1,796 research outputs found
Cut-elimination, substitution and normalisation
No full textDate of Acceptance: 01/2015We present a proof (of the main parts of which there is a formal version, checked with the Isabelle proof assistant) that, for a G3-style calculus covering all of intuitionistic zero-order logic, with an associated term calculus, and with a particular strongly normalising and confluent system of cut-reduction rules, every reduction step has, as its natural deduction translation, a sequence of zero or more reduction steps (detour reductions, permutation reductions or simplifications). This complements and (we believe) clarifies earlier work by (e.g.) Zucker and Pottinger on a question raised in 1971 by Kreisel.Peer reviewe
I remember teaching English at Seabrook
No full textIn this "I remember" memoir, Isabell Waugh, a former teacher at Seabrook, compares and constrasts the different groups of students she taught. She remembers that native-born American teenagers tended to be more concerned with athletics and social activities, than academic matters. In comparison, Estonian and Japanese parents did not tolerate low academic performance, so students from the two groups often competed intensely with each other for academic achievement and recognition. Isabelle recalls that the Estonians were, in general, more sophisticated and better educated. Most of the children knew 3-5 languages, and were more advanced in math and science. She sensed that some Estonian parents felt that their homes at Seabrook were temporary, and that they would be returning to Estonia at some point. The Seabrook Educational and Cultural Center has been soliciting current and past residents of Seabrook Farms for an "I remember" project. Residents are asked to create narratives regarding their experiences at Seabrook Farms. These memories help preserve the history and multi-cultural heritage of Seabrook Farms
Isabelle Bell to Susan Niemcewicz, December 23, 1800
No full textIsabelle Bell wrote to Susan U. Niemcewicz in Elizabethtown, New Jersey. Bell expressed her disappointment in not receiving a line from Susan. She sent Bell Lucretia Rephans subscription epistle, but Susan refrained from writing a letter to her. Bell did not execute any of Susan’s commissions in New York because her time there was short. Miss Resham heard that Mr. B Livingston told his sister, Mrs. J. Livingston that he would offer Bell a salary to live in his house and take charge of his children’s education. Asked if Susan what she thought of her being an author and if Susan would subscribe to a small volume that may have the good fortune to rival the poems of the immortal Scarron.https://digitalcommons.kean.edu/lhc_1800s/1143/thumbnail.jp
Interviews with Carl T. Bode, Isabelle Fritschen, Joseph H. Hirt, Mary G. Hirt, and Minnie Campbell
No full textInterviews with Carl T. Bode, Isabelle Fritschen, Joseph H. Hirt, Mary G. Hirt, and Minnie Campbell. The recording includes a variety of German-language songs. The last half of the recording is dedicated to Minnie Campbell telling about her time working for Mother Bickerdyke. The first few minutes of the recording are missing. 00:00:13 - Song, The Messenger Bird sung by Joseph H. Hirt and translated by Isabelle Fritschen 00:01:35 - Song, Birdie in the Window, sung by Mary Gertrude Hirt 00:02:59 - Story of Peter John Thielen\u27s experience in the Franco-Prussian War told by Joseph Hirt 00:05:27 - Grandfather\u27s experience with wild cattle told by Isabelle Fritschen 00:07:31 - Carl T. Bode introduction 00:08:46 - Nursery rhyme about hands 00:09:09 - The Cuckoo and the Donkey 00:09:42 - Sleep Baby Sleep 00:10:24 - Golden Evening Sun 00:11:00 - Beautiful Moon 00:12:10 - My Homeland 00:13:50 - Minnie Campbell Introduction 00:14:05 - Experiences as Mother Bickerdyke\u27s secretary 00:14:35 - Mother Bickerdyke\u27s 81st birthday celebration in Bunker Hill, KS 00:19:59 - Mother Bickerdyke\u27s portrait 00:23:55 - How Lydia Foster, Mother Bickerdyke\u27s Black maid came to live with her. 00:26:34 - Mother Bickerdyke\u27s death 00:29:34 - Mother Bickerdyke\u27s burial in Galesburg, Illinois 00:30:28 - Working for Mother Bickerdyke 00:34:01 - Going to School as a student of James Bickerdyke, Mother Bickerdyke\u27s son 00:35:26 - Decline of Bunker Hill, KS 00:37:15 - Russell stealing the county seat from Bunker Hill 00:38:09 - Closing of the Dorrance, KS bank 00:39:00 - Mother Bickerdyke\u27s personality 00:42:34 - Experience with Nina Brown Baker author of Cyclone in Calico 00:48:24 - Mother Bickerdyke Home for Widows and Children in Ellsworth, KS 00:51:13 - Post scripthttps://scholars.fhsu.edu/sackett/1014/thumbnail.jp
