1,722,061 research outputs found
Circular intensity differential scattering of light for biophotonics applications
No full textThis thesis demonstrate the application of a label-free, non-invasive biophysical method based on angle-resolved light scattering calculations to characterize different biological samples; virus particles, chromatin fiber, and hierarchical chiral polymers.
Chapter 1 provides an introduction on the foundation of electromagnetic theory, light scattering phenomenon, Mueller scattering matrix and its applications to characterize various samples based on numerical simulations and experimental measurements. A numerical method to calculate light scattering quantities, discrete dipole approximation (DDA) method is discussed. In this thesis we have performed the electromagnetic scattering calculations using the DDA method implemented as ADDA code.
Chapter 2 demonstrates the angle-resolved circularly polarized light scattering calculations to characterize virus model particles. A coronavirus particle is modeled as having a spherical shaped envelope with cylindrical spikes projected from the envelope surface, and the single-stranded RNA genome polymer has been mimicked with a toroidal helix. The influence of genome polymer packaged as a standard helix in the virion core is also demonstrated. We investigated four different electromagnetic models: (i) a nucleated sphere with spikes that is a coronavirus particle, (ii) a nucleated sphere with no spikes, (iii) a homogeneous sphere, and (iv) a respiratory fluid containing a virus particle. The angular pattern of scattered circularly polarized light, the circular intensity differential scattering of light (CIDS), served as a particle's signature. This scattering signature is found sensitive to the chiral parameters that reveal information about the particles. The effect of changes in the RNA polymer, changes in its packaging, number of turns, handedness, and size are demonstrated on the scattering calculations. Additionally, the extinction efficiency, the depolarization ratio, the total scattered intensity, and the effect of changes in the wavelength of incident light on these scattering quantities are investigated. This biophysical method can offer a label-free identification of virus particles and can help understand their interaction with light.
Chapter 3 focus on the the characterization of chromatin organization. Understanding the structural organization of chromatin is essential to comprehend the gene functions. The chromatin
organization changes in the cell cycle, and it conforms to various compaction levels. We investigated a chromatin solenoid model with nucleosomes shaped as cylindrical units arranged in a helical array. The solenoid with spherical-shaped nucleosomes was also modeled. The changes in chiral structural parameters of solenoid induced different compaction levels of chromatin fiber. We calculated the angle-resolved scattering of circularly polarized light to probe the changes in the organization of chromatin fiber in response to the changes in its chiral parameters. The electromagnetic scattering calculations were performed using discrete dipole approximation (DDA). In the chromatin structure,
nucleosomes have internal interactions that affect chromatin compaction. The merit of performing computations with DDA is that it takes into account the internal interactions. We demonstrated sensitivity of the scattering signal's angular behavior to the changes in these chiral parameters: pitch, radius, the handedness of solenoid, number of solenoid turns, the orientation of solenoid, the orientation of nucleosomes, number of nucleosomes, and shape of nucleosomes. These scattering calculations can potentially benefit applying a label-free polarized-light-based approach to characterize chromatin DNA and chiral polymers at the nanoscale level.
