97,441 research outputs found

    Joshua Davis: Author of Spare Parts

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    Citation: K-State First (2016). Joshua Davis: Author of Spare Parts [Flier]. Manhattan, Kansas: K-State First.Flyer advertising Joshua Davis's author talk at Kansas State University

    Steven Johnson Author Talk Poster

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    K-State Book NetworkA poster advertising an author talk by Steven Johnson at Kansas State University on September 3, 2014. Steven Johnson's book "The Ghost Map" was the 2014-2015 common book

    Does a hospital admission in old age denote the beginning of life with a compromised health-related quality of life? A longitudinal study of men and women aged 65 years and above participating in the Stockholm Public Health Cohort

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    The objective of this study was to analyse how hospitalisation after the age of 60 affected individuals' health-related quality of life (HRQoL). The main hypothesis was that a hospital admission in old age can be seen as a proxy of ill health and possibly as a health divider, separating life into a healthy and an unhealthy part. The extent to which this is true depends on which disease individuals face and how functional ability and HRQoL are affected

    Intelligence and cardiovascular health : epidemiological studies of swedish men

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    Aim: A first aim of this thesis was to examine the relationship between intelligence in early adulthood and health outcomes, mainly cardiovascular morbidity and mortality, CVD, later in life using register-based data on Swedish men. A second aim was to increase understanding of the pathways between intelligence and CVD morbidity/mortality by studying the association between intelligence and smoking habits and nicotine dependence, who might act as mediators of the association between intelligence and mortality.Material and methods: The study populations in this thesis were created through record linkage of several national registers where IQ was collected from the Military Conscription Register. The analyses were based on all Swedish men born 1951 to 1984, depending on the paper, that went through conscription examinations. Also, for paper II parents of the men were analysed. Paper IV and V were based on Swedish male twins. The association between IQ and mortality was analyzed with Cox proportional hazards regression and conditional logistic regression models. The association between IQ and smoking status was analysed with linear, logistic and polytomous regression models and the association between IQ and nicotine dependence with quantitative genetic analyses.Results: In general, paper I-III support previous research about inverse associations between IQ and CVD morbidity/mortality. In addition to previous research our results revealed that IQ was associated with coronary heart disease, CHD, independently of socioeconomic position, SEP, (paper I) and that IQ was inversely and significantly associated with major subtypes of stroke (paper III). The strongest association found for hemorrhagic stroke. Further, the effect of IQ on mortality was found to be present also when offspring IQ was used as a proxy for parental IQ (paper II). In paper IV and V when the association of IQ and smoking and nicotine dependence was studied no evidence of a causal association was found. In paper IV smoking was associated with IQ but appeared to be the result of early environmental factors rather than resulting from a causal effect of intelligence. In paper V both IQ and nicotine dependence showed moderate heritability (0.58 and 0.39 respectively); however the phenotypic correlation was marginal (-0.08) and the overlap between genetic factors influencing IQ and nicotine dependence was small (-0.19).Conclusion: In this thesis, inverse associations between IQ score at the age of 18 and mortality later in life, mainly CVD, is presented. These associations were found within all socioeconomic strata, were robust to adjustment for indicators of SEP in childhood and adulthood and were present also when using offspring IQ as a proxy for parental IQ. Further, our results gave no support for IQ to be causally associated with smoking or that smoking or nicotine dependence act as important mediators of the IQ-CVD association. Finally, no evidence was provided for a common genetic factor behind IQ and nicotine dependence. This thesis provides information about the pathways of intelligence and mortality. However, more research is needed before any conclusions can be drawn with regard to public health policy.List of scientific papersI. Silventoinen, K, Modig Wennerstad, K, Tynelius, P, Rasmussen, F. (2007). "Association between intelligence and coronary heart disease mortality: a population-based cohort study of 682,361 Swedish men" European Journal of Cardiovasc Prevention and Rehabilitation 14(4): 555-60. https://doi.org/10.1097/HJR.0b013e328014672e II. Modig Wennerstad, K, Silventoinen, K, Batty, G.D, Tynelius, P, Bergman, L, Rasmussen, F. (2008). "Association between offspring intelligence and parental mortality: a population-based cohort study of one million Swedish men and their parents." Journal of Epidemiol Community Health 62(8): 722-7. https://doi.org/10.1136/jech.2007.065623 III. Modig Wennerstad, K, Silventoinen, K, Tynelius, P, Bergman, L, Rasmussen, F. (2009). "Association between intelligence and type specific stroke: a population-based cohort study of early fatal and non-fatal stroke in one million Swedish men". Journal of Epidemiol Community Health. https://pubmed.ncbi.nlm.nih.gov/19833609 IV. Modig Wennerstad, K, Silventoinen, K, Tynelius, P, Bergman, L, Kaprio, J, Rasmussen, F. (2010). "Associations between IQ and cigarette smoking among Swedish male twins". Social Science & Medicine 70(4): 575-581. https://doi.org/10.1016/j.socscimed.2009.10.050 V. Modig Wennerstad, K, Silventoinen, K, Tynelius, P, Kaprio, J, Rasmussen, F. (1970). "Genetics of the association between intelligence and nicotine dependence: a study of Swedish male twins". [Submitted]</p

