124,687 research outputs found
Emerging biological drugs: A new therapeutic approach for Systemic Lupus Erythematosus. An update upon efficacy and adverse events
No full textB-cells abnormalities leading to autoantibody production play a central role in Systemic Lupus Erythematosus
(SLE) pathogenesis. B-cell targeted therapies, including anti-B lymphocyte stimulator (BLyS) and anti-CD20
monoclonal antibodies, are at forefront of new SLE treatments. Biologic agents targeting specific pathways
(i.e. T-B lymphocyte interaction, cytokines and complement) have been also proposed as new tools for SLE
treatment. In this review we will focus on biological drugs whose potential efficacy has been evaluated in
open-label and randomized clinical trials
High-energy resummation in heavy-quark pair photoproduction
No full textWe present our predictions for the inclusive production of two heavy quark–antiquark pairs, separated by a large rapidity interval, in the collision of (quasi-)real photons at the energies of LEP2 and of some future electron–positron colliders. We include in our calculation the full resummation of leading logarithms in the center-of-mass energy and a partial resummation of the next-to-leading logarithms, within the Balitsky–Fadin–Kuraev–Lipatov (BFKL) approach
Mueller-Navelet jets at the LHC: Discriminating BFKL from DGLAP by asymmetric cuts
No full textThe Mueller-Navelet di-jet production process represents an ultimate test field of pQCD in the high-energy limit. Several experimental analyses carried out so far are in a good agreement with theoretical predictions, based on collinear factorization and BFKL resummation of energy logarithms in the next-to-leading approximation, with the CMS experimental data at center-of-mass energy equal to 7 TeV. However, the question if the same data can be described also by fixed-order perturbative approaches has not yet been fully answered. We discuss how the use of partially asymmetric cuts in the transverse momenta of the detected jets allows to discriminate between BFKL-resummed and fixed-order predictions (the latter in the high-energy limit) in observables related with this process at the LHC
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
High energy resummation in dihadron production at the LHC
No full textWe propose to study at the Large Hadron Collider (LHC) the inclusive production of a pair of hadrons (a "dihadron" system) in a kinematics where two detected hadrons with high transverse momenta are separated by a large interval of rapidity. This process has much in common with the widely discussed Mueller-Navelet jet production and can also be used to access the dynamics of hard proton-parton interactions in the Regge limit. For both processes large contributions enhanced by logarithms of energy can be resummed in perturbation theory within the Balitsky-Fadin-Kuraev-Lipatov (BFKL) formalism with next-to-leading logarithmic accuracy. The experimental study of dihadron production would provide an additional clear channel to test the BFKL dynamics. We present here the first theoretical predictions for cross sections and azimuthal angle correlations of the dihadrons produced with LHC kinematics
Mueller-Navelet jets at LHC: BFKL versus high-energy DGLAP
No full textThe production of forward jets separated by a large rapidity gap at LHC, the so-called Mueller-Navelet jets, is a fundamental testfield for perturbative QCD in the high-energy limit. Several analyses have already provided us with evidence about the compatibility of theoretical predictions, based on collinear factorization and BFKL resummation of energy logarithms in the next-to-leading approximation, with the CMS experimental data at 7 TeV of centerof- mass energy. However, the question if the same data can be described also by fixed-order perturbative approaches has not yet been fully answered. In this paper we provide numerical evidence that the mere use of partially asymmetric cuts in the transverse momenta of the detected jets allows for a clear separation between BFKL-resummed and fixed-order predictions in some observables related with the Mueller- Navelet jet production process
Mueller-Navelet jets at LHC: Discriminating BFKL from DGLAP by asymmetric cuts
No full textThe Mueller-Navelet di-jet production process represents an ultimate testfield of pQCD in the high-energy limit. Several experimental analyses carried out so far are in good agreement with theoretical predictions, based on collinear factorization and BFKL resummation of energy logarithms in the next-to-leading approximation, with the CMS experimental data at center-of-mass energy equal to 7 TeV. However, the question if the same data can be described also by fixed-order perturbative approaches has not yet been fully answered. We discuss how the use of partially asymmetric cuts in the transverse momenta of the detected jets allows to discriminate between BFKL-resummed and fixed-order predictions (the latter in the high-energy limit) in observables related with this process at LHC
Mueller–Navelet jets at 13 TeV LHC: dependence on dynamic constraints in the central rapidity region
No full textWe study the production of Mueller–Navelet jets at 13 TeV LHC, within collinear factorization and including the BFKL resummation of energy logarithms in the next-to-leading approximation. We calculate several azimuthal correlations for different values of the rapidity separation Y between the two jets and evaluate the effect of excluding those events where, for a given Y, one of the two jets is produced in the central region
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