27 research outputs found
Effect of multiple 1-MCP treatments to extend shelf life of tomato
No full textEthylene is a plant growth hormone responsible for ripening and senescence of fresh produce. But production of excess ethylene leads to over ripening and facilitates microbial growth thereby reducing the shelf life. Therefore control over ethylene action is required. To increase shelf life of fresh produce 1-Methylenecyclopropene (1-MCP) ethylene antagonist shown promising result by inhibiting ethylene response at receptor level. The current 1-MCP treatment requires a storage room with controlled atmosphere overnight. However this treatment is effective only for the initial period of time as continuous formation of ethylene receptors triggers ripening. Controlled Release Packaging (CRP) technology can be used as an alternative to existing 1-MCP treatment by providing the ability to replenish 1-MCP and prolong is exposure to fresh fruits. The first objective of this study was to evaluate the effect of multiple 1-MCP treatments on quality attributes of fresh tomatoes. This study was conducted at turning stage of tomatoes using three treatments: 1) control (no 1-MCP), 2) single 1-MCP treatment (1200nl) and 3) multiple 1-MCP treatments (100nl/day for 12 days). The multiple 1-MCP treatments prolonged the shelf life of tomatoes by maintaining quality attributes including weight, color, firmness, pH and total soluble solids (TSS) at room temperature compared to the single 1-MCP treatment. Not all quality attributes were affected to the same extent, the strongest effect of multiple 1-MCP treatments was on firmness of the tomatoes and not much difference was noted on TSS and pH of tomato juice. The second objective was to quantify the release of 1-MCP through Tyvek, LDPE and PLA polymer sachets at room temperature under 90% RH to test their potential usage as CRP film material. The release of 1-MCP through Tyvek sachet is almost 90% in 10-12 hours whereas LDPE sachet has a slower a release around 10% in 10-12 hours. Both polymers have potential use as an active layer in CRP system. PLA sachet does not release 1-MCP, but it may be used as a barrier layer of the package of CRP system.M.S.Includes bibliographical referencesby Tulsi Pate
Influence of tulsi Ocimum sanctum extract on fish health: Growth, hematology, serum immune parameters, and antioxidant status in Common Carp
No full textObjective
In aquaculture, the trend is shifting towards using plant-derived alternatives that are abundant in phytochemicals as effective replacements for traditional antibiotics and synthetic feed additives. In the present study, the effects of tulsi Ocimum sanctum extract on growth performance, hemato-biochemical indices, serum immune parameters, and antioxidant parameters in Common Carp Cyprinus carpio were investigated.
Methods
Common Carp (mean body weight ± SD = 10.6 ± 0.13 g) were fed experimental diets that contained tulsi leaf extract at 0.0 (control), 0.5, 1.0, and 1.5% for 60 d (25 fish/treatment).
Results
The findings revealed a considerable enhancement in growth performance and a decreased feed conversion ratio, especially for the 1.0% tulsi-based diet. Additionally, weight gain and feed conversion ratio exhibited significance at both the linear and quadratic levels, as indicated by polynomial contrasts. The hematological and biochemical profiles exhibited improvements in groups receiving tulsi-enriched diets. The antioxidant status of fish serum exhibited a notable increase, as evidenced by elevated activities of total antioxidant capacity, superoxide dismutase, and catalase in fish that received the 1.0% and 1.5% tulsi-based diets. Tulsi-supplemented diets led to remarkable enhancements in serum lysozyme activity, alternative complement activity, and total immunoglobulin content. Moreover, tulsi supplementation at 1.0% and 1.5% showcased a significant reduction in serum glucose and cortisol levels compared to the other groups.
