1,721,437 research outputs found
Nur-i-Afshan V.12 no.19 May 1908
No full textContents: Editorial notes - O Christ of God, thy life divine [Poetry] by Moore, Stephen - A Universal problem [Article] by Hasler, J. I. - A moslem priest pointing to Christ - Telegrams [Letter]
This volume of Nur-i-Afshan published weekly on Fridays from Ludhiana
The development of small molecule transmembrane anion transporters for the treatment of disease
No full textWithin this thesis novel receptors capable of binding and facilitating the transmembrane transport of biologically relevant anions are reported. Molecules based on the diindolylurea and tris(2-aminoethyl)amine scaffolds are described and their anion binding properties in both solution and in the solid state are reported. Inspired by the high affinities for oxo-anions measured for these molecules in polar solvent mixtures, the anion transport properties of structurally simple ureas and thioureas were studied. The high Cl-/NO3 - and Cl-/HCO3 - antiport activity observed with some of the thiourea compounds led to the development of more ‘drug-like’ transporters containing trifluoromethyl substituents. Fluorination of the transporter scaffold in this manner enhanced the lipophilicity and increased the acidity of the NH hydrogen-bond donor groups, leading to improvements in both anion affinity and transport activity. This work ultimately produced compounds capable of facilitating ion transport in vitro.A series of bisurea compounds based on the ortho-phenylenediamine scaffold are reported as potent ion transporters, capable of facilitating a range of ion transport processes. The introduction of electron withdrawing substituents was found to increase transporter activity. Of particular note is a para-nitrophenyl functionalised bisurea that facilitates chloride transport at a loading of 0.1 mmol % (with respect to lipid), the lowest loading of a synthetic mobile carrier to facilitate anion transport reported to date.Dual host systems for both M+/Cl- symport (M = Na, K or Rb) and Cl-/HCO3 - antiport are also described. By using different transporters to facilitate each uniport pathway in these coupled transport processes, it was possible to achieve enhanced ion transport rates. Remarkably, this is the first reported example of a dual host approach towards anion antiport
Audit in ultrasound: An introduction and overview
No full textThis article highlights the importance of clinical audits within ultrasound and provides an overview of how audits can guide high-quality clinical care and lead advanced practice within Ultrasound. We outline the who, what when and where of audit and how it can be used in contemporary medicine. Utilising the frameworks within the United Kingdom from the British Medical Ultrasound Society and others as well as drawing from personal experience the authors demonstrate practical examples of audits that have improved the quality of care within the United Kingdom and lead the way for Advanced Practitioner roles where individuals undertake interventional procedures such as Fine Needle Aspirations. The aim of this articles is to demonstrate how Sonographers can take their audits forward and implement the clinical environment
BMUS journal club on Twitter: An analysis of the first #BMUS_JC discussions
No full textIntroduction: Journal clubs have evolved over recent years within healthcare to encourage continuing professional development. More recently, there has been a move from face-to-face group meetings to virtual groups utilising social media platforms. This article aims to explore the discussions and narrative following the inaugural BMUS journal club, highlighting the key discussions and themes from the participants and to provide a narrative for the future of ultrasound continuing professional development. Methods: The August 2020 journal club chat was focussed on the article featured in Ultrasound: “Sonographers’ level of autonomy in communication in Australian obstetric settings: Does it affect their professional identity?” by Thomas et al. Data consisting of Twitter correspondence were extracted and analysed from the advanced search function on Twitter using #BMUS_JC thread. An initial review ensured related content was included. A second review and semantic thematic analysis was then conducted on the 123 tweets. Results: In total, seven overall themes were identified between the three sub-threads within the journal club discussions. Those participating in the Twitter discussion recognised the limitations and barriers for communicating results to patients, acknowledging that training, support and regulatory involvement is required for sonographers to change practice locally and internationally. Conclusion: The group discussions on Twitter highlight the ongoing issues for sonographers’ professional identity worldwide. Furthermore, our analysis echo other contemporary studies which indicate that Twitter journal clubs act as a fruitful and dynamic source of continuing professional development, particularly in an era where social distancing is encouraged. The outcomes of the first BMUS journal club support the wider evidence that online journal clubs can provide a successful platform for professional discussion and debate.</p
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
FIGURES 5–10 in Aphelocheirus (s. str.) bruneiensis sp. n., a new benthic water bug (Hemiptera: Heteroptera: Aphelocheiridae) from Brunei, and a key to Bornean Aphelocheirus
No full textFIGURES 5–10. Aphelocheirus bruneiensis sp. n., holotype, male. (5) Mesosternal carina (mstc) and propleuron (ppl), ventrolateral (slightly caudal) aspect. (6) Genitalia, dorsal aspect, after removing the parameres: aed - mainpiece of aedeagus with bulbous outgrowths on both sides; lpa – left parandrium; pyg – pygophore, rpa – right parandrium. (7, 8) Left paramere, approximately dorsal and ventral aspects. (9, 10) Right paramere, approximately ventral and dorsal aspects.Published as part of Zettel, Herbert, Lane, David J. W. & Moore, Stephen, 2008, Aphelocheirus (s. str.) bruneiensis sp. n., a new benthic water bug (Hemiptera: Heteroptera: Aphelocheiridae) from Brunei, and a key to Bornean Aphelocheirus, pp. 61-68 in Zootaxa 1920 on page 64, DOI: 10.5281/zenodo.18468
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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