54 research outputs found
iBooks Author: Potential, Pedagogical Meanings, and Implementation Challenges
No full textThis article discusses Apple’s iBooks Author, an application intended for textbook writers and publishers to create e-textbooks. This article provides insight on why IBA will change how we teach and learn as well as IBA’s potential, controversial issues, pedagogical meanings, and implementation challenges of using it as a classroom textbook. The article includes lessons learned from the leading countries in implementing e-textbooks in the classroom, such as South Korea and Malaysia
Apple’s iBooks Author
No full textThis chapter discusses Apple’s iBooks Author, a brand-new Mac application intended for textbook writers and publishers to create e-textbooks. This chapter provides insight on why IBA holds a prominent place in the field of education and will change our classroom landscape, that is, how we teach and learn. The main purpose of this chapter is to explore IBA’s potential, possible controversial issues, pedagogical meanings, and implementation challenges of using it as a classroom textbook. The chapter includes lessons learned from the leading countries in implementing e-textbooks in the classroom, such as South Korea and Malaysia
Hydrogen production by water reduction on Si photocathode coupled with Ni 2 P
No full textWhile searching for an efficient, non-noble, earth-abundant catalyst for the hydrogen evolution reaction (HER), we synthesized hexagonal dinickel phosphide with different nanostructures using solvothermal phosphidation. Coupled atop p-type Si, this catalyst performed as a p-n heterojunction photocathode assembly and the performance varied when under different electrolyte media. Apart from changing the surface morphology, Ni 2 P was crystallized with an increase in the Ni δ+ /Ni 2+ ratio as the phosphidation temperature gradually increased. A systematic evaluation of the water splitting reaction shows that a very small amount of catalyst (>85% transmittance for the catalyst layer) exhibits a photocurrent of −10 mA cm −2 with a positive applied potential of 0.05 V versus reversible hydrogen electrode under simulated solar irradiation of AM 1.5G. We discuss the substantial charge transfer process at the depletion layer of the electrode/catalyst and the catalyst/electrolyte interface. Mott–Shottky analysis showed a shift in the flat band potential for Ni 2 P, which reveals the underlying mechanism for the role of the p-n junction for enhanced photoelectrochemical cell performance. © 2019 Hydrogen Energy Publications Lt
KDS2010, a Newly Developed Reversible MAO-B Inhibitor, as an Effective Therapeutic Candidate for Parkinson’s Disease
No full text© 2021, The Author(s).Monoamine oxidase-B (MAO-B) is a well-established therapeutic target for Parkinson’s disease (PD); however, previous clinical studies on currently available irreversible MAO-B inhibitors have yielded disappointing neuroprotective effects. Here, we tested the therapeutic potential of KDS2010, a recently synthesized potent, selective, and reversible MAO-B inhibitor in multiple animal models of PD. We designed and synthesized a series of α-aminoamide derivatives and found that derivative KDS2010 exhibited the highest potency, specificity, reversibility, and bioavailability (> 100%). In addition, KDS2010 demonstrated significant neuroprotective and anti-neuroinflammatory efficacy against nigrostriatal pathway destruction in the mouse MPTP model of parkinsonism. Treatment with KDS2010 also alleviated parkinsonian motor dysfunction in 6-hydroxydopamine-induced and A53T mutant α-synuclein overexpression rat models of PD. Moreover, KDS2010 showed virtually no toxicity or side effects in non-human primates. KDS2010 could be a next-generation therapeutic candidate for PD.11Nsciescopu
How a Once-rejected Grant Proposal Was Later Funded by The State of Georgia
No full textThe article chronicles how a grant proposal rejected a year earlier turned into an approved proposal. This article discusses what the primary author learned through this grant-writing process and what major themes emerged as successful variables to achieve the state grant. In other words, we will examine how the accepted proposal was written differently from the rejected proposal
Cognitive deficits among older adults with schizophrenia
Full text linkThis study examines the cognitive profiles of older adults with schizophrenia and/or schizoaffective disorders indexed by intelligence quotient (IQ) and the Montreal Cognitive Assessment (MOCA). Of our participants, 39% exhibited cognitive impairment and results suggest that the nonverbal deficit was greater than the verbal deficit
Coping Together: Collective Self-Regulation in a Web-Based Course
No full textEditors’ Introduction This chapter examines the challenges facing the online learner, particularly the self-directed learner. The author suggests that the most successful online learners adopt the skills of “strategic learning”; this is characterised by having developed high levels of self-regulation and having the ability to consistently deploy these skills. She points to communal factors as being a key determinant in the development of self-regulating strategies through modelling of peers and the instructor and through heightened self-awareness of their own self-regulation. The chapter reports on the findings from a learning design that transformed her online class into a “community of survival”; the detailed findings compare and contrast individual and collective self-regulation strategies, and from this emerges a set of guiding principles that learning designers can use to bring a sharper focus on the promotion of self-regulated learning strategies
Forecasting Sales and Price for Existing Single-Family Homes: A VAR Model with Error Correction
Full text linkIn this paper we forecast demand for existing single-family housing in the United States. We first find that sales volume (sales) and median sales price (price) have unit roots. We then find that sales and price are cointegrated. We develop a vector autoregressive (VAR) model with error correction to further examine the causality between sales and price. We find that there exists a bidirectional causality relationship between sales and price. Price affects sales significantly and sales affects price weakly. With the VAR model we then forecast sales and price for existing single-family housing during the period 1991 to 1994 by using a recursive method. We find that our predictions for sales and price fit the actual data well.
Culture Considered Approaches to Design and Develop Teacher Professional Development in Ethiopia
No full textProfessional Development for Technology Integration Into Differentiated Math Instruction
No full textTo make a connection between pedagogy and technology in teaching, this chapter will explore whether or not a professional development design and practice, whose aim is to help teachers use technology for personal purposes, readily translates into the ability to effectively teach and learn with technology. Adopting a conceptual framework known as self-efficacy beliefs and TPACK, or technological pedagogical content knowledge (Mishra & Koehler, 2006), this chapter discusses the design of a professional development model, the goal of which is increasing the critical attribute of the successful professional development: self-efficacy. In an effort to provide empirical knowledge to support this design, this chapter further showcases a faculty member's approaches to connecting technology and pedagogy using the TPACK approach, while implementing a model designed to improve teachers' self-efficacy. Implications and guidelines for developing teachers' self-efficacy, through activities during the professional development workshop, are discussed. </jats:p
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