32,495 research outputs found
Assyria: The Creation of a New Rural Landscape in the Heart of Assyria: Settlement, Irrigation Canals and Economic Growth in the Countryside around Nineveh
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Introduction / Introduzione
No full textThe article introduces the volume by tracing thirty years of research and discoveries made by the University of Udine and its partners in the ancient Near Eas
Il futuro è alle spalle. Causalità aristotelica e realismo sociologico
No full textLa proposta del “realismo sociologico” è offrire una alternativa alla perdita di realtà della cultura occidentale contemporanea. Si tratta di scoprire la “realtà della realtà” , senza perciò volere in nessun modo garantire l’ “infallibilità della sua conoscenza”. Solo distinguendo l’ontologia dall’epistemologia, l’essere dalla conoscenza dell’essere, è possibile “salvare” il riferimento ad una realtà indipendente dall’osservatore. Il realismo sociologico si presenta dunque come un modo di pensare capace di riproporre una ragione “aperta” e “sensibile alla verità”
Prognostic role of clusterin in resected adenocarcinomas of the lung
No full textPrognostic role of clusterin in resected adenocarcinomas of the lung.
Panico F, Casali C, Rossi G, Rizzi F, Morandi U, Bettuzzi S, Davalli P, Corbetta L, Storelli ES, Corti A, Fabbri LM, Astancolle S, Luppi F.
Source
Section of Respiratory Diseases, Department of Oncology, Haematology & Pulmonology, University of Modena and Reggio Emilia, Modena, Italy.
Abstract
RATIONALE:
Clusterin expression may change in various human malignancies, including lung cancer. Patients with resectable non-small cell lung cancer (NSCLC), including adenocarcinoma, have a poor prognosis, with a relapse rate of 30-50% within 5 years. Nuclear factor kB (Nf-kB) is an intracellular protein involved in the initiation and progression of several human cancers, including the lung.
OBJECTIVES:
We investigate the role of clusterin and Nf-kB expression in predicting the prognosis of patients with early-stage surgically resected adenocarcinoma of the lung.
FINDINGS:
The level of clusterin gradually decreased from well-differentiated to poorly differentiated adenocarcinomas. Clusterin expression was significantly higher in patients with low-grade adenocarcinoma, in early-stage disease and in women. Clusterin expression was inversely related to relapse and survival in both univariate and multivariate analyses. Finally, we observed an inverse correlation between Nf-kB and clusterin.
CONCLUSIONS:
Clusterin expression represents an independent prognostic factor in surgically resected lung adenocarcinoma and was proven to be a useful biomarker for fewer relapses and longer survival in patients in the early stage of disease. The inverse correlation between Nf-kB and clusterin expression confirm the previously reported role of clusterin as potent down regulator of Nf-kB
Diet, physical, and biochemical characteristics of children and adolescents with type 1 diabetes: relationship between dietary fat and glucose control.
No full textMaffeis C, Morandi A, Ventura E, Sabbion A, Contreas G, Tomasselli F, Tommasi M, Fasan I, Costantini S, Pinelli L. Diet, physical, and biochemical characteristics of children and adolescents with type 1 diabetes: relationship between dietary fat and glucose control. Background: Nutritional habits may significantly influence glycemic control and cardiovascular risk factors in youth with type 1 diabetes (T1D). Aims: To assess dietary intake, cardiovascular risk factors, and the association between diet composition and glycemic control in Italian youth with T1D. Methods: Subjects included 114 youth aged 6-16 yr with T1D receiving a routine treatment program with nutrition counseling and 448 controls. Cross-sectional measures included dietary intake, anthropometry, blood pressure, lipid profile, and, in children with diabetes, HbA1c. Results: In prepubertal children, BMI, subcutaneous skinfolds, the prevalence of overweight/obesity, and LDL cholesterol (LDL-CH) were significantly lower in patients than in controls, whereas HDL cholesterol (HDL-CH) was higher. Pubertal boys with T1D did not differ significantly from controls in either anthropometry or lipid profile. Pubertal girls with T1D had a higher BMI and higher triceps skinfolds than controls but not significantly different prevalence of overweight/obesity or lipid profile. Compared to controls, participants with T1D had a lower intake of lipids and simple carbohydrates, a higher ratio of unsaturated/saturated fats and fibre, and a dietary intake closer to the National Reference Dietary Intakes (RDIs). The odds of having an HbA1c higher than 7.5, adjusted for BMI, lipid, and fibre intake, increases by 53\% for every 1\% increase of energy intake from saturated fat in the diet and by 30\% for every year of duration of diabetes. Conclusions: Youth with T1D having regular nutritional counseling had a diet closer to RDIs than controls and not different cardiovascular risk factors. High saturated fatty acid intake was associated with poor blood glucose control
Lateral strength Of urm piers: comparison between codified criteria and in-plane test results
No full textThe lateral resistance represents one of the most significant wall parameters to be used in the seismic analyses for the design/assessment of masonry buildings. In this article, an investigation on in-plane lateral strength of URM piers has been proposed thorough a comparison between the results from codified criteria and the outcomes of several experimental in-plane cyclic tests on masonry walls. In this context, a new database collecting the results of in-plane cyclic tests on unreinforced masonry piers, carried out within different research projects, has been devel-oped. The database consists of walls with bricks and blocks with different masonry materials (clay, lightweight aerated concrete, AAC, calcium silicate), bed-and head-joint typologies, di-mensions, boundary conditions, vertical applied loads and horizontal loading history. This source of information of consistent and reliable test results represents a necessary step into the process of definition of shared rules in the European context.Accepted Author ManuscriptApplied Mechanic
From the Core of the Empire. New Archaeological Discoveries of the University of Udine in Ancient Assyria
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