444 research outputs found
William Mitchell Opinion – Volume 19, No. 6, April 1977
No full textSelected Table of Contents SBA Elects Board / Loretta Frederick Dismissal Over Attendance Sparks Protest Women\u27s Conference Held / Barbara Gislason Spring Moot Court Competition / Helen Dovolis Quiz: Could you be a government attorney? Lawyers Slaughter English / Ronald Goldfarb 50 Lies for Next Year\u27s Freshmen Curriculum Still Changing / Jim Haigh Legal Services in Minnesota
Editorial Board
Michael Moriarity Loretta Frederick; Larry Klun; Jim Kronerhttps://open.mitchellhamline.edu/the-opinion/1052/thumbnail.jp
Teaching Contingent Valuation and Promoting Civic Mindedness in the Process
No full textEconomics majors are often assumed to lack civic mindedness. The purpose of this paper then is to demonstrate how by engaging students in the proper understanding of contingent valuation (CV) methodology and by evaluating a social service, we can improve student outcomes in two areas: increasing their competence in research design as well as in the process teaching them to consider the more unfortunate. Since students are really learning by doing in this prescribed process, the attractiveness of the teaching methodology is that the instructor substitutes direct learning and instruction on research design for one where students learn much of the subject matter through experimentation. This paper articulates the experiences of conducting a CV exercise with 49 second- and third-year economics students from the National University of Singapore (in the Environmental Economics course) during the month of October 2001.
sj-pdf-1-cmx-10.1177_10775595211055184 – Supplemental Material for Memory Accuracy After 20 Years for Interviews About Child Maltreatment
No full textSupplemental Material, sj-pdf-1-cmx-10.1177_10775595211055184 for Memory Accuracy After 20 Years for Interviews About Child Maltreatment by Yuerui Wu, Gail S. Goodman, Deborah Goldfarb, Yan Wang, Daisy Vidales, Lily Brown, Mitchell L. Eisen and Jianjian Qin in Child Maltreatment</p
sj-pdf-1-cpx-10.1177_21677026221081877 – Supplemental material for Adults’ Memory for a Maltreatment-Related Childhood Experience: Interview Protocols
No full textSupplemental material, sj-pdf-1-cpx-10.1177_21677026221081877 for Adults’ Memory for a Maltreatment-Related Childhood Experience: Interview Protocols by Deborah Goldfarb, Gail S. Goodman, Yan Wang, Ronald P. Fisher, Daisy Vidales, Lauren C. Gonzalves, Yuerui Wu, Dana Hartman, Jianjian Qin and Mitchell L. Eisen in Clinical Psychological Science</p
Axonal Na+ Channels Ensure Fast Spike Activation and Back-Propagation in Cerebellar Granule Cells
No full textIn most neurons, Na+ channels in the axon are complemented by others localized in the soma and dendrites to ensure spike back-propagation. However, cerebellar granule cells are neurons with simplified architecture in which the dendrites are short and unbranched and a single thin ascending axon travels toward the molecular layer before bifurcating into parallel fibers. Here we show that in cerebellar granule cells, Na+ channels are enriched in the axon, especially in the hillock, but almost absent from soma and dendrites. The impact of this channel distribution on neuronal electroresponsiveness was investigated by multi-compartmental modeling. Numerical simulations indicated that granule cells have a compact electrotonic structure allowing excitatory postsynaptic potentials to diffuse with little attenuation from dendrites to axon. The spike arose almost simultaneously along the whole axonal ascending branch and invaded the hillock the activation of which promoted spike back-propagation with marginal delay (< 200 mu s) and attenuation (< 20 mV) into the somato-dendritic compartment. These properties allow granule cells to perform sub-millisecond coincidence detection of pre- and postsynaptic activity and to rapidly activate Purkinje cells contacted by the axonal ascending branch
Cerebellar hyper-plasticity in the IB2 KO mouse model of autism
No full textAutism spectrum disorders (ASDs) are pervasive neurodevelopmental disorders that include syndromes with familial conditions. Among these, the Phelan-McDermid syndrome is associated with the co-deletion of SHANK3 and IB2 genes at the chromosome 22q terminus. Although much attention has been devoted to characterize SHANK3 mutations, very little is known about the role of IB2 in ASDs. The IB2 protein is expressed at synapses and takes part to the NMDA receptor (NMDAR) interactome in the postsynaptic densities. Experimental disruption of the IB2 gene in transgenic mice determined an enhanced NMDAR-mediated transmission at the mossy fiber-granule cell (MF-GrCs) synapse in the cerebellum. Moreover, IB2 knocked-out (IB2 KO) mice showed motor and cognitive deficits, making them a reliable ASD model [1]. Herein, we further investigated the synaptic and circuit modifications in IB2 KO mice. In particular, we addressed the potential alterations in the excitatory/inhibitory (E/I) balance and long-term potentiation (LTP) induction in the cerebellar granular layer of IB2 KO mice
FHF-independent conduction of action potentials along the leak-resistant cerebellar granule cell axon
No full textNeurons in vertebrate central nervous systems initiate and conduct sodium action potentials in distinct subcellular compartments that differ architecturally and electrically. Here, we report several unanticipated passive and active properties of the cerebellar granule cell's unmyelinated axon. Whereas spike initiation at the axon initial segment relies on sodium channel (Nav)-associated fibroblast growth factor homologous factor (FHF) proteins to delay Nav inactivation, distal axonal Na(v)s show little FHF association or FHF requirement for high-frequency transmission, velocity and waveforms of conducting action potentials. In addition, leak conductance density along the distal axon is estimated as < 1% that of somatodendritic membrane. The faster inactivation rate of FHF-free Navs together with very low axonal leak conductance serves to minimize ionic fluxes and energetic demand during repetitive spike conduction and at rest. The absence of FHFs from Navs at nodes of Ranvier in the central nervous system suggests a similar mechanism of current flux minimization along myelinated axon
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Crossings ::how road ecology is shaping the future of our planet /
No full text"An eye-opening and witty account of the global ecological transformations wrought by roads, from an award-winning author. Some 40 million miles of roadways encircle the earth, but we tend to regard them only as infrastructure for human convenience. In Crossings, Ben Goldfarb delves into the new science of road ecology to explore how roads have transformed our world. Millions of animals are killed by cars each day in the US alone, and roads fragment wildlife populations into inbred clusters, disrupt migration for creatures from antelope to salmon, allow invasive plants to spread and even bend the arc of evolution itself. But road ecologists are also seeking innovative solutions: Goldfarb meets with conservationists building bridges for mountain lions and tunnels for toads, engineers deconstructing logging roads, and citizens working to undo the havoc highways have wreaked upon cities. A sweeping, spirited and timely investigation into how humans have altered the natural world, Crossings also shows us how to create a better future for all living beings" -
Embargo de beneficios previsionales en la República Argentina : teoría y práctica
No full textEl artículo analiza la cuestión del embargo de los beneficios previsionales en la República Argentina, considerando el marco teórico y sus aspectos prácticos. El autor revela la existencia de una incongruencia entre la prohibición legal de embargo (salvo los casos de excepción de deudas por alimentos) y la efectiva traba de medidas cautelares y ejecutivas por deudas
comunes.The article analyzes the question of the embargo of retirement benefits in the Argentine Republic, considering the theoretical framework and its practical aspects. The author reveals the existence of an inconsistency between the legal prohibition of embargo (except for cases of exceptions of maintenance debts) and the effective blocking of precautionary and executive
measures for common debts.Fil: Goldfarb, Mauricio. Universidad Nacional del Nordeste. Facultad de Derecho y Ciencias Sociales y Políticas; Argentina
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