8 research outputs found
L' arte della decorazione italiana : studiata sugli archi e i graffiti di Roma sul Palazzo di Caprarola e sulle targhe delle carte geografiche del Vaticano
illustrata in ordine alla storia e alle arti dal Genesio MorandiGeschenkexlibris-Etikette: ""Dieses Geschenk verdankt die Bibliothek der E.T.H. der Freigebigkeit von Dr. Ing. Aldo Müller St. Georgenstrasse 12, Winterthur - Es stammt aus dem Nachlass von Architekt Gustav Emil Müller 1844-1924" 002106137_0002 Exemplar der ETH-BI
Transcritical and zero-Hopf bifurcations in the Genesio system
Agraïments: The first author is supported by FAPESP Grant No. 2013/24541-0. Both authors are supported by CAPES Grant 88881.030454/2013-01 Program CSF-PVE.In this paper we study the existence of transcritical and zero--Hopf bifurcations of the third--order ordinary differential equation a b c x - x^2 = 0, called the Genesio equation, which has a unique quadratic nonlinear term and three real parameters. More precisely, writing this differential equation as a first order differential system in \R^
Transcritical and zero-Hopf bifurcations in the Genesio system
Agraïments: The first author is supported by FAPESP Grant No. 2013/24541-0. Both authors are supported by CAPES Grant 88881.030454/2013-01 Program CSF-PVE.In this paper we study the existence of transcritical and zero--Hopf bifurcations of the third--order ordinary differential equation a b c x - x^2 = 0, called the Genesio equation, which has a unique quadratic nonlinear term and three real parameters. More precisely, writing this differential equation as a first order differential system in \R^
Panorama des institutions d’art contemporain à Turin
Ces dernières années, la ville de Turin s’est consacrée au développement d’une politique culturelle visant le secteur de l’art contemporain. On a pu notamment assister à l’implantation de nouveaux sites d’exposition et à la mise en place de manifestations à vocation internationale. En ce sens, la politique culturelle de Turin apparaît comme un cas exemplaire d’instrumentalisation de l’art contemporain au service de la promotion de la ville sur la scène internationale et de la convergence entre les enjeux de cet art et le processus de mondialisation économique.The author is interested in the specific case of the city of Turin and in the expansion in recent years of its cultural policy towards the field of contemporary art; with among other things the creation of new exhibition venues, as well as international events. The city of Turin’s policy seems to be an exemplary case of contemporary art “instrumentalization” in the name of promotion of the city on the international scene. At the same time though, it is binding together the goals of contemporary art with the process of economic globalization
Investigações sobre doenças de Psittacideos
The present paper colligates the notions acquired in previous investigations, already published, and new observations upon diseases of the psittacidae, liable to be confused with psittacosis of parrots. The author calls attention to the indifference with regard to this question shown by investigators, even by those who dealt with the study of this disease on the occasion of the latest outbreak of psittacosis, in flagrant contrast with the researches upon the alterations induced by pathogenic agents of other diseases transmissible to man, when these agents pass through animals or when the latter are depositaries of the virus. This remark considerably enhances the importance of the presence paper from a hygienic and epidemiologic point of view, representing moreover a contribution to general knowledge and to veterinary medicine. The researches carried out since the appearance of the latest outbreak of psittacosis,-which occurred simultaneously with an epizooty in parrots lodged in aviary of the park of Agua Branca (Directory of Animal Industry of the State São Paulo)-led to the verification of the frequent existence in these animals of various diseases liable to be confused with psittacosis. These diseases are due to two kinds of pathogenic agents: virus and bacteria. In the first group there are to be found the diseases occasioned by the virus of human psittacosis, discovered by Western, Bedson and Simpson, and the disease me with in parrots coming from traders in S. Paulo. The infections by bacteria of the genus Salmonella and by those of