101,980 research outputs found
Data set fromMazzaccaro D, Miri R, Derbel B, Modafferi A, Nano G. Hypogastric artery coverage during endovascular aneurysm repair in octogenarian and younger patients. J Cardiovasc Med (Hagerstown). 2019 Aug;20(8):557-563. doi: 10.2459/JCM.0000000000000799. PMID: 30950984.
No full textData set fromMazzaccaro D, Miri R, Derbel B, Modafferi A, Nano G. Hypogastric artery coverage during endovascular aneurysm repair in octogenarian and younger patients. J Cardiovasc Med (Hagerstown). 2019 Aug;20(8):557-563. doi: 10.2459/JCM.0000000000000799. PMID: 30950984.
This is the abstract:
Aim: To report our experience about hypogastric artery coverage during endovascular aneurysm repair (EVAR) for aortoiliac aneurysms in patients younger than 80 years (group A) compared with octogenarian patients (group B).
Methods: Data of consecutive EVAR with hypogastric artery coverage from 01/1998 to 12/2016 were retrospectively analyzed. Primary outcomes were the occurrence of ischemic colitis, type II endoleak and buttock claudication both at 30 days and in the long term. P values less than 0.05 were considered statistically significant.
Results: The hypogastric artery was covered in 107 patients. Twenty-three (21.5%) were octogenarian (group B). At 30 days, one type II endoleak occurred in group B, whereas 16 patients of group A experienced buttock claudication. There were no cases of ischemic colitis. During follow-up (median 63.5 months), no cases of ischemic colitis occurred. Six new type II endoleaks were recorded (five in group B and one in group A, P = 0.0001). Buttock claudication persisted in four patients of group A. No new cases of buttock claudication were observed.
Conclusion: Unilateral hypogastric artery coverage during EVAR for aortoiliac aneurysms can be performed with an acceptable rate of postoperative complication. Postoperative buttock claudication was more frequent in younger patients, whereas a type II endoleak occurred mostly in octogenarian patients during follow-up
Ecological costs of botanical nano-insecticides
No full textBotanical nano-insecticides are a trend in pest control. The natural origin of the active substances, alongside with the methodological approach granted by nanotechnologies are a promising combination of innovation and eco-sustainability, hot topics in the context of ecological transition in agriculture. Nevertheless, their field application is still limited, due to production challenges and risk assessment concerns. Nanoformulations have some advantages over traditional bioinsecticides, including increased bioactivity and persistence, and slow-release rates. Recent research reported promising insecticidal activity of nano-emulsions, micro-emulsions, and nanoparticles loaded with different botanical extracts, oils, and essential oils. Though, despite their proven efficacy against insect pests and vectors, a limited number of studies investigated their safety towards nontarget organisms and fate in the environment. This mini-review provides an overview of the side-effects of botanical nano-insecticides and the main challenges to improve their sustainability in term of ecological and production cost
Assessment of long-term survival and stroke after carotid endarterectomy and carotid stenting in patients older than 80 years
No full textOBJECTIVE:
The objective of this study was to analyze preoperative risk factors affecting long-term survival and the occurrence of stroke in patients older than 80 years undergoing either carotid endarterectomy (CEA) or carotid artery stenting (CAS) for carotid stenosis.
METHODS:
Data of all consecutive patients treated from January 1999 to December 2017 were retrospectively reviewed and outcomes analyzed. Kaplan-Meier analysis was used to estimate long-term survival and the risk of stroke for both groups. Cox proportional hazards analysis was used to assess the relative risk of all-cause mortality and long-term stroke for patients in the presence of selected comorbidities, including preoperative symptoms, coronary artery disease, chronic renal failure, atrial fibrillation (AF), hypertension, diabetes mellitus, and dyslipidemia. A P value <.05 was considered statistically significant.
RESULTS:
A total of 473 patients older than 80 years (298 men [63%]) underwent either CEA (n = 178) or CAS. At 30 days, one patient died in the CEA group of unrelated causes; no deaths were recorded after CAS (0.6% vs 0%; P = .18). At 5 years, survival was 67.6% ± 4.9% after CEA and 90.2% ± 2.3% after CAS (P < .0001). The main cause of death after CEA and CAS was a neoplasm. Estimated freedom from any stroke at 5 years was 97.3% ± 0.5% after CEA and 93.2% ± 1.2% after CAS (P = .07). The presence of preoperative AF significantly affected long-term mortality after CAS (hazard ratio [HR], 1.56; 95% confidence interval [CI], 1.34-1.98; P = .04) as well as being classified as American Society of Anesthesiologists class 3 at evaluation of the preoperative anesthesiology risk. The presence of preoperative AF was the only factor that significantly affected the occurrence of long-term stroke after both CAS (HR, 2.28; 95% CI, 1.86-5.63; P = .001) and CEA (HR, 3.45; 95% CI, 2.29-8.19; P = .005).
