4,840 research outputs found

    Position paper: management of perforated sigmoid diverticulitis

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    Over the last three decades, emergency surgery for perforated sigmoid diverticulitis has evolved dramatically but remains controversial. Diverticulitis is categorized as uncomplicated (amenable to outpatient treatment) versus complicated (requiring hospitalization). Patients with complicated diverticulitis undergo computerized tomography (CT) scanning and the CT findings are used categorize the severity of disease. Treatment of stage I (phlegmon with or without small abscess) and stage II (phlegmon with large abscess) diverticulitis (which includes bowel rest, intravenous antibiotics and percutaneous drainage (PCD) of the larger abscesses) has not changed much over last two decades. On the other hand, treatment of stage III (purulent peritonitis) and stage IV (feculent peritonitis) diverticulitis has evolved dramatically and remains morbid. In the 1980s a two stage procedure (1st - segmental sigmoid resection with end colostomy and 2nd - colostomy closure after three to six months) was standard of care for most general surgeons. However, it was recognized that half of these patients never had their colostomy reversed and that colostomy closure was a morbid procedure. As a result starting in the 1990s colorectal surgical specialists increasing performed a one stage primary resection anastomosis (PRA) and demonstrated similar outcomes to the two stage procedure. In the mid 2000s, the colorectal surgeons promoted this as standard of care. But unfortunately despite advances in perioperative care and their excellent surgical skills, PRA for stage III/IV diverticulitis continued to have a high mortality (10-15%). The survivors require prolonged hospital stays and often do not fully recover. Recent case series indicate that a substantial portion of the patients who previously were subjected to emergency sigmoid colectomy can be successfully treated with less invasive nonoperative management with salvage PCD and/or laparoscopic lavage and drainage. These patients experience a surprisingly lower mortality and more rapid recovery. They are also spared the need for a colostomy and do not appear to benefit from a delayed elective sigmoid colectomy. While we await the final results ongoing prospective randomized clinical trials testing these less invasive alternatives, we have proposed (based primarily on case series and our expert opinions) what we believe safe and rationale management strategy

    Naxwaha Sifayneed ee Afsoomaaliga: mugga kowaad (mi): Ereyeynta

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    Qoraagu wuxuu buuggan ku lafagurayaa qaybaha hadalka ee Af-soomaaliga, gaar ahaan xagga sarfaha ereyga.In questo testo, l'autore presenta un'analisi relativa alle parti del discorso della lingua somala, con un particolare focus sulla morfologia.In this text, the author presents an analysis of the parts of speech of the Somali language, with a particular focus on morphology

    Fundamental view of the outcomes of entrepreneurship education

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    The research paper presents a holistic framework of the outcomes of entrepreneurship education (EE) at educational and socio-economic levels. Employing the general scientific research methods, monograph and logical construction, the author investigates the fundamental origins of the European Competence Framework for entrepreneurial learning and identifies a scientific justification for its implementation. This work is also the first to exploit an integral view of entrepreneurship as a combination of employability, intrapreneurship and venture creation – for measuring the impact of entrepreneurship education, and to set linkages between learning outcomes in real life and educational settings. The target audiences for this paper include entrepreneurship educators, researchers and EE decision-makers. </p

    Java EE and Spring Platform Comparison in Web Application Development

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    Java EE un Spring ir populārākās Java tīmekļa lietotņu izstrādes platformas. Vēsturiski Java EE platformas sākotnējās versijas sarežģītā izstrādes procesa un resursu patēriņa dēļ izstrādātāju vidū iemantoja "smagsvara" platformas slavu. Kā alternatīva "vieglā svara" platforma tika radīta Spring platforma. Laika gaitā Java EE tika uzlabota, un platformas jaunākajās versijās izstrādes procesa sarežģītība ir mazinājusies. Darbā tiek apskatītas Java EE 6 un Spring 3 platformu piedāvātās iespējas un analizēta to funkcionalitāte. Izmantojot autora izstrādātas lietotnes, tiek testēta un analizēta platformu veiktspēja. Noslēgumā tiek doti ieteikumi platformas izvēlē atkarībā no realizējamā projekta specifikas.Java EE and Spring are most popular Java web application platforms. Early versions of Java EE platform had complicated development process and high resource usage so in developer community it was called "heavy-weight". Spring platform emerged as an alternative "light-weight" platform. Later Java EE was updated and development complexity was decreased. Paper describes features of Java EE 6 and Spring 3 platform and analyses platform functionality. Performance of both platforms is tested using applications developed by author. In conclusion author gives recommendations for platform choice depending on project characteristics
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