17 research outputs found
이상의 「종생기」에 나타난 사랑, 죽음, 예술
No full textThis essay aims at overcoming the two main interpretations of Yi Sangs ecriture. One is the biographical interpretation which reduces Yi Sangs literature into the documents of his despair and fear and the other is the semiological interpretation which makes his texts a hollow art isolated from life or an abstract play of signs. However, inscription of proper name(Yi Sang) in his texts is not any reference to the author"s presumed identity but a kind of strategy for disrupting Is unified identity and dissolving epistemological representationalism and literary realism. Yi Sangs texts play variations on the theme of nonidentical identity by motives of the mirror, the mask, the double and broken bodies, all of which also disturb the layers of narration. The criticism of representationalism leads to the cognitive way of sign-decoding and the layer of narrative of Yi Sangs texts can, thus, be summarized in some struggles for decoding the violent signs(Oedipus family, modernity and fascism, love, death) which are emitted from the obscure world. Especially, Writing on Death is a peak of Yi Sang"s literature because it envelops love and death in art. His viewpoint of art, condensed into the allusion of Soneynhaeng(少年行), implicates a paradox that one can"t reach art not by wasting his/her life and, in turn, the essence of life which he/she can glimpse only in art, is already dissipated in life itself. Moreover, Yi Sang has made persistent efforts to affirm both life and death by striking pose for suicide and accomplishes amor fati through art(Writing on Death) which overcomes Death and comes repeatedly across life, the world, and the Real
Incredible parenting with Incredible Years?: A Foucauldian analysis of New Zealand Government Perspectives on Parenting and their Implications for Parents and educators in Early Childhood Education
Get PDFThis paper takes a post-structural approach, examining what and how issues are framed in the parenting policy, Incredible Years, through Foucault’s (1977, 1980, 1991, 2003, 2004) notion of governmentality and discursive normalisation . By unpacking discourses of parenting produced by Incredible Years as an accepted parenting programme, it aims to reveal the norm of parenting that is promoted by the current system, and explores how this concept of truth in parenting influences the everyday life of families. The critical analysis of Incredible Years shows that the programme (re)produces the economic/neoliberal discourses as the normal/desirable norm of parenting, thus maintaining/reinforcing the existing power relations in society. The author argues that this notion of a curriculum for parents provides only a limited understanding of the issue, and intensifies inequality and injustice in the milieu. This paper aims to provide the insights for reconceptualising our understanding of parenting for future policy decisions and effective pedagogy
Insulinemic and antioxidant status in normoglycemic subjects with parental history of type 2 diabetes mellitus
No full textAbstract: Diabetes mellitus is affecting human health all over the world. Both environmental and genetic factors are implicated in its pathogenesis. However, the primary of the factors are still debated. Biochemical mechanism(s) in pancreatic b-cell destructions rendering reduced insulin secretion is postulated to be associated with genetic variation and hence the present proposal was aimed to explore insulin secretory capacity (HOMA-%B), insulin sensitivity (HOMA-%S) and total antioxidant status (TAS) in subjects having parental history of type 2 diabetes mellitus (T2DM) and compared with their negative counterpart.
In this cross-sectional study, 96 normoglycemic subjects were enrolled, among them 48 subjects (case) had parental history of T2DM, rest 48 without parental history of T2DM (controls). Blood glucose was measured by glucose oxidase method. Serum total cholesterol, triglycerides and high density lipoprotein (HDL) cholesterol were measured using Dimension®RxL max clinical chemistry system, and serum low density lipoprotein cholesterol (LDL) were calculated by Friedewald formula. Serum insulin was measured by enzyme linked immunosorbent assay. HOMA-%B, HOMA-%S and insulin resistance (HOMA IR) were assessed from fasting glucose and insulin using HOMA2 calculator. Total antioxidant status (TAS) was determined by spectrophotometric technique. Data were expressed as median (range) and Mann Whitney U test was performed to calculate statistical difference between groups using GraphPad Prism (6.02). P value < 0.05 was taken as level of significance.
Median (range) of age (years) was 35.0 (30–50) and 36.5 (30–49) in case and controls respectively. Median (range) of fasting and 2hrs plasma glucose (mmol/L) was 4.9 (3.4–7.7) and 5.9 (4.4–10.6) in case and 4.9 (3.5–5.9) and 5.8 (3.8–7.8) in control respectively. Median (range) of fasting serum insulin (μIU/mL) was 16.1 (4.8–53.2) and 13.3 (2.5–46.3) in case and controls which showed statistical difference (p = 0.0134). HOMA-%B was significantly higher in case compared to control [179 (55–381) vs 98 (56–335), p = 0.001]. HOMA %S was significantly lower [49.3 (17.2–95.8) vs 60.2 (15.5–152.9), p = 0.0365] and HOMA IR was significantly higher [2.0 (1.0–5.8) vs 1.7 (0.7– 6.5), p = 0.0365] in case compared to control subjects with BMI ≤ 25 Kg/m². No significance difference was observed in TAS between case and control group [1296 (579 – 2164) vs 1549 (737 – 2690) μmol/L, p = 0.1330].
