1,721,037 research outputs found

    Acute pulmonary embolism: Focus on the clinical picture

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    Acute pulmonary embolism (APE) is characterized by numerous clinical manifestations which are the result of a complex interplay between different organs; the symptoms are therefore various and part of a complex clinical picture. For this reason, it may not be easy to make an immediate diagnosis. This is a comprehensive review of the literature on all the various clinical pictures in order to help physicians to promptly recognize this clinical condition, remembering that our leading role as cardiologists depends on and is inffuenced by our knowledge and working methods

    Role of RAAS inhibition in preventing left ventricular remodeling in patients post myocardial infarction

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    Left ventricular remodeling after myocardial infarction has been identified as a predictor of adverse outcome and as a relevant therapeutic target. It has been shown that upregulation of the renin-angiotensin-aldosterone system (RAAS)* has an important role in the pathogenesis of cardiac remodeling. In this paper we summarize evidence on the role of the RAAS in the development of left ventricular remodeling and review major trials based on the addition of an RAAS inhibitor to standard therapy in the post myocardial infarction setting to prevent remodeling and improve outcome

    Quality, prices and production efficiency: an exploratory study of Italian wines with appellation of origin

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    Wine is a complex and highly differentiated product of a very wide and heterogeneous compartment, where quality plays an important role in determining demand. Wine production in Italy is unique in the world and important for all of its regions and its vineyards are placed in extremely different environments, from coastal plains to considerable altitudes and slopes. The Italian level of quality can be considered very high, since approximately 69% of wine production is characterized by Appellation of Origin (AO). The main purpose of this study is to evaluate the potential efficiency in production of Italian wines with Appellation of Origin, in terms of quality, prices and vine yields. Results of this study highlight the economic value generated annually by each declared hectare of vineyard, showing the “Top five wines”, allowing reflections that underline the strategic role of some factors, useful to create a high value production process

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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