CONCLUSIONS:
Both CEA and CAS showed low 30-day mortality and any-stroke rates in patients older than 80 years. In the long term, survival was significantly better after CAS; however, deaths after CEA and CAS were mainly unrelated to the procedure. No significant differences were recorded in the occurrence of any stroke in the long term. The presence of preoperative AF significantly affected long-term survival after CAS as well as being classified as American Society of Anesthesiologists class 3 at evaluation of the preoperative anesthesiology risk. The presence of preoperative AF also significantly affected long-term risk of stroke after both CAS and CEA
Data set from Mazzaccaro D, Modafferi A, Malacrida G, Nano G. Assessment of long-term survival and stroke after carotid endarterectomy and carotid stenting in patients older than 80 years. J Vasc Surg. 2019 Aug;70(2):522-529. doi: 10.1016/j.jvs.2018.10.121. Epub 2019 Mar 2. PMID: 30837178.
No full textData set from Mazzaccaro D, Modafferi A, Malacrida G, Nano G. Assessment of long-term survival and stroke after carotid endarterectomy and carotid stenting in patients older than 80 years. J Vasc Surg. 2019 Aug;70(2):522-529. doi: 10.1016/j.jvs.2018.10.121. Epub 2019 Mar 2. PMID: 30837178.
This is the abstract:
Objective: The objective of this study was to analyze preoperative risk factors affecting long-term survival and the occurrence of stroke in patients older than 80 years undergoing either carotid endarterectomy (CEA) or carotid artery stenting (CAS) for carotid stenosis.
Methods: Data of all consecutive patients treated from January 1999 to December 2017 were retrospectively reviewed and outcomes analyzed. Kaplan-Meier analysis was used to estimate long-term survival and the risk of stroke for both groups. Cox proportional hazards analysis was used to assess the relative risk of all-cause mortality and long-term stroke for patients in the presence of selected comorbidities, including preoperative symptoms, coronary artery disease, chronic renal failure, atrial fibrillation (AF), hypertension, diabetes mellitus, and dyslipidemia. A P value <.05 was considered statistically significant.
Results: A total of 473 patients older than 80 years (298 men [63%]) underwent either CEA (n = 178) or CAS. At 30 days, one patient died in the CEA group of unrelated causes; no deaths were recorded after CAS (0.6% vs 0%; P = .18). At 5 years, survival was 67.6% ± 4.9% after CEA and 90.2% ± 2.3% after CAS (P < .0001). The main cause of death after CEA and CAS was a neoplasm. Estimated freedom from any stroke at 5 years was 97.3% ± 0.5% after CEA and 93.2% ± 1.2% after CAS (P = .07). The presence of preoperative AF significantly affected long-term mortality after CAS (hazard ratio [HR], 1.56; 95% confidence interval [CI], 1.34-1.98; P = .04) as well as being classified as American Society of Anesthesiologists class 3 at evaluation of the preoperative anesthesiology risk. The presence of preoperative AF was the only factor that significantly affected the occurrence of long-term stroke after both CAS (HR, 2.28; 95% CI, 1.86-5.63; P = .001) and CEA (HR, 3.45; 95% CI, 2.29-8.19; P = .005).
Conclusions: Both CEA and CAS showed low 30-day mortality and any-stroke rates in patients older than 80 years. In the long term, survival was significantly better after CAS; however, deaths after CEA and CAS were mainly unrelated to the procedure. No significant differences were recorded in the occurrence of any stroke in the long term. The presence of preoperative AF significantly affected long-term survival after CAS as well as being classified as American Society of Anesthesiologists class 3 at evaluation of the preoperative anesthesiology risk. The presence of preoperative AF also significantly affected long-term risk of stroke after both CAS and CEA
UTILITA' DEL DOSAGGIO SERICO DELLA PROTEINA ACIDA IMMUNOSOPPRESSIVA E DEL CA125 IN PAZIENTI CON CARCINOMA DELL'OVAIO.
No full textThe reversed bell-bottom technique (ReBel-B) for the endovascular treatment of iliac artery aneurysms
No full textObjective: To describe the results of the reversed bell-bottom (ReBel-B) technique for the endovascular treatment of iliac aneurysms (IA) involving the origin of hypogastric artery (HA). Methods: The ReBel-B technique is a strategy for the occlusion of HA in selected patients presenting with IA, in whom the HA cannot be spared or safely occluded with coils or vascular plugs. When employing this technique, an iliac flared (“bell-bottom”) extension is deployed in a reverse fashion, through a contralateral crossover femoral access that allows the occlusion of the HA at its origin, by exploiting the flared “bell” part of the reversed endograft. A second limb is then deployed to complete the implant, from the common iliac to the external iliac artery, inside the previous graft. Data of all consecutive patients treated with this technique in our experience were then retrospectively reviewed, and outcomes analyzed. Results: The ReBel-B technique was employed in total of six patients who came in an emergent setting for the rupture of a common IA, from January 2014 to December 2018. Endovascular exclusion was performed using a ReBel-B graft plus iliac leg in five out of six cases. In the remaining case, a bifurcated aortic endograft was used to complete the aneurysm exclusion. Technical success was 100%. No complications occurred. Conclusions: In selected cases, the ReBel-B technique can be used for the complete exclusion of IA preventing type II endoleak from the HA, when the embolization with coils or plug or the preservation of the HA is anatomically unfeasible
Hypogastric artery coverage during endovascular aneurysm repair in octogenarian and younger patients
No full textAim
To report our experience about hypogastric artery coverage during endovascular aneurysm repair (EVAR) for aortoiliac aneurysms in patients younger than 80 years (group A) compared with octogenarian patients (group B).