Formalization of Isabelle Meta Logic in NuPRL
No full textNuPRL and Isabelle are two general purpose theorem provers. Both of them are based on a version of Constructive Higher Order Type Theory. In an earlier work the author has proposed an informal semantics of Isabelle Meta Logic in an extension of NuPRL Type Theory. An automated converter, based on this semantics, has been developed, that translates Isabelle theorem statements into NuPRL. This work presents a formalization of the above semantics in NuPRL. It starts with a deep embedding of Isabelle type and term syntax into NuPRL Constructive Type Theory. Next, two internal NuPRL functions are defined. One of them maps Isabelle types into NuPRL types and the other maps Isabelle terms into elements of appropriate NuPRL types. These two functions provide an interpretation of Isabelle in NuPRL. Finally, interpretations of all Isabelle Meta Logic rules are proven as theorems in some classical extension of NuPRL Type Theory. This formalization is aimed to provide a more secure foundation for the interaction between two systems
Domestic exposure to indoor air chemical pollutants : modeled exposure related to respiratory health effects in infancy : findings from the PARIS (Pollution and Asthma Risk an Infant Study) birth cohort
No full textProblématique : La qualité de l’air intérieur est devenue une préoccupation majeure de santé publique, en raison du temps passé à l’intérieur des locaux et de la diversité des contaminants biologiques et des polluants chimiques présents. Objectifs : Il s’agit de renseigner et de modéliser l’exposition domestique à des polluants chimiques retrouvés dans l’air intérieur et d’en étudier le lien avec la morbidité respiratoire au cours de la première année de vie des nouveau-nés de la cohorte PARIS (Pollution and Asthma Risk : an Infant Study). Méthodes : À 1, 3, 6, 9 et 12 mois, des questionnaires sanitaires sont adressés aux parents pour renseigner la survenue des infections des voies respiratoires et des symptômes évocateurs d’asthme (sifflements, toux sèche nocturne, etc.). Des questionnaires environnementaux sont envoyés en parallèle pour documenter le cadre et le mode de vie des enfants. Pour pallier l’imprécision résultant d’une évaluation de l’exposition aux polluants de l’air intérieur par simple questionnaire, des investigations environnementales complémentaires ont été conduites, à 1, 6, 9 et 12 mois, au domicile d’un échantillon aléatoire de 196 nouveau-nés de la cohorte PARIS et dans des crèches parisiennes fréquentées par ces enfants. Les données issues des mesurages domestiques répétés ont été confrontées aux données recueillies par questionnaires afin d’établir des modèles prédictifs s concentrations domestiques annuelles de polluants. Ces modèles ont ensuite été appliqués à l’ensemble des logements fréquentés par les enfants de la cohorte afin de les classer au regard de leur exposition domestique annuelle pour étudier l’impact sanitaire de cette exposition. Résultats : Les modèles prédictifs des concentrations mesurées ont permis d’identifier les déterminants des niveaux de formaldéhyde, de dioxyde d’azote, de toluène et de tétrachloroéthylène : les sources continues et leur caractère récent (panneaux de particules, parquet vitrifié, stratifié, flottant et peinture), les sources discontinues (combustion et proximité au pressing) et les paramètres d’aération et de ventilation conditionnant l’entrée ou la sortie du polluant selon leur origine dominante. Au cours de la première année de vie, près d’un enfant sur deux présente une infection des voies respiratoires basses, 14,8 % une toux sèche nocturne. Concernant l’impact sanitaire de l’exposition aux polluants chimiques, après ajustement sur l’ensemble des facteurs de risque, seule l’exposition domestique au formaldéhyde majore la survenue des infections et plus particulièrement des infections sifflantes. L’exposition au formaldéhyde