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Expanding “Communities and Collections” in the K-State Research Exchange (K-REx) to benefit the K-State Community and Beyond

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    Kansas State University has used its institutional repository, the K-State Research Exchange (K-REx), to store and share its first year experience program, K-State First, and notably its common reading program, K-State First Book. We have done so with the aim that the accessibility and preservation of these documents ensures program stability, promotes engagement with first year programming, and provides the ability to foster growth,educational opportunities, and community building outside of K-State. Moving away from research concentrated repositories and taking a more holistic approach to scholarship, especially when realizing the pedagogical significance of collaborative campus programming, institutions can showcase, discover, preserve, and grow programs that shape campus communities and engagement. This session will provide an overview of K-REx and spotlight the digital archive of the university’s first year experience program and common reading program, K-State First Book. We will discuss the benefits and challenges to expanding the purview of your repositories. We talkthrough the types of materials we decide to host in our repository and why we share what we do. We will also provide recommendations on new ways to evaluate what belongs in institutional repositories and how this diversity can benefit your program, your institution, the community, and others

    Ready Player One Program Event Poster

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    K-State Book NetworkA poster advertising an author talk by Ernest Cline at Kansas State University on October 10, 2013. Ernest Cline's book "Ready Player One" was selected as the 2013-2014 common book

    Depolarization and decreased surface expression of K+ channels contribute to NSAID-inhibition of intestinal restitution

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    Non-steroidal anti-inflammatory drugs (NSAIDs) contribute to gastrointestinal ulcer formation by inhibiting epithelial cell migration and mucosal restitution; however, the drug-affected signaling pathways are poorly defined. We investigated whether NSAID inhibition of intestinal epithelial migration is associated with depletion of intracellular polyamines, depolarization of membrane potential (Em) and altered surface expression of K+ channels. Epithelial cell migration in response to the wounding of confluent IEC-6 and IEC-Cdx2 monolayers was reduced by indomethacin (100μM), phenylbutazone (100μM) and NS-398 (100μM) but not by SC-560 (1μM). NSAID-inhibition of intestinal cell migration was not associated with depletion of intracellular polyamines. Treatment of IEC-6 and IEC-Cdx2 cells with indomethacin, phenylbutazone and NS-398 induced significant depolarization of Em, whereas treatment with SC-560 had no effect on Em. The Em of IEC-Cdx2 cells was: −38.5±1.8mV under control conditions; −35.9±1.6mV after treatment with SC-560; −18.8±1.2mV after treatment with indomethacin; and −23.7±1.4mV after treatment with NS-398. Whereas SC-560 had no significant effects on the total cellular expression of Kv1.4 channel protein, indomethacin and NS-398 decreased not only the total cellular expression of Kv1.4, but also the cell surface expression of both Kv1.4 and Kv1.6 channel subunits in IEC-Cdx2. Both Kv1.4 and Kv1.6 channel proteins were immunoprecipitated by Kv1.4 antibody from IEC-Cdx2 lysates, indicating that these subunits co-assemble to form heteromeric Kv channels. These results suggest that NSAID inhibition of epithelial cell migration is independent of polyamine-depletion, and is associated with depolarization of Em and decreased surface expression of heteromeric Kv1 channels.ID: S0006295207001931; M3: Article; Accession Number: S0006295207001931; Author: L.C. Freeman (b); Author: D.F. Narvaez (a); Author: A. McCoy (a); Author: F.B. von Stein (c); Author: S. Young (b); Author: K. Silver (a); Author: S. Ganta (b); Author: D. Koch (b); Author: R. Hunter (b); Author: R.F. Gilmour (c); Author: J.D. Lillich (a, ⁎); Affiliation: Department of Clinical Sciences, Kansas State University, Manhattan, KS 66506, United States; Affiliation: Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, United States; Affiliation: Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, United States; Keyword: Non-steroidal anti-inflammatory drugs; Keyword: Intestinal epithelial cells; Keyword: Membrane potential; Keyword: Potassium channels; Number of Pages: 12; Language: English;Source type: Electronic(1)http://search.ebscohost.com/login.aspx?direct=true&db=edselp&AN=S0006295207001931&site=eds-live&scope=sit

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
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