1,722,199 research outputs found

    Application of genus Cassia in the treatment of Constipation: A systematic review

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    Meta-analysis of genus Cassi

    Leishmaniasis: A Serious Public Health Concern in Pakistan

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    1*Mustafa, M.S., 1Imran M., 1Sindhu, Z.D., 1Khan M.K., 1Malik, M.A., 1Naseer, M.U. and 2Qudoos, A. *Corresponding presenter: Muhammad Shahzad Mustafa 1*Research Focus: Protozoology 1*Student Level: M.Phil. Scholar 1 [email protected] Department of Parasitology, University of Agriculture Faisalabad, Pakistan 2 Central Hi-Tech Laboratory, University of Agriculture Faisalabad, Pakista

    Author Correction: Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials.

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    The original version of this Article contained an error in the spelling of the author Muhammad Shahzad, which was incorrectly given as Muhammad Shehzad. This has now been corrected in both the PDF and HTML versions of the Article

    PROTACs: The Future of Leukemia Therapeutics

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    The fight to find effective, long-lasting treatments for cancer has led many researchers to consider protein degrading entities. Recent developments in PROteolysis TArgeting Chimeras (PROTACs) have signified their potential as possible cancer therapies. PROTACs are small molecule, protein degraders that function by hijacking the built-in Ubiquitin-Proteasome pathway. This review mainly focuses on the general design and functioning of PROTACs as well as current advancements in the development of PROTACs as anticancer therapies. Particular emphasis is given to PROTACs designed against various types of Leukemia/Blood malignancies

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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