est aussi associée à la toux sèche nocturne et plus particulièrement chez les enfants sans antécédents parentaux d’allergie. Conclusion : Une exposition domestique aux polluants chimiques de l’air intérieur, tels que le formaldéhyde, peut être associée à la morbidité respiratoire du jeune enfant. Ces résultats viennent appuyer les mesures prises par les pouvoirs publics concernant les émissions des matériauxThere is a growing public health concern about indoor air quality due to the time spent indoors and the presence of numerous biological and chemical pollutants. Aims: To assess indoor chemical pollutant levels, to model domestic exposure and to examine the impact of indoor chemical pollutants on the respiratory health of infants from the PARIS birth cohort, during their first year of life. Methods: Multiple self-administered questionnaires were used to gather information from parents about respiratory infections and asthma-like symptoms (wheezing, nocturnal dry cough. . . ) in their infants at ages 1, 3, 6, 9 and 12 months. Details about home characteristics and family living conditions were also collected by phone interview when the child was 1 month old, and mailed questionnaires captured changes at 3, 6, 9 and 12 months. Pollutant air sampling (aldehyde, volatile organic compound, nitrogendioxide and nicotine) were conducted at 1, 6, 9 and 12 months in the bedrooms of a subset of randomly selected 196infants. Repeated pollutant measurements were joined with interview and questionnaire information to construct annual pollutant exposure models for all infants. Furthermore, an environmental investigation was performed in Parisian child day care centers to document chemical exposure levels. Results: Formaldehyde, toluene, nitrogen dioxide and perchlororethylene level determinants: continuous sources (particleboard, varnished parquet floor, wall coating), discontinuous sources (combustion, dry cleaning facilities) and aeration parameters were identified. At one year, around half of babies experienced at least one lower respiratory infection, and nearly half of those infections included wheezing, 14,8 % of babies suffered from a nocturnal dry cough. After known risk factors were considered, lower respiratory infections were associated with estimated formaldehyde levels, and formaldehyde exposure is also related to nocturnal dry cough, especially in infants without parental history of allergy. Conclusion: This study shows that formaldehyde exposure in early life is associated with respiratory health in infants, promoting public actions regarding emissions from material
Security modeling and correctness proof using Specware and Isabelle
No full textSecurity modeling is the foundation to formal verification which is a core requirement for high assurance systems. This thesis explores how security models can be built in a simple and expressive manner using the Metaslang specification language in Specware. The models are subsequently translated, via the Specware to Isabelle Interface, to be proven for correctness in Isabelle which is a generic, interactive theorem proving environment. It is found that the translation between Specware and Isabelle is almost seamless and there is much potential in the use of Isabelle/HOL to discharge proof obligations that arise in developing Specware specifications, although the actual proving requires substantial knowledge and experience in logical calculus.Approved for public release; distribution is unlimited.Outstanding ThesisSingapore ST Electronics Ltd. author (civilian).http://archive.org/details/securitymodeling10945383
Diet and respiratory health/allergy in urban children : the PARIS (Pollution and Asthma Risk˸ an Infant Study) birth cohort