Data concluded that normoglycemic offspring of T2DM subjects had higher insulin secretory capacity as evidenced by absolute circulating insulin level and HOMA-%B as a measure of pancreatic b-cell secretion suggesting possible influence on heightened expression of related genes. The plausible mechanism(s) are yet to be identified. Similar levels of total antioxidant status (TAS) in the two groups preclude the oxidative stress involved in the process.
Keywords: Antioxidant status, diabetes, insulinaemic, normoglycemic offspring.
Title: Insulinemic and antioxidant status in normoglycemic subjects with parental history of type 2 diabetes mellitus
Author: Md. Ehsanul Islam khan, Biplob Chandra Shil
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
Vol. 10, Issue 1, April 2022 - September 2022
Page No: 15-20
Publisher: Research Publish Journals
Website: www.researchpublish.com
Published date: 21-April-2022
DOI: https://doi.org/10.5281/zenodo.6475539
Download link (Source): https://www.researchpublish.com/papers/insulinemic-and-antioxidant-status-in-normoglycemic-subjects-with-parental-history-of-type-2-diabetes-mellitusResearch Publish Journals (Publisher),
Website: www.researchpublish.co
The second part of the marrow of modern divinity. [electronic resource] : Touching the most plain, pithy and spiritual exposition of the Ten Commandments; the examination of the heart and life by them; the reason why the Lord gave them; and, the use that both unbelievers and believers are to make of them. Profitable for any man who either desires to be driven out of himself to Christ, or so to walk as that he may please Christ. In a dialogue, betwixt evangelista, a minister of the Gospel. Nomologista, a pratler about the law. And Neophytus, a young Christian. By E.F. author of the first part.
No full textE. F. = Edward Fisher; his authorship is sometimes disputed.Price on title page: Price Stitched 1 shil. sterl.2 reports submitted by E, one says [Edinburgh] the other [Scotland]. Roman sequence of pagination may have upper case charactersElectronic reproduction.English Short Title Catalog,Reproduction of original from Bodleian Library (Oxford)
Ethics as ritual: smoothing over moments of dislocation in biomedicine
Get PDFApplications of biomedical R&D currently imply substantial societal concerns. This paper explores, based on semi‐structured interviews with scientists in Norway, how biomedical researchers experience and tackle such concerns in their daily work. It shows how ritualised routine responses to dislocatory moments help maintain order in the daily work of the interviewed scientists; they do not address directly but instead smooth over concerns by a ritualised way of using ethics. This may foreclose substantive reflection and function as a stabiliser for ‘business as usual’. Overall, the current way of responding to concerns as described by the interviewees may contribute to a depoliticisation of important issues. The paper contributes to sociological work on ethics by linking it to recent discussions on Responsible Research and Innovation (RRI) and by the empirical research presented. The insights can also help improve science policies such as RRI.publishedVersion© 2018 The Author. Sociology of Health & Illness published by John Wiley & Sons Ltd on behalf of Foundation for SHIL. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License
Stratified users and technologies of empowerment: theorising social inequalities in the use and perception of diabetes self‐management technologies
Get PDFMedical technologies of various kinds play an increasingly important role in medical treatment, but may also increase health inequalities if they are primarily used by high-status patients. While many have problematised inequalities in the material access to medical technologies, differences in use and perception are also salient for explaining the relationship between medical technologies and health inequalities. This article attempts to theorise these inequalities by bringing health inequality research into dialogue with social constructivist perspectives on usertechnology relations. Based on qualitative interview data from a case study of the technological self-management of type 1 diabetes, I construct three clusters of technological practices and perceptions corresponding to three broad user types. These user types are then discussed in the context of patient empowerment and the promotion of the active, autonomous and self-reflective ‘expert’ patient in European health care systems. To the extent that they materialise and enforce institutional expectations which only the most resourceful patients will be able to live up to, medical technologies may serve to entrench and legitimate social inequalities in health and medical care. Research therefore needs not only to consider how medical technologies are distributed, but also their design and appropriation by users.publishedVersion© 2020 The Author. Sociology of Health & Illness published by John Wiley & Sons Ltd on behalf of Foundation for SHIL This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cite
The association between life course socioeconomic position and life satisfaction in different welfare states:European comparative study of individuals in early old age