other genera belong to the second group. As differential characters of the two infections due to virus, delineated on the strength of notions drawn from a detailed experimental study and from the literature on this subject, the following are given: ¹ Samples of our virus were sent, for comparison, to various investigators of psittacosis. Amongst them, Prof. M. Rivers acceded to our request; he found its nature to be different from that of the virus of psittacosis studiedby him. We are very much obliged to him for the attention he paid to this verification. Virus of psittacosis - Infectiousness: man, monkey, rabbit, mouse, hen, canary. Neurotropic affinity. Inclusions: small, protoplasmic. Exsiccation: the virus has good power of preservation. Symptoms: inactivity, drowsiness, frequent diarrhoea, oculo-nasal discharge and cough, coma. Duration: 4 to 5 days. Bodily lesions: congestion of intestines, splenomegaly. Virus of S. Paulo - Infects only psittacidae, particularly those of the genus Amazona. No localization in the nervous system. Large, nuclear. Is rapidly destroyed. Inactivity, inappetency, adynamia (drooping of the wings, indifference, leaning its beak against the bars of the cage in order not to fall down); profuse diarrhoea, of whitish stools, at times enterorrhagia; prolonged coma. 2 to 8 days. Foci of yellowish necrosis in liver, spleen and lung. At times, congestion of intestines. Characteristic features common to the two viruses.-They act in great dilutions, filter through tight candles though being partly retained, are preserved under glycerine or Bedson's solution, are stable at 55°C. heat and are destroyed by physical and chemical agents. Both virus diseases are very seldom met with in psittacidae: only once, amongst numberless sick parrots, the author met with a disease of the virus differring from that of psittacosis. This disease, greatly transmissible to man, ought to be more frequent, if it were common in parrots. On the contrary, bacteria cause diseases in these animals with great frequency, presenting variable characters, from a severe epizootic form, rapidly mortal, to ambulatory or silent forms, for the most part developing towards a cure or assuming a chronic character. Amongst the bacteria which cause the infection of this group the salmonellae predominate and amongst them the bacterium discovered by Nocard, as well as a species which in the course of this study is characterized under the name of Salmonella nocardi. The author believes that in the epizooty from which Nocard isolated his bacterium there was association of the virus-disease inducing the epizooty of that epoch in Paris with the bacterial disease, as must have happened in Argentina, where the disease was transmitted to man, and Santillan, according to Barros, isolated from the sick parrots bacteria of the genus Salmonella. The diseases of the two groups, that due to virus and that due to bacteria, are differentiated: Virus-diseases - Evolution: rapid, nearly always followed by death. Symptoms: sadness, profuse diarrhoea, of whitish stools, at times enterorrhagia, complete inappetency, adynamia, indifference, prolonged coma. Clinical forms: acute and subacute. Lesions: Foci of necrosis in liver and spleen without cellular reaction around the focus, yellow liver, multiple serositis. Presence of protoplasmic or nuclear granulations. Bacteriology: Complete lack or inconstant presence of bacteria in the organs and blood. Infectiousness of the organs and blood after filtration: positive. Bacterial diseases - Varies from one week to a month or more, not always fatal. Sadness, partial inappetency, tremblings, intensive thirst, mucous or mucosanguineous diarrhoea, lack of adynamia (reacts to stimulations and moves well at any time of the disease, though showing little disposition to locomotion), soiling of feathers. Frustrate, acute, subacute and chronic. Hepatic and intestinal cogestion, foci of necrosis in liver, spleen and lung with cellular reaction around the focus. Lack of granulations. Constant presence of bacteria in the organs and blood. Negative. The analysis of the litterature shows that the characteristic features of the diseases in parrots referred to parrot psittacosis, more frequently approach the bacterial diseases here described of these animals, a hypothesis which is reinforced by the observation of the greater frequency of infections..