No full textIntroduction. Ces dernières décennies, la prévalence des pathologies allergiques a fortement augmenté. Elle est actuellement estimée à 25 % en France. Des facteurs de risque héréditaires, sociaux, environnementaux et comportementaux peuvent influencer la survenue des pathologies respiratoires et des allergies, et le rôle de l’alimentation est encore flou. Objectifs. Dans ce contexte et à partir des données du suivi de la cohorte de naissances PARIS, mes travaux de recherche en épidémiologie ont pour objectifs : (1) d’identifier et de caractériser des profils/groupes d’alimentation chez les nourrissons et chez les enfants à 8 ans ainsi que les trajectoires entre l’alimentation du nourrisson et celle de l’enfant ; (2) d’évaluer l’adhésion au régime méditerranéen (MD) à 8 ans et examiner les facteurs associés ; (3) d’étudier les associations entre ces profils alimentaires/groupes d’adhésion au régime MD et la santé respiratoire/les allergies chez les enfants à 8 ans. Matériel et méthodes. Le suivi des enfants de la cohorte de naissances PARIS (Pollution and Asthma Risk: an Infant Study) a permis d’identifier des profils d’alimentation du nourrisson grâce à une méthode de classification non-supervisée longitudinale et multidimensionnelle (kml3D) prenant en compte l’allaitement, le type de préparations infantiles données et la diversification alimentaire tout au long de la première année de vie des enfants. À 8 ans, l’alimentation de l’enfant a été évaluée à l’aide d’une méthode non supervisée (k-means) et grâce à deux scores d’adhésion au régime méditerranéen (MD). Les associations avec la santé respiratoire (exploration fonctionnelle respiratoire [VEMS, CVF], mesure de la fraction exhalée du monoxyde d’azote [FeNO]) et les allergies (diagnostics d’asthme, de rhinite et d’eczéma et sensibilisation allergénique) ont été étudiées à l’aide de modèles multivariés de régression linéaire et logistique en tenant compte des facteurs de confusion et d’interaction potentiels. Résultats. L’alimentation des nourrissons et des enfants de la cohorte PARIS est associée à la santé respiratoire et aux allergies à 8 ans. Cinq profils d’alimentation du nourrisson ont été identifiés. Comparés aux enfants caractérisés par la prise de préparations infantiles standards, les enfants du profil « allaitement » tendaient à avoir un risque plus faible d’asthme. De plus, les enfants du profil « préparations infantiles partiellement hydrolysées avec un label hypoallergénique » avaient une augmentation du risque d’être sensibilisés à au moins un allergène, d’avoir une FeNO >20 ppb (marqueur d’inflammation bronchique) et une diminution des paramètres de la fonction respiratoire (VEMS, CVF) à 8 ans. Une trajectoire d’alimentation a été identifiée, liant significativement le profil d’allaitement au groupe d’alimentation « plus saine » à l’âge scolaire. S’agissant de l’alimentation durant l’enfance, une alimentation « plus saine » ou « plus diversifiée » ou une forte adhésion au régime MD à 8 ans était bénéfique pour la santé respiratoire, l’asthme et la sensibilisation allergénique. Conclusion. Ces travaux contribuent à améliorer les connaissances sur les liens entre alimentation de l’enfant et santé respiratoire/allergies. Les résultats soutiennent les recommandations actuelles de santé publique privilégiant l’allaitement et une alimentation saine durant l’enfance, et apportent de nouvelles pistes pour prévenir les problèmes respiratoires et allergiques.Introduction. In recent decades, the prevalence of allergic diseases has increased, especially in industrialized countries. This prevalence is currently estimated at 25% in France. Genetic, social, environmental, and behavioral risk factors can influence the occurrence of respiratory diseases and allergies in children, and the role of diet is still unclear. Objectives. In this context and using data from the PARIS (Pollution and Asthma Risk: an Infant Study) birth cohort, my doctoral research in epidemiology aimed: (1) to identify and characterize infants’ feeding profiles and children’s dietary patterns at 8 years old, as well as the trajectories between infant and child feeding groups; (2) to assess and characterize the adherence to the Mediterranean diet (MD) at age 8 years; (3) to investigate the associations of infants’ feeding profiles/children’s dietary patterns/MD adherence groups with respiratory and allergic morbidity at 8 years of age. Material and methods. Infants with similar feeding practices over the first year of life were grouped using unsupervised multidimensional longitudinal cluster analysis (kml3D) considering: breastfeeding, type of infant formula consumed and solid food introduction. At 8 years of age, dietary patterns were assessed using an unsupervised method (k-means) and two MD adherence scores. Their associations with respiratory health (spirometry [FEV1, FVC], measurement of the fractional exhaled nitrogen oxide [FeNO]) and allergies (diagnoses of asthma, rhinitis and eczema and allergen sensitization) were studied using multivariable logistic and linear regression models adjusted for potential confounders. Results. PARIS children’s diet was associated with respiratory health and allergies at age 8 years. Five infants’ feeding profiles were identified. Compared to children characterized by standard infant formula consumption, children of the "breastfeeding" profile tended to have a lower risk of asthma at school age. In addition, children from the "partially hydrolyzed infant formula with a hypoallergenic label" profile had an increased risk of being sensitized, of having FeNO> 20 ppb (marker of bronchial inflammation) and lower respiratory function parameters (FEV1, FVC) at 8 years. One feeding trajectory was identified: children from the "breastfeeding" profile were more likely to belong to the "healthier" dietary pattern at school age. Regarding diet during childhood, a "healthier" or "more diverse" dietary pattern or high adherence to the MD at age 8 was found to be beneficial regarding respiratory health, asthma, and allergen sensitization. Conclusion. This work contributes to improving knowledge on the links between diet during infancy and respiratory health/allergies at school age. These results support current public health recommendations favoring breastfeeding and healthy eating during infancy
Isabelle/DOF: Design and Implementation
No full textThis is the author accepted manuscript. The final version is available from Springer Verlag via the DOI in this record17th International Conference, SEFM 2019
Oslo, Norway, September 18–20, 2019DOF is a novel framework for defining ontologies and enforcing them during document development and evolution. A major goal of DOF is the integrated development of formal certification documents (e. g., for Common Criteria or CENELEC 50128) that require consistency across both formal and informal arguments. To support a consistent development of formal and informal parts of a document, we provide Isabelle/DOF, an implementation of DOF on top of the formal methods framework Isabelle/HOL. A particular emphasis is put on a deep integration into Isabelleâs IDE, which allows for smooth ontology development as well as immediate ontological feedback during the editing of a document. In this paper, we give an in-depth presentation of the design concepts of DOFâs Ontology Definition Language (ODL) and key aspects of the technology of its implementation. Isabelle/DOF is the first ontology language supporting machine-checked links between the formal and informal parts in an LCF-style interactive theorem proving environment. Sufficiently annotated, large documents can easily be developed collabo- ratively, while ensuring their consistency, and the impact of changes (in the formal and the semi-formal content) is tracked automatically.IRT SystemX, Paris-Saclay, Franc
La construction d'un monde professionnel : entrées des jeunes praticiens dans la médecine générale
No full textIsabelle Baszanger
The young general practitioners in the medical field.
Using interviews with young medical doctors (general practitioners) the author studies the ways they organize their empirical practice (as opposed to theoretical knowledge) and constructs a typology which caracterizes specific modes of professionnal socialization. This leads the author to evaluate the social dimensions of the role of general practitioners.La socialisation professionnelle des étudiants en médecine implique la formation d'un univers conceptuel qui est une sorte de compromis entre le savoir médical et la pratique quotidienne. A partir d'entretiens avec de jeunes médecins généralistes l'auteur a étudié comment les jeunes médecins organisent leur pratique et construit une typologie reflétant ces mécanismes particuliers de socialisation.
Cette analyse conduit l'auteur à s'interroger sur la dimension sociale du rôle du médecin généraliste telle qu'il la perçoit.Baszanger Isabelle. La construction d'un monde professionnel : entrées des jeunes praticiens dans la médecine générale. In: Sociologie du travail, 25ᵉ année n°3, Juillet-septembre 1983. pp. 275-294
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