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Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Cytogenetic pattern in leukemic cells of patients with constitutional chromosome anomalies
No full textChromosome pattern, occupation and clinical features in patiens with acute non-lymphocytic leukemia.
No full textChromosome banding pattern of bone marrow cells, cell morphology according to the FAB classification, and clinical finding were compared in two groups of adult patients with acute nonlymphocytic leukemia (ANLL): 52 patients occupationally exposed to chemical solvents, insecticides, or petrol products, and 110 patients with no history of occupational exposure to potential mutagenic/carcinogenic agents. Striking differences were found between the two groups: (1) Clonal chromosomal aberrations were present in 75% of exposed patients compared with only 32% in the nonexposed group. (2) Of the patients exposed to solvents and insecticides 92% had abnormal chromosomes, whereas only 29% of patients exposed to petrol products showed abnormalities; in the total material 10/13 exposed patients with normal chromosomes were exposed to petrol products. (3) The relationship between chromosomal abnormality and exposure was evident in both females and males. However, only 29% of women with an abnormal karyotype were exposed, whereas 70% of males with an abnormal karyotype were exposed. (4) The incidence of certain characteristic karyotypic abnormalities, i.e., -5/5q-, 7/7q-, +8, +21, t(8;21), and t(9;22), were decidedly more common in exposed than in nonexposed patients. At least one of these changes were present in 92% of exposed patients with aberrations, whereas in the nonexposed group the incidence was only 60%. (5) The monocytic varieties of ANLL (M4 + M5) were more common in the nonexposed patients, whereas erythroleukemia (M6) was more common in the exposed group. The predominance of abnormal karyotypes in the exposed compared to the nonexposed patients was similar in leukemia types M1 + M2 and in M4 + M5. (6) There was no difference in survival time between the two groups and the same correlation was obvious in both exposed and nonexposed patients: patients who had only abnormal metaphases had poorer prognosis than those with normal bone marrow metaphases only (6 vs 1.5 months). This correlation was obvious in patients classified as acute myeloid leukemia (AML) as well as in the monocytic varieties of ANLL
Chromosomal, morphological and clinical correlations in blastic crisis of chronic myeloid leukemia. A study of 69 cases.
No full textThe karyotypic pattern in 69 patients with Ph1-positive chronic myeloid leukaemia (CML) was investigated during the blastic phase (BC) and correlated with survival and certain parameters of potential prognostic significance, including blast morphology, basophilia and thrombocytopenia. There was no difference in median survival in BC between patients with and without aberrations in addition to the Ph1. Nor were there any differences in this respect among patients with the specific aberrations +Ph1, +8, iso(17q), or other abnormalities. There was no correlation between the incidence of thrombocytopenia and any particular karyotypic change. However, the incidence of basophilia was a characteristic feature for patients with an iso(17q). The survival time in BC was considerably longer in patients with a lymphoid morphology of the blastic cells compared to the myeloid varieties, and within the myeloid varieties the survival in BC was longer in patients with granular differentiated blasts than in those with granular atypical blast cells. No obvious correlation was apparent between blast morphology and karyotypic pattern. However, a pattern was discernible regarding survival and certain chromosomal changes within some morphologic groups: in patients with granular differentiated and lymphoid morphology, the median survival in BC was considerably longer when the bone marrow cells had a Ph1 as the sle abnormality compared to patients who had additional aberrations
A collaborative study of the relationship of the morphological type of acute non-lymphocytic leukemia with patients'age and karyotype.
No full textconsecutive patients with nonlymphocytic leukemia from
six independent laboratories in the United States. Europe.
and Australia were combined. The karyotypic pattern
determined with banding was correlated with the patient’s
age and the morphological type of leukemia according to
the FAB classification. Of the 503 patients in the combined
study. 260 had acute myeloblastic leukemia (AML. Ml and
M2). 142 had acute myelomonocytic leukemia (AMMoL,
M4). 43 had acute monocytic leukemia (AMoL. M5). 30 had
erythroleukemia (EL. M6). and 28 had acute promyelocytic
leukemia (API. M3). The percentage of patients with an
abnormal karyotype was higher in EL (63%) and AMI (59%)
than in AMMoL (40%) and AMoL (42%). In AML, the
chromosome pattern showed a clear correlation with age.
The consistent translocation involving nos. 8 and 21 . which
is specifically associated with AML M2. occurred with the
greatest frequency in younger patients. particularly those
under the age of 45 yr. Other abnormalities. notably loss of
no. 5 or part of its long arm. were not seen in children and
showed a progressive increase in frequency with increasing
age. Still other abnormalities. such as - 7 or + 8. were
present in all age groups. but were more common in older
than in younger groups. In AMMoL. on the other hand. loss
of no. 5 was rare. loss of no. 7 was less frequent in older
than in younger patients. and gain of no. 8 showed some
increase with age. Young patients with AMoL had either a+ 8 or a translocation involving the long arm of no. 11
(1 1 q23); older patients also had +8 or various other
changes. with loss of no. 7 rare and loss of no. 5 not
observed in any patient. In EL. the percentage of aneuploid
patients was highest particularly in older patients. of whom
75% had an abnormal karyotype. Although loss of no. 5 or
no. 7 was not seen in any patient under age 50. loss of one
or both was seen in 47% of all EL patients over age 50. On
the other hand. a + 8 was almost twice as common in
younger than in older patients. In APL. 39% had the
t(1 5;1 7) that is specifically associated with this type of
leukemia; other abnormalities were seen in a few older
patients. In summary. loss of no. 5 and/or no. 7 occurred in
30% of all EL patients. in 1 9% of all AMI patients. and in
only 7% of AMMoL. in 5% of AMoL. and in 4% of APL
patients. These observations are significant because
patients with ANIL secondary to aggressive therapy for a
primary malignant disease tend to have AML or EL. and the
majority have - 5 and/or - 7. These same morphological
types of leukemia and the same abnormalities. - 5 and I or
- 7. are also increased in patients with ANLL de novo who
have a history of occupational exposure to potentially
mutagenic substances. In the future. the type of leukemia
and the particular karyotypic pattern may be useful in
identifying a subset of patients with ANLL de novo whose
leukemia may be mutagen-induced
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