5 research outputs found
Rapid investigation expiry drug green corrosion inhibitor on mild steel in NaCl medium
No full textThe unused expired clinical drugs are a major environmental hazardous pollutant due to the pharmaceutically active organic compounds present in it. Until recently, a quantum of unused drugs is being disposed through sewers, drainage, sediment are a threat to the public health. Several researchers have already reported the potential use of expired drugs as corrosion inhibitors in both acidic and alkaline medium. In this paper, we have reported three different drug molecules which have crossed the expiry date but not beyond six months. The drugs considered are rabeprazolesodium, domperidone and benfotiamine. Mild steel (MS) specimens were immersed 5 days with and without drug molecule in 3.5 wt% medium film formed on MS surface. These films were then analysed for crystallinity, surface morphology, iron complex, DFT and functional groups by XRD, SEM, and 3D profilometer, FTIR, UV and EPR. The experimental and theoretical results are good agreement with each other.No Full Tex
Chronicling the Self: A Feminist Approach to Mrinal Pande's Daughter's Daughter
No full textAutobiography writing is a means for women writers to explore their inner-most recesses of their selves. Mrinal Pande's Daughter's Daughter is a rare type of the portrayal of self-wherein the author creates a fictional self to describe her survival story of being a daughter's daughter. In the autobiography the author maintains a distance with her own self, speaking through a girl of the age span f two to ten. In the story of her 'self', Mrinal Pande, introspects, observes, comments and narrates her past through her mouthpiece, Tinu. The present paper focuses in detail the pain of being a girl child in a patriarchal society and the author's decision not to be a victim of patriarchal domination. 
ASSESSMENT OF LEFT ATRIAL FUNCTION IN PATIENTS WITHMITRAL VALVE DISEASES
No full textABSTRACTObjective:To observe and assess left atrial (LA) function by observing the differences in conventional Doppler echo parameters of left ventricular inflow, Left atrial appendage, among patients with mitral valve disease.Methods: Forty three mitral valve disease subjects appearing consecutively for echocardiogram (ECHO) test at the cardiology department in a tertiary care hospital were recruited into the study as per the pre-set inclusion and exclusion criteria. The data from the ECHO was pooled using Microsoft excel and analyzed using SPSS software by application of appropriate statistical tests.Results:Of the 43 objects, 39 had MS, 3 had MR and 2 of them were found to have both MS and MR. The major presenting symptom as observed in 33 subjects, was dyspnea. LA maximum volume was found to be 91±59 ml and minimum was 66±51 ml. Left atrial expansion index was 128±91. Left atrial active emptying fraction was 29±13 and passive emptying fraction was 31±15. No significant change in LA global strain among groups with MR and without MR was observed. Further, no significant difference was observed in left atrial indices like left atrial emptying fraction, left atrial passive emptying fraction, atrial fraction, Left atrial expansion index among  groups having MR and no MR.Conclusion:LA contractile, reservoir and conduit function was significantly reduced in mitral valve diseases due to increased hemodynamic load. No significant difference was noted in global LA strain irrespective of MS or MR.Key Words: Valvular disease; Left atria; Strain; Contractile functio
Assessing the sustainability of threadfin bream fishery along South-eastern coast of the Arabian Sea: A comprehensive analysis of climate change impact and fishing frontiers
No full textThe study aimed to assess the cumulative impact of climate change and sustainable fishing levels on the long-term sustainability of threadfin breams, a demersal species inhabiting along south-eastern coast of the Arabian Sea (SEAS). We utilized the dataset derived from the commercial fisheries in the SEAS region and addressed the influence of dynamics in fishing and environmental factors. The threadfin breams stock status was estimated by analyzing the fluctuations in Catch Per Unit Effort and by employing methods, viz. the Monte Carlo Catch- Maximum Sustainable Yield and Bayesian Schaefer Model. The investigation found that the catch rate of threadfin breams declined as fishing intensity increased in terms of effectiveness of advanced fishing methods. This empirical inquiry leveraged the Generalized Additive Model to assess the impact of environmental parameters on the fish stock. The analysis unveils a notable positive influence on this fish group, signifying a substantial response to increased precipitation. In contrast, deviations in Sea Surface Temperature, Sea Surface Salinity, ocean isothermal layer depth, and surface currents revealed adverse effects surpassing the optimal threshold. The targeted stock of threadfin breams exhibits a medium level of resilience, as indicated by the existing data, the investigation concludes that optimizing fishing practices could aid in replenishing the stock, fostering future sustainability. This conclusion holds true even in the face of potential negative influences from environmental parameters to a certain extent. Overall, the study provides important insights into the impact of climate change and sustainable fishing practices on the sustainability of a demersal resource in the SEAS and emphasizes the innovative ways to manage fishery resources in a manner that is ecologically sustainable and yet economically viable and socially acceptable
Health-related quality of life at 30 days among Indian patients with acute myocardial infarction results from the ACS QUIK trial
No full textBackground:
Despite a high cardiovascular disease burden, data on patient-reported health status outcomes among individuals with cardiovascular disease in India are limited.
Methods and Results:
Between November 2014 and November 2016, we collected health-related quality of life data among 1261 participants in the ACS QUIK trial (Acute Coronary Syndrome Quality Improvement in Kerala). We used a translated, validated version of the Seattle Angina Questionnaire administered 30 days after discharge for acute myocardial infarction, wherein higher scores represent better health status. We compared results across sex, myocardial infarction type, and randomization status using regression models that account for clustering and temporal trends. Mean (SD) age was 60.8 (13.7) years, 62% were men, and 63% presented with ST-segment–elevation myocardial infarction. More than 2 out of 5 respondents (44%) experienced angina 30 days after hospitalization, but most (68% of respondents with angina; 27% of the total sample) experienced it less than once per week (Seattle Angina Questionnaire angina frequency score 60). Respondents rated high median (interquartile range [IQR]) scores for angina frequency (100.0 [80.0–100.0]) overall with similar unadjusted scores by sex, but between-hospitality variability was high. Median (IQR) physical limitation scale response was 58.3 (41.7–77.8), which is consistent with limitations in moderate- and high-intensity activities at 30-day follow-up. Older respondents had more angina frequency and physical limitations and lower treatment satisfaction and quality of life. Women had greater physical limitations (median [IQR], 52.8 [38.9–72.2] for women versus median [IQR], 61.1 [44.4–80.6] for men; P<0.01). Overall treatment satisfaction was high with median (IQR) score, 81.3 (75.0–93.8), but overall quality of life was lower with median (IQR) score, 66.7 (50.0–83.3). Allocation to the quality improvement intervention group had the strongest direct association with higher quality of life (difference, 4.2; P=0.03), but overall effects were modest.
Conclusions:
This study represents the largest report of quality of life among myocardial infarction survivors in India with variability across age, sex, and quality improvement intervention status. Wide variability demonstrated across hospitals warrants further study.
Clinical Trial Registration:
URL: https://www.clinicaltrials.gov. Unique identifier: NCT02256657