Methods
Data of consecutive EVAR with hypogastric artery coverage from 01/1998 to 12/2016 were retrospectively analyzed. Primary outcomes were the occurrence of ischemic colitis, type II endoleak and buttock claudication both at 30 days and in the long term. P values less than 0.05 were considered statistically significant.
Results
The hypogastric artery was covered in 107 patients. Twenty-three (21.5%) were octogenarian (group B). At 30 days, one type II endoleak occurred in group B, whereas 16 patients of group A experienced buttock claudication. There were no cases of ischemic colitis. During follow-up (median 63.5 months), no cases of ischemic colitis occurred. Six new type II endoleaks were recorded (five in group B and one in group A, P U 0.0001). Buttock claudication persisted in four patients of group A. No new cases of buttock claudication were observed.
Conclusion
Unilateral hypogastric artery coverage
during EVAR for aortoiliac aneurysms can be performed
with an acceptable rate of postoperative complication.
Postoperative buttock claudication was more frequent in
younger patients, whereas a type II endoleak occurred
mostly in octogenarian patients during follow-up
Human face-off: a new method for mapping evolutionary rates on three-dimensional digital models
No full textReal-time crisis mapping of natural disasters using social media
No full textThe proposed social media crisis mapping platform for natural disasters uses locations from gazetteer, street map, and volunteered geographic information (VGI) sources for areas at risk of disaster and matches them to geoparsed real-time tweet data streams. The authors use statistical analysis to generate real-time crisis maps. Geoparsing results are benchmarked against existing published work and evaluated across multilingual datasets. Two case studies compare five-day tweet crisis maps to official post-event impact assessment from the US National Geospatial Agency (NGA), compiled from verified satellite and aerial imagery sources
Endovascular aortic repair with aneurysm sealing system and parallel grafts: is it the solution for type I endoleaks and target vessels’ thrombosis?
No full textBACKGROUND Type I endoleaks (EL) from “gutters” and stent-graft compression represent the two main issues of the endovascular aortic repair (EVAR) using the chimney/snorkel technique. The potential impact of these complications would probably be reduced in presence of a sealing polymer, which could fill the “gutters” and can conform more precisely around the grafts without any adjunctive radial force.
Aim of the study was to assess the reported rate of type I EL and target vessels’ thrombosis occurring after chimney/snorkel EVAR using traditional endografts (Ch-EVAR) and those reported after EVAR with chimney using an Endovascular Aneurysm Sealing system (Ch-EVAS).
METHODS Analysis of the literature on Pubmed and Medline with the terms “Chimney” and “Parallel grafts” was performed. Case series of either Ch-EVAR or Ch-EVAS of juxtarenal/pararenal aneurysms, pseudoaneurysms and type Ia EL following EVAR were considered. Only papers with full text available in English and reporting complete data about the occurrence of endoleaks and stent-graft thrombosis with at least 1 month of follow-up were included in the analysis.
Exclusion criteria were papers with incomplete data, inadequate follow-up or reporting less than 5 cases. For both Ch-EVAR and Ch-EVAS, the total proportion of type I EL and target vessels’ thrombosis occurring during the follow-up was calculated, along with the respective 95% confidence intervals (CI). The R program (http://CRAR.R-project.org) with “Metaprop” package was used.
RESULTS The search on Pubmed retrieved 173 papers. Of these, only 24 papers were included in the analysis (20 in the Ch-EVAR group and 4 in the Ch-EVAS group). Data about 563 Ch-EVAR and 61 Ch-EVAS performed from January 2008 to December 2016 were analyzed. During the follow-up, a type I EL occurred in 10% of patients submitted to Ch-EVAR (95% CI: 8%-13%) and in 8% of patients submitted to Ch-EVAS (95% CI: 4%-19%). Target vessels thrombosis occurred in 9% of cases after Ch-EVAR (95% CI: 7%-12%) and in 6% of cases after Ch-EVAS (95% CI: 2%-17%). The nature of the reported studies did not allow the assessment of any statistically significant difference between the outcomes of both techniques.
CONCLUSIONS The reported rate of type I EL and target vessels’ thrombosis occurring after Ch-EVAR tended to be slightly higher than those reported after Ch-EVAS, however it was not possible to assess if these data differed significantly. A randomized controlled trial comparing the outcomes of Ch-EVAR and Ch-EVAS is then needed to improve the knowledge about this topic
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