Fluid, kinetic and hybrid approaches for neutral and trace ion edge transport modelling in fusion devices
Neutral gas physics and neutral interactions with the plasma are key aspects of edge plasma and divertor physics in a fusion reactor including the detachment phenomenon often seen as key to dealing with the power exhaust challenges. A full physics description of the neutral gas dynamics requires a 6D kinetic approach, potentially time dependent, where the details of the wall geometry play a substantial role, to the extent that, e.g., the subdivertor region has to be included. The Monte Carlo (MC) approach used for about 30 years in EIRENE [1], is well suited to solve these types of complex problems. Indeed, the MC approach allows simulating the 6D kinetic equation without having to store the velocity distribution on a 6D grid, at the cost of introducing statistical noise. MC also provides very good flexibility in terms of geometry and atomic and molecular (A&M) processes. However, it becomes computationally extremely demanding in high-collisional regions (HCR) as anticipated in ITER and DEMO. Parallelization on particles helps reducing the simulation wall clock time, but to provide speed-up in situations where single trajectories potentially involve a very large number of A&M events, it is important to derive a hierarchy of models in terms of accuracy and to clearly identify for what type of physics issues they provide reliable answers. It was demonstrated that advanced fluid neutral (AFN) models are very accurate in HCRs, and at least an order of magnitude faster than fully kinetic simulations. Based on these fluid models, three hybrid fluid-kinetic approaches are introduced: a spatially hybrid technique (SpH), a micro-Macro hybrid method (mMH), and an asymptotic-preserving MC (APMC) scheme, to combine the efficiency of a fluid model with the accuracy of a kinetic description. In addition, atomic and molecular ions involved in the edge plasma chemistry can also be treated kinetically within the MC solver, opening the way for further hybridisation by enabling kinetic impurity ion transport calculations. This paper aims to give an overview of methods mentioned and suggests the most prospective combinations to be developed.sponsorship: The paper presents a joint effort within the EUROfusion Theory and Advanced Simulation Coordination (E-TASC), task 'NGM' 2019-2020 and the related O-EIRENE HLST project. This work has been carried out within the framework of the EUROfusion Consortium and has received funding from the Euratom research and training programme 2014-2018 and 2019-2020 under Grant Agreement No. 633053. The views and opinions expressed herein do not necessarily reflect those of the European Commission. W. Van Uytven is funded by a PhD fellowship of the Research Foundation Flanders (FWO). Parts of the work were supported by the Research Foundation Flanders (FWO) under project Grant G078316N. (Euratom research and training programme 2014-2018|633053, Euratom research and training programme 2019-2020|633053, Research Foundation Flanders (FWO)|G078316N)status: Publishe
AUTS2-related Syndrome: Insights from a large European cohort
Abstract
Purpose:
AUTS2-related syndrome is characterized by developmental delay, autism spectrum disorder, and intellectual disability. From alternative promoters, AUTS2 encodes 2 distinct long and short isoforms encoding a putative transcriptional activator.
Methods:
Through a European collaborative study, we collected clinical and genotype data on the largest AUTS2-related syndrome cohort of 58 patients harboring genomic rearrangements or single-nucleotide variants (SNVs).
Results:
Pathogenic SNVs were recurrently found in individuals from different countries, suggesting mutational hotspots. Independent of the underlying defect at the AUTS2 locus, we observed that autistic behavior, hyperactivity, learning difficulties, and speech delay are common features of AUTS2-related syndrome. Among patients with SNVs, individuals carrying pathogenic variants affecting both longer and shorter AUTS2 transcripts showed a recognizable phenotype with microcephaly, brachycephaly, microretrognathia, broad nasal base, and anteverted nares. Behavioral disorders were more common in patients with variants affecting only the longer isoform. Arthrogryposis and stiff movements were only observed in patients with SNVs.
Conclusion:
This study provides a comprehensive clinical characterization of AUTS2-related syndrome, reveals few genotype-phenotype correlations, and suggests that the disruption of the 2 distinct AUTS2 transcripts has a different impact on the clinical phenotype.Abstract
Purpose:
AUTS2-related syndrome is characterized by developmental delay, autism spectrum disorder, and intellectual disability. From alternative promoters, AUTS2 encodes 2 distinct long and short isoforms encoding a putative transcriptional activator.
Methods:
Through a European collaborative study, we collected clinical and genotype data on the largest AUTS2-related syndrome cohort of 58 patients harboring genomic rearrangements or single-nucleotide variants (SNVs).
Results:
Pathogenic SNVs were recurrently found in individuals from different countries, suggesting mutational hotspots. Independent of the underlying defect at the AUTS2 locus, we observed that autistic behavior, hyperactivity, learning difficulties, and speech delay are common features of AUTS2-related syndrome. Among patients with SNVs, individuals carrying pathogenic variants affecting both longer and shorter AUTS2 transcripts showed a recognizable phenotype with microcephaly, brachycephaly, microretrognathia, broad nasal base, and anteverted nares. Behavioral disorders were more common in patients with variants affecting only the longer isoform. Arthrogryposis and stiff movements were only observed in patients with SNVs.