Chapter 4 demonstrates the differential scattering of circularly polarized light to characterize the macromolecular structures consisting of hierarchical chirality. We modeled the B-DNA structure composed of a double-helix and a base-pairs helical structure. The angle-resolved scattering of circularly polarized light calculated for the B-DNA shows the additive behavior of the scattering signal contributed from the two individual chirality levels of B-DNA structure, a double-helix and a base-pairs helix. This additive behavior of angle-resolved scattering signal has also been demonstrated for other macromolecular structures comprising different chirality levels; a biological cell is also mimicked as a nucleated sphere, a sphere with a helical nucleus in its core. The individual chiral features of a structure add up to the angle-resolved scattering signal of circularly polarized light produced by the parent structure. These electromagnetic wave scattering calculations can offer a label-free approach to characterize chiral macromolecular structures with hierarchical chirality
Muhammad Waseem - Evaluation of Radio over Plastic Optical Fiber Communications
No full textEvaluation of Radio over Plastic Optical Fiber Communication
sj-docx-2-smo-10.1177_20503121231157217 – Supplemental material for Prevalence of low back pain among medical doctors of the teaching hospitals in Karachi, Pakistan: A cross-sectional survey
No full textSupplemental material, sj-docx-2-smo-10.1177_20503121231157217 for Prevalence of low back pain among medical doctors of the teaching hospitals in Karachi, Pakistan: A cross-sectional survey by Salman Javed, Muhammad Hamza Dawood, Muhammad Waseem Memon, Ibrahim Zahid Selod and Arshi Seja in SAGE Open Medicine</p
sj-docx-1-smo-10.1177_20503121231157217 – Supplemental material for Prevalence of low back pain among medical doctors of the teaching hospitals in Karachi, Pakistan: A cross-sectional survey
No full textSupplemental material, sj-docx-1-smo-10.1177_20503121231157217 for Prevalence of low back pain among medical doctors of the teaching hospitals in Karachi, Pakistan: A cross-sectional survey by Salman Javed, Muhammad Hamza Dawood, Muhammad Waseem Memon, Ibrahim Zahid Selod and Arshi Seja in SAGE Open Medicine</p
sj-docx-3-smo-10.1177_20503121231157217 – Supplemental material for Prevalence of low back pain among medical doctors of the teaching hospitals in Karachi, Pakistan: A cross-sectional survey
No full textSupplemental material, sj-docx-3-smo-10.1177_20503121231157217 for Prevalence of low back pain among medical doctors of the teaching hospitals in Karachi, Pakistan: A cross-sectional survey by Salman Javed, Muhammad Hamza Dawood, Muhammad Waseem Memon, Ibrahim Zahid Selod and Arshi Seja in SAGE Open Medicine</p
ڈا کٹر محمد وسیم انجم کی دیباچہ نگاری
No full textThis abstract is a glance at the Debacha Nigari of Dr. Muhammad Waseem Anjum. Dr Muhammad Waseem is prominent researcher, literary man and critic in Urdu literature. He was born in Kahuta in 1961. He wrote many books especially on the subject of research and iqbaliat. He is not a poet but he well knows the literary techniques of the poetry. He is a distinct Debacha Nigar due to his philosophical attitude and deepness of the subject. His writings are based on curiosity and in his literary style there is decency and novelty. Dr. Muhammad Waseem started his work with “Harf-e-Chand” and therein he highlighted the deteriorated situation of the Muslims and identified the reasons of their various troubles and downfall. In short Dr. Muhammad Waseem literary work on Debach Negair apprise us about many books, writers and poets
MISUSE OF ANTIBIOTICS IN MANAGEMENT OF DIARRHEA AND COUGH AT PRIMARY HEALTHCARE CENTERS
No full textDr. Muhammad Waseem Iqbal*, Dr. Badar Iqbal and Dr. Niaz Ahma
Antecedents and outcomes of employee-based brand equity Advances in business strategy and competitive advantage./ Muhammad Waseem Bari, Muhammad Abrar, Emilia Alaverdov.
No full textIncludes bibliographical references and index."The purpose of this book is to enhance researchers and practitioners' understanding of how brand equity (employee perspective) could be fruitful in understanding and learning different theories and concepts with the interaction of different industries and cultures"--Chapter 1. Employee-based brand equity and factors of employee-brand association -- Chapter 2. Impact of employee-based brand equity on customer-based brand equity -- Chapter 3. Psychological capital as an antecedent of employee engagement and its relationship with intention to stay -- Chapter 4. Employee-based brand equity and competitive advantage -- Chapter 5. Employee-based brand equity: a literature review and a way forward -- Chapter 6. Knowledge-hiding behaviors and employee-based brand equity -- Chapter 7. Impact of leader-member exchange on innovative work behavior: role of employee-based brand equity, humor, and humble leadership -- Chapter 8. An exploration of the factors affecting brand association -- Chapter 9. Knowledge-sharing culture and employee-based brand equity -- Chapter 10. Workplace discrimination during international work assignments -- Chapter 11. Middle East: who will dominate in the region a case of China -- Chapter 12. Reviewing the employee branding process to gain firm competitive advantage -- Chapter 13. Linking psychological contract with employee-based brand equity -- Chapter 14. The impact of brand experience, service quality, and perceived value on word of mouth and repurchase intentions -- Chapter 15. A conceptual action plan for reducing environmental pollution through sustainable clothing purchase intention and behavior: a systematic review.1 online resource (xix, 297 pages)
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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