1,720,996 research outputs found

    Treatment of symptom-free Helicobacter pylori-positive subjects

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    Aim: To investigate the need for treatment in symptom-free Helicobacter pylori-positive subjects. Design: Large-scale ongoing study of seropositive blood donors allocated to six treatment regimens. Methods: Specific immunoglobulin G antibodies to H. pylori were measured by enzyme-linked immunosorbent assay of serum from 1010 Bologna blood donors over 1 year. Out of 442 positive subjects, 298 were endoscoped with infection confirmed in 279. Six treatment regimens were applied, (1) placebo; (2) 240 mg colloidal bismuth subcitrate twice a day plus 500 mg tinidazole three times a day for 2 weeks; (3) 300 mg ranitidine each day for 4 weeks; (4) 120 mg colloidal bismuth subcitrate four times a day plus 500 mg amoxycillin four times a day for 7 days plus 500 mg tinidazole four times a day on days 5-7; (5) standard triple therapy for 2 weeks with amoxycillin; or (6) standard triple therapy for 2 weeks with tetracyclin. Endoscopy was repeated 4 weeks after the end of the treatment. Results: So far, repeat endoscopy has been performed in 162 subjects after the treatment was completed. Of these, 103 had been diagnosed as having active gastritis (determined histologically) and 59 a peptic ulcer (42 duodenal, 17 gastric). The H. pylori eradication rate by treatment group was 0% for group 1, 31% for group 2, 0% for group 3, 59% for group 4, 85% for group 5 and 94% for group 6. Continuation of study: The follow-up of these subjects will provide information on the need for treatment in symptom-free subjects

    Comparison of urease tests for the diagnosis of Helicobacter pylori infection

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    Aim: To assess the value of different types of urease tests in diagnosing Helicobacter pylori infection. Method: Survey of recent studies. Results: Urease tests can now diagnose H. pylori infection within a few minutes with high sensitivity and specificity, although some positive cases may be missed. Other tests are still required to provide histological information and to determine the sensitivity or resistance of the bacterium to antimicrobial drugs. Conclusions: New urease tests are rapid and highly accurate but must be complemented by slower, more expensive histological and bacterial culture tests

    Monitoraggio e conservazione della flora e della vegetazione costiera nell’Area Marina Protetta di Capo Carbonara (Sardegna Sud Orientale)

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    A review of the status of Taxus baccata L. forests in Sardegna (Italy) is given. 6 new sites have been discovered (to add to the 41 formerly known sites). The species have a large range of altitudes -50-1550 m-, but it uses to live from the upper Meso-Mediterranean (MM) to the medium Supra-Mediterranean (SM) thermotype, preferablely under humide (H) or upper-subhumide (SH) ombrotype. As a result of this work two plant associations have been proposed: 1) Phillyreo latifoliae-Taxetum baccatae nom. prov., for acid substrata, having its best sites by 500-900 m, thermotype MM, ombrotype upper-SH to lower-H, and being enclosed in Fraxino orni-Quercion ilicis (Quercetalia ilicis, Quercetea ilicis); and 2) Glechomo sardoae-Taxetum baccatae nom. prov., on basic substrata, 900-1500 m, optimum SM lower-H, syntaxonomically included in Pino calabricae-Quercion congestae (Quercetalia pubescente-petraeae, Querco roboris-Fagetea sylvaticae). In addition 2 sub-associations have been described for the Glechomo-Taxetum baccatae: ilicetosum aquifolii nom. prov. and rhamnetosum alpinae nom. prov

    Treatment of symptom-free Helicobacter pylori-positive subjects

    No full text
    Aim: To investigate the need for treatment in symptom-free Helicobacter pylori-positive subjects. Design: Large-scale ongoing study of seropositive blood donors allocated to six treatment regimens. Methods: Specific immunoglobulin G antibodies to H. pylori were measured by enzyme-linked immunosorbent assay of serum from 1010 Bologna blood donors over 1 year. Out of 442 positive subjects, 298 were endoscoped with infection confirmed in 279. Six treatment regimens were applied, (1) placebo; (2) 240 mg colloidal bismuth subcitrate twice a day plus 500 mg tinidazole three times a day for 2 weeks; (3) 300 mg ranitidine each day for 4 weeks; (4) 120 mg colloidal bismuth subcitrate four times a day plus 500 mg amoxycillin four times a day for 7 days plus 500 mg tinidazole four times a day on days 5-7; (5) standard triple therapy for 2 weeks with amoxycillin; or (6) standard triple therapy for 2 weeks with tetracyclin. Endoscopy was repeated 4 weeks after the end of the treatment. Results: So far, repeat endoscopy has been performed in 162 subjects after the treatment was completed. Of these, 103 had been diagnosed as having active gastritis (determined histologically) and 59 a peptic ulcer (42 duodenal, 17 gastric). The H. pylori eradication rate by treatment group was 0% for group 1, 31% for group 2, 0% for group 3, 59% for group 4, 85% for group 5 and 94% for group 6. Continuation of study: The follow-up of these subjects will provide information on the need for treatment in symptom-free subjects

    Comparison of urease tests for the diagnosis of Helicobacter pylori infection

    No full text
    Aim: To assess the value of different types of urease tests in diagnosing Helicobacter pylori infection. Method: Survey of recent studies. Results: Urease tests can now diagnose H. pylori infection within a few minutes with high sensitivity and specificity, although some positive cases may be missed. Other tests are still required to provide histological information and to determine the sensitivity or resistance of the bacterium to antimicrobial drugs. Conclusions: New urease tests are rapid and highly accurate but must be complemented by slower, more expensive histological and bacterial culture tests

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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