387 research outputs found
Soseki Natsume and Sojin Fujishiro ― About Wagahai wa Neko de Aru ―
No full textP(論文)This paper examines an article by Sojin Fujishiro, The Heated Record of a Cat Writer, and I Am a Cat by Soseki Natsume. The Cat Writer says that Natsume’s cat is borrowed from Germany. The author of the Cat Writer is Teisuke Fujishiro, who revealed the hidden name of Murr the tomcat, popular in the German literary world.
Fujishiro and Natsume were friends. Through national scholarships, one studied in the U.K, the other in Germany.
In addition, it is said that Natsume’s cat does not clarify the name of the German cat. This article covers both I Am a Cat, and how Natsume answers the attack of the Cat Writer.departmental bulletin pape
Role of antisecretory agents for gastric endoscopic submucosal dissection
No full textGastric endoscopic submucosal dissection (ESD) causes artificial gastric ulcers and there is no consensus regarding the optimal perioperative management in terms of prevention of intra- or postoperative bleeding and promotion of healing. Traditionally, 8-week administration of proton pump inhibitors (PPI) and mucosal protective agents were used in the same way as for peptic ulcer management. However, recent studies have revealed that prior use of PPI might reduce intraoperative bleeding or early-phase postoperative bleeding, and combination of histamine-2 receptor antagonist (H2RA), and second-look endoscopy might have a similar effect on postoperative bleeding to PPI. Additionally, the advantage of PPI over H2RA is not proven and the optimal duration of PPI may be shortened until 2 weeks when the deteriorating factors for ESD ulcer are excluded. Furthermore, mucosal protective agents may facilitate ulcer healing. Further studies are needed to determine the optimal treatment protocol before and after ESD for both prevention of bleeding complication and promotion of ulcer healing, by using available antisecretory agents and mucosal protective agents
Advanced Diagnostic and Therapeutic Endoscopy for Early Gastric Cancer
No full textEndoscopy is mandatory to detect early gastric cancer (EGC). When considering the cost-effectiveness of the endoscopic screening of EGC, risk stratification by combining serum pepsinogen values and anti-H. pylori IgG antibody values is very promising. After the detection of suspicious lesions of EGC, a detailed observation using magnifying endoscopy with band-limited light is necessary, which reveals an irregular microsurface and/or an irregular microvascular pattern with demarcation lines in the case of cancerous lesions. Endocytoscopy enables us to make an in vivo histological diagnosis. In terms of the indications for endoscopic resection, the likelihood of lymph node metastasis and technical difficulties in en bloc resection is considered, and they are divided into absolute, expanded, and relative indications. Endoscopic mucosal resection and endoscopic submucosal dissection are the main treatment modalities nowadays. After endoscopic resection, curability is evaluated histologically as endoscopic curability (eCura) A, B, and C (C-1 and C-2). Recent evidence suggests that the outcomes of endoscopic resection for many EGCs are comparable to those of gastrectomy and that endoscopic resection is the gold standard for node-negative early gastric cancers. Personalized medicine is also being developed to overcome the unmet needs in treatments of EGC, for example the further expansion of indications and newer resection techniques, such as full-thickness resection
Current Perspective on Endocytoscopic Diagnosis in the Esophagus Based on the Multicenter Study at the Endoscopic Forum Japan
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