1,721,249 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Pharmaceutically active compounds and methods for use
No full textNew fused thiophene compounds are provided and methods of using those conmpounds for a variety of therapeutic indications. Compounds of the invention are particulary useful for treatment of neuropathic pai
Preparation of nucleosides as adenosine A3 receptor agonists
No full textNucleosides I, wherein Ar is aryl; R and R1 are independently H, alkyl, aryl, heteroaryl, alkenyl, cyclo-alkenyl, cycloalkyl, alkynyl; R and R1 together with the nitrogen atom to which they are attached form an optionally substituted satd. or unsatd. 3 to 20-membered ring system having a single ring or multiple condensed rings which may optionally contain 1 to 4 addnl. heteroatoms selected from O, S and N; provided that R and R1 are not both H when Ar is Ph and the sulfonamide group is located at the 4-position; or, either R or R1 is not pyridin-2-yl, pyrimidin-2-yl or 5-methyl-isoxazol-3-yl when the other is hydrogen, Ar is Ph and the sulfonamide group is located at the 4-position; were prepd. and tested as adenosine A3 receptor agonists. Accordingly, nucleosides I may be employed for treatment of behavioral depression, cerebral ischemia, hypotension, chem. induced seizures, inflammatory diseases, asthma, and cancer diseases expressing the adenosine A3 receptor. Thus, nucleoside II was prepd. and tested as adenosine A3 receptor agonist
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Allosteric modulators of the A1 adenosine receptor
No full textTitle compd. I [R1 = H, (un)substituted alkyl, aryl or cycloalkyl; R2, R3 and R4 independently = H, halo, OH, NO2, CN, (un)substituted alkyl, aryl, cycloalkyl or alkoxy; Q = (un)substituted piperidinyl, azepinyl, 5-membered spirocyclic ring, etc.], and their pharmaceutically acceptable salts, are prepd. and disclosed as allosteric modulators of the A1 adenosine receptor and, thus, may be employed for the treatment of conditions mediated by the A1 adenosine receptor. E.g., II was prepd. and demonstrated an IC50 value of about 100 nM in a functional assay measuring the cAMP level in CHO cells expressing the human A1-adenosine receptor. As allosteric modulators of the A1 adenosine receptor, I should be prove useful for treatment of pain, in particular, chronic pain such as neuropathic pain; cardiac disease or disorder such as cardiac disarrhythmias, e.g., peroxysmal supraventricular tachycardia, angina, myocardial infarction and stroke; neurol. disease or injury; sleep disorder; epilepsy; and depression
Patients entered into MRC AML trials are biologically representative of the totality of the disease in the UK
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