive behaviour and inhibitory control deficits are core features of autism; and it has been suggested that they result from differences in the anatomy of striatum; and/or the ‘connectivity’ of subcortical regions to frontal cortex. There are few studies, however, that have measured the micro-structural organisation of white matter tracts connecting striatum and frontal cortex.
Aims
To investigate differences in bulk volume of striatum and micro-structural organisation of fronto-striatal white matter in people with autism; and their association with repetitive behaviour and inhibitory control.
Methods
We compared the bulk volume of striatum (caudate nucleus, putamen and nucleus accumbens) and white matter organisation of fronto-striatal tracts using (respectively) structural magnetic resonance imaging (sMRI) and tract specific diffusion tensor imaging (DTI) measures in 21 adults with autism and 22 controls. We also assessed performance on a cognitive inhibition (go/nogo) task.
Results
Bulk volume of striatal structures did not differ between groups. However, adults with autism had a significantly smaller total brain white matter volume, lower fractional anisotropy of white matter tracts connecting putamen to frontal cortical areas, higher mean diffusivity of white matter tracts connecting accumbens to frontal cortex and worse performance on the go/nogo task. Also, performance on the go/nogo task was significantly related to anatomical variation when both groups were combined; but not within the autism group alone.
Conclusions
These data suggest that autism may be associated with differences in the anatomy of fronto-striatal white matter tracts
Investigating the ‘empire of secrecy’ — three decades of reporting on the secret state
No full textThis thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University LondonIt has often been argued that journalism has been the most effective means of holding the intelligence services to account in western democracies. This thesis examines whether that proposition holds true in the United Kingdom and if so, whether such oversight has been consistent. Accountability by the news media is compared with the expanding range of UK official oversight mechanisms. The author utilises a body or work from over three decades of reporting on the intelligence services and further research on accountability to examine these questions. The author suggests this work is timely, given the controversy prompted by the former National Security Agency contractor, Edward Snowden, who leaked a substantial archive of secret intelligence documents. This thesis concludes that the news media were often effective, if not consistent, in bringing intelligence to account in the second half of the 20th century. Since the start of the 21st century monitoring the secret state has become more challenging as a result of a changing economic, global and national political environment. Government legislation and technology makes it increasingly difficult for journalists to obtain confidential sources and then undertake their Fourth Estate role. Finding new methodologies is an urgent task for journalists, as history reveals that if intelligence agencies operate without scrutiny from outside government, abuses take place. Never before has government and its intelligence services had such powers and techniques of invasive mass surveillance available, and thus the potential to control the population and particularly those who dissent
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