Conclusions
In conclusion, tulsi extract emerged as a valuable asset, positively influencing growth, blood parameters, antioxidant balance, and serum immune response in Common Carp, particularly at supplementation levels ranging from 1.0% to 1.5% in the diet.King Saud University, Riyadh, Saudi Arabia [RSPD2025R758]We extend our appreciation to the Researchers Supporting Project (RSPD2025R758), King Saud University, Riyadh, Saudi Arabia. Author contributions are as follows: S. S. Habib, S. Naz, and M. Zahid conceptualized and designed the study; S. S. Habib, M. Ullah, and S. Naz contributed writing and preparation of the original draft; S. Naz and K. Khan performed the sampling; S. Majeed and UE. Acar analyzed the data; and K. H. Rind, M. Mohany, F. Fazio, UE. Acar, and C. Cravana reviewed and edited the manuscript. All authors read and agreed to the published version of the manuscript
Understanding the Molecular Level Interactions of Cancer Inhibitor Imatinib with Human Fibroblast Growth Factor-1
No full textFibroblast growth factors (FGFs) lack signal sequences, and are exported through endoplasmic reticulum (ER)-Golgi-independent non-classical routes. FGFs work as modulators of various cellular activities like mitosis, differentiation, survival etc. Among the FGF family, which comprises of 23 different heparin proteins, human FGF-1 (hFGF-1), a potent angiogenic factors are one of the targets in cancer inhibition, as they are involved in blood vessel formation in tissues. There has been intensive research directed at the development of drugs that could effectively inhibit angiogenesis. In this context, the purpose of this study is to fully understand the molecular principles essential to determine probability of inhibition of hFGF-1 signaling transduction by imatinib. Imatinib, a 2-phenyl amino pyrimidine derivative is a tyrosine kinase inhibitor with antineoplastic activity. Imatinib binds to the intracellular pocket located within tyrosine kinases and inhibit the downstream cell proliferation events, but the exact molecular mechanism is still elusive. In this study, expression of hFGF-1 in recombinant E. coli was carried out, and the expressed protein was purified using heparin affinity column chromatography. The structural interactions governing imatinib-hFGF-1 interaction was studied by monitoring its stability, conformation and binding affinity by equilibrium unfolding using steady state fluorescence and proteolytic digestion assay. These data show that imatinib binds to hFGF-1 and enhances its thermal stability and solvent accessibility. In addition, biacore analysis was carried out to determine the binding affinity of imatinib to hFGF-1
Effect of Antimicrobial Agents on Modification of Coir
No full textAbstractCoir yarns were coated with three natural anti-microbial agents - Cashew Nut Shell Liquid (CNSL), neem oil and tulsi oil for improving its hydrophobicity, tensile strength and biological resistance. Microbial degradation study was performed with A. niger as test organism. The results indicated that coating of coir yarns was capable of increasing tensile strength by 17% and reducing moisture absorption by 34%. Microbial activity of CNSL coated coir yarns was reduced to 95%. Coating with neem oil was found to be less effective while coating with tulsi oil adversely affected the physical and engineering properties of coir
Author response: Coordinated control of terminal differentiation and restriction of cellular plasticity
No full textCorrection: Alzheimer’s disease polygenic risk score as a predictor of conversion from mild-cognitive impairment
No full textIn the original Article, Professor Alan Thomas was not acknowledged as an author. This has been updated in both the HTML and PDF versions of this Article.</p
Understanding the Function of a Pro-Angiogenic Polypeptide hFGF-1 with a Cancer Inhibitor Imatinib
No full text
DESIGNER HERBAL FOODS-NEW HOPE TO IMPROVE HUMAN HEALTH
No full textDesigner foods are conventional foods which have been fortified with ingredients which fight against deadly diseases. Now-a-days people eating habit and lifestyle is changing, they are consuming junk food which is increasing the chance of various diseases. Herbs are been used since time immemorial as medicines. Herbs have active ingredients which have the property to fight against diseases. In pharmaceutical companies they only add the active ingredient in the drug but in designer foods whole herb extract is added which gives added benefit. Designer food containing the whole herb will be more beneficial than drug containing only the active ingredient. Market available drugs have various side effects but these designer herbal foods will not cause any side effects. Though these designer herbal food will take time to cure the disease. Herbs like Tulsi, Amla, Ashwagandha, Aloe vera & Shankhpushpi has been discussed in this review article, there health benefits and food products in which they can be fortified.
KEYWORDS: Designer foods; Fortification; Herbs; Health benefits