Get PDFBACKGROUND: whether socioeconomic position over the life course influences the wellbeing of older people similarly in different societies is not known.OBJECTIVE: to investigate the magnitude of socioeconomic inequalities in life satisfaction among individuals in early old age and the influence of the welfare state regime on the associations. Design: comparative study using data from Wave 2 and SHARELIFE, the retrospective Wave of the Survey of Health, Ageing, and Retirement in Europe (SHARE), collected during 2006-07 and 2008-09, respectively.SETTING: thirteen European countries representing four welfare regimes (Southern, Scandinavian, Post-communist and Bismarckian).SUBJECTS: a total of 17,697 individuals aged 50-75 years.METHODS: slope indices of inequality (SIIs) were calculated for the association between life course socioeconomic position (measured by the number of books in childhood, education level and current wealth) and life satisfaction. Single level linear regression models stratified by welfare regime and multilevel regression models, containing interaction terms between socioeconomic position and welfare regime type, were calculated.RESULTS: socioeconomic inequalities in life satisfaction were present in all welfare regimes. Educational inequalities in life satisfaction were narrowest in Scandinavian and Bismarckian regimes among both genders. Post-communist and Southern countries experienced both lower life satisfaction and larger socioeconomic inequalities in life satisfaction, using most measures of socioeconomic position. Current wealth was associated with large inequalities in life satisfaction across all regimes.CONCLUSIONS: Scandinavian and Bismarckian countries exhibited narrower socioeconomic inequalities in life satisfaction. This suggests that more generous welfare states help to produce a more equitable distribution of wellbeing among older people.</p
Patients with neurological or psychiatric complications of COVID-19 have worse long-term functional outcomes: COVID-CNS-A multicentre case-control study
Get PDF\ua9 2025. The Author(s). It is established that patients hospitalised with COVID-19 often have ongoing morbidity affecting activity of daily living (ADL), employment, and mental health. However, little is known about the relative outcomes in patients with COVID-19 neurological or psychiatric complications. We conducted a UK multicentre case-control study of patients hospitalised with COVID-19 (controls) and those who developed COVID-19 associated acute neurological or psychiatric complications (cases). Among the 651 patients, [362 (55%) cases and 289 (45%) controls], a higher proportion of cases had impairment in ADLs (199 [68.9%] vs 101 [51.8%], OR 2.06, p < 0.0002) and reported symptoms impacting employment (159 [58.2%] vs 69 [35.6%] OR 2.53, p < 0.0001). There was no significant difference in the proportion with depression or anxiety between case and control groups overall. For cases, impairment of ADLs was associated with increased risk in female sex, age > 50 years and hypertension (OR 5.43, p < 0.003, 3.11, p = 0.02, 3.66, p = 0.04). Those receiving either statins or angiotensin converting enzyme (ACE) inhibitors had a lower risk of impairment in ADLs (OR 0.09, p = 0.0006, 0.17, p = 0.03). Patients with neurological or psychiatric complications of COVID-19 had worse functional outcomes than those with respiratory COVID-19 alone in terms of ADLs and employment. Female sex, age > 50 years, and hypertension were associated with worse outcomes, and statins or ACE inhibitors with better outcomes
Department of Error: Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000–17: analysis for the Global Burden of Disease Study 2017 (The Lancet (2020) 395(10239) (1779–1801), (S0140673620301148), (10.1016/S0140-6736(20)30114-8))
No full textReiner RC Jr, Hay SI. Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000–17: analysis for the Global Burden of Disease Study 2017. Lancet 2020; 395: 1779–801—In this Article, the author byline has been amended to Local Burden of Disease Diarrhoea Collaborators. This correction has been made to the online version as of June 4, 2020, and the printed version is correct
Posthospitalization COVID-19 cognitive deficits at 1 year are global and associated with elevated brain injury markers and gray matter volume reduction
Get PDF\ua9 The Author(s) 2024. The spectrum, pathophysiology and recovery trajectory of persistent post-COVID-19 cognitive deficits are unknown, limiting our ability to develop prevention and treatment strategies. We report the 1-year cognitive, serum biomarker and neuroimaging findings from a prospective, national study of cognition in 351 COVID-19 patients who required hospitalization, compared with 2,927 normative matched controls. Cognitive deficits were global, associated with elevated brain injury markers and reduced anterior cingulate cortex volume 1 year after COVID-19. Severity of the initial infective insult, postacute psychiatric symptoms and a history of encephalopathy were associated with the greatest deficits. There was strong concordance between subjective and objective cognitive deficits. Longitudinal follow-up in 106 patients demonstrated a trend toward recovery. Together, these findings support the hypothesis that brain injury in moderate to severe COVID-19 may be immune-mediated, and should guide the development of therapeutic strategies
