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    Proceedings of the first Combivet and Baltic Society of Extracellular Vesicles joint conference 2022 : 30th September & 1st of October, 2022

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    About COMBIVET & BALTIC SOCIETY OF EXTRACELLULAR VESCILES JOINT CONFERENCE 2022. The Combivet and Baltic Society of Extracellular Vesicles (BSEV) Joint Conference is organized by the COMBIVET ERA Chair of Comparative Medicine in the Institute of Veterinary Medicine and Animal Sciences of the Estonian University of Life Sciences and Baltic Society of Extracellular Vesicles. The program is supported by the European Union (Horizon 2020 research and innovation programme under grant agreement No 857418).Welcome. I am extremely happy to welcome you to the first COMBIVET and BSEV joint conference 2022, organized by COMBIVET ERA Chair of Comparative Medicine in the Institute of Veterinary Medicine and Animal Sciences of the Estonian University of Life Sciences and Baltic Society of Extracellular Vesicles. I am also proud to say that this would be the 6th conference on Extracellular Vesciles (EVs) organized by the Fazeli Lab. Due to pandemic and its consequences, we hosted our last conference as a hybrid event, therefore on behalf of the organizing committe, I am delighted to welcome you all to a full physical meeting this year. In recent years, EVs have gained a considerable interest across different scientific communities, particularly those working with cancer, infectious and inflammatory diseases. In addition, EVs have emerged as important mediators of cell-cell interactions, making them very attractive targets for theranostics. In the past EVs were a hot topic in just Human Medicine, now investigators in Veterinary Medicine and even those working with plants and microorganisms are becoming interested in working on this amazing new and attractive field of science. Under the COMBIVET ERA Chair of Comparative Medicine in the Institute of Veterinary Medicine and Animal Sciences of the Estonian University of Life Sciences and previously, under the ERA chair of Translational Genomics program of the University of Tartu, we have formed a nucleus of collaboration between different researchers interested in studying EVs, characteristizing, and their possible role in a range of human and animal diseases and conditions including infertility and other reproductive disorders, osteoarthritis, and psoriasis. Subsequently, we have gained substantial experience in different aspects of the purification and characterization of EVs. Most importantly, we have managed to publish our EV research studies in many reputed journals, created excellent collaborations and apply our knowledge about EVs to many new fields of life science and medicine. Recently with extablishment of Baltic Society of Extracellular Vesicles (BSEV), we started collaborating more with scientist and professionals working in in the Baltic region. Therefore, we believe that by organizing this conference, we could create a platform for sharing and intergrating multidischiplinary scientific knowledge, hence creating more opportunities for networking for collaboration and career development. I would like to thank all the speakers, participants and organizing committee of the conference for your share of contribution to the success of the conference. I sincerely hope that the conference will provide a solid platform for all to engage in meaningful scientific debates and discussions. It is my sincere wish that Combivet and BSEV joint conference 2022 will be a resounding success. Alireza Fazeli, Professor, ERA Chair of Comparative Medicine, Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Tartu, EstoniaThe program is supported by the European Union (Horizon 2020 research and innovation programme under grant agreement No 857418)

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Combivet and BSEV Joint Summer School

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    About COMBIVET AND BSEV JOINT SUMMER SCHOOL 2022. The Combivet and BSEV Joint Summer School is organized by the COMBIVET ERA Chair of Comparative Medicine in the Institute of Veterinary Medicine and Animal Sciences of the Estonian University of Life Sciences and Baltic society of Extracellular Vesicles. The program is supported by the European Union (Horizon 2020 research and innovation programme under grant agreement No 857418). In this exclusive summer school, the students will get hands on experience in the basics of EV isolation, characterization and the related data analysis from a panel of international experts with years of experience in handling EVs. A series of lectures covering the required theoretical knowledge, best practices, tips and tricks, troubleshooting and adherence to the standards set by the International Society for Extracellular vesicles (ISEV) would also be offered. Latest developments in the field such as mass production of EVs will be thoroughly discussed along with the basics such as size exclusion chromatography, tangential flow filtration, ultracentrifugation, nanoparticle tracking analysis, flow cytometry for EVs, EV RNA extraction and characterization. The school is well suited for EV researchers who require a firm foundation in basics to begin their journey into the world of EV research.It's a pleasure to welcome you to the first hands-on training school of "Basics to work with Extracellular Vesicles" jointly organized by the COMBIVET ERA Chair of Comparative Medicine in the Institute of Veterinary Medicine and Animal Sciences of the Estonian University of Life Sciences, Faculty of Biomedicine and Biotechnology, University of Tartu and Baltic Society of Extracellular Vesicles. However, this is also the 5th research school organized by the Fazeli lab on "Basics to work with Extracellular Vesicles". In recent years, Extracellular Vesicles (EVs) have gained considerable interest across different scientific communities, particularly those working with cancer, infectious and inflammatory diseases. In addition, EVs have emerged as important mediators of cell-cell interactions, making them very attractive targets for biomarker discovery platforms and therapeutics. If in the past EVs were a hot topic in just Human Medicine, now investigators in Veterinary Medicine and even those working with plants and microorganisms are becoming interested in working on this amazing new and attractive field of science. Under the COMBIVET ERA Chair of Comparative Medicine in the Institute of Veterinary Medicine and Animal Sciences of the Estonian University of Life Sciences and previously, under the ERA chair of Translational Genomics program of the University of Tartu, we have formed a nucleus of collaboration between different researchers interested in studying EVs, their characteristics, and their possible role in a range of human and animal diseases and conditions including infertility and other reproductive disorders, osteoarthritis, and psoriasis. Subsequently, we have gained substantial experience in different aspects of the purification and characterization of EVs. Most importantly, we have managed to publish our EV research studies in many reputed journals, bult up excellent collaborations and apply our knowledge about Evs to many new fields of science and medicine. Recently, with the establishment of Baltic Society of Extracellular vesicles, we started collaborating more with scientist and professionals working in the field of EVs in the Baltic region. The current research school is aimed at introducing the trainees to the basics of working with EVs. Given their minute size and enigmatic nature, studying EVs' physical and chemical characteristics requires a specific set of skills, many of which may be unfamiliar even to veteran biomedical researchers. Hence, with this training school, our mission is to impart these skills and educate trainees with skills helping them shape the future generation of researchers working on this exciting new field of science. This training school would not have been possible without the hard work of the members of the Fazeli lab in Tartu, who were instrumental in organizing the event, and our collaborators from around the world and the researchers who have dedicated their valuable time to share their expert knowledge with us during the course of the research school. I would like to thank all of them and you for participating in the EV Summer School. Alireza Fazeli, Professor ERA Chair of Comparative Medicine in the Institute of Veterinary, Medicine and Animal Sciences, Estonian University of Life Sciences, Tartu, EstoniaHorizon 2020 research and innovation programme under grant agreement No 85741

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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