Conclusion:
This study provides a comprehensive clinical characterization of AUTS2-related syndrome, reveals few genotype-phenotype correlations, and suggests that the disruption of the 2 distinct AUTS2 transcripts has a different impact on the clinical phenotype
Predictive Application of Retrievable Waste Heat of the Cement Industrial Rotary Kiln on Solid Oxide Fuel Cells
本文提出一全新的技術觀念:利用目前現存之旋轉窯熱流場提供固態氧化燃料電池(SOLID OXIDE FUEL CELL, SOFC)所需之高溫操作環境。現今的新型管式SOFC設計 (TSOFC) 更適合於旋轉窯之安裝與操作,為數種燃料電池中最為適與汽電共生或與焚化爐結合的類型。
故本文以其為研究對象,合理地假設並評估其安裝的可行性,並發現妥善安排的燃料電池模組共可產出達39.59MW的電能。
本實驗並採用計算流體力學軟體FLUENT之有限體積分析法解工業用旋轉窯焚化爐窯體內之熱流場、向量場、與物質反應的偏微分方程式,以反應操作模式中燃燒所需之過剩空氣量與溫度、旋轉爐之旋轉速度為主要參數,模擬燃燒氣體熱流場與旋轉窯壁之熱傳模式。模擬結果與實際現場量測所得之溫度數值作相互比對,以進行各不同之燃燒反應參數在流場顯影之探討,最後並依照其燃燒熱流場及窯壁內部溫度之分佈預測,進行固態氧化物燃料電池於旋轉窯爐床安裝之可行性探討。When meeting the shortage of fossil fuels and the coming era of hydrogen energy, fuel cell energy emerged to be a promising technology in energy utilization in the future.
Developed to work at 800 to 1,000 degree Celsiusand and up to 15 atm (tested by Ontario Hydro Technology), solid oxide fuel cells (SOFCs) can generate the maximum power output among all types of fuel cells. However, when operating the SOFCs, great amount of fossil fuel is actually consumed in order to meet their high-temperature demand. High amount of secondary pollutants are expelled accordingly.
A possible brand new idea is thus proposed in this paper—a state-of-the-art tubular SOFC (TSOFC) can be installed either in the three dimensional heat flow field inside the cement industrial rotary kiln incinerator (RKI, located in Kaohsiung, Taiwan) or within its refractory layer where high temperature environment sustains around the clock when operating for the cement production. In this paper, simulation of the heat flow field and species remained after combustion in this kiln incinerator is achieved with the help of modern computer aided engineering (CAE) tool.
Suitable manipulating regions are to be found and predicted via the commercially available CFD code FLUENT. Parameter of excess air values are the primary variable, the detailed interior heat flow field and the heat transfer model in the kiln shell are the secondary variables for evaluating the installation of SOFCs into rotary kilns.
Before going on this study, kinetic parameters are parametrically varied and finite volume method (FVM) is introduced to solve the heat flow field and the visualization of the three dimensional flame structure is performed. Meanwhile, simulation of temperature results is compared with on-site field experiments and the installation possibilities of the SOFC on the rotary kiln incinerator can be reasonably predicted and assuredAbstract in Chinese------------------------------------------------------------1
Abstract in English------------------------------------------------------------2
Nomenclature-------------------------------------------------------------------3
Table of Contents--------------------------------------------------------------5
List of Figures ----------------------------------------------------------------7
List of Tables --------------------------------------------------------------------9
Chapter 1 Introduction-----------------------------------------10
Chapter 2 Literature Review-----------------------------------------11
Chapter 3 Physical Descriptions-------------------------------------13
3.1. Solid Oxide Fuel Cell-----------------------------------------------13
3.2. Cement Industry----------------------------------------------------17
3.2.1. Rotary Kiln-------------------------------------------------------17
3.2.2. Cement Formation Process------------------------------------18
3.2.3. Combustion Fuels of the Rotary Kiln-------------------------19
Chapter 4 Results and Discussions------------------23
4.1. Numerical Approach of the Kiln Incinerator----------------23
4.2. Installation Possibility inside the Furnace Body-----------28
4.3. Installation Possibility inside the Refractory Layer around the Kiln Shell-----30
4.4. Power Estimation and Possible Strategy for Installing SOFC Stacks-----33
Chapter 5 Conclusion Remarks--------------------------------36
References-------------------------------------------------------37
Appendix -------------------------------------------------------------40
Author Resume-----------------------------------------------------5
