1,721,517 research outputs found
Stephen Mitchell & Peter Van Nuffelen (Ed.), Monotheism between Pagans and Christians in Late Antiquity, 2010
No full textSchamp Jacques. Stephen Mitchell & Peter Van Nuffelen (Ed.), Monotheism between Pagans and Christians in Late Antiquity, 2010. In: L'antiquité classique, Tome 82, 2013. pp. 441-442
Skeletal stem cell isolation and differentiation: Interdisciplinary strategies for skeletal tissue engineering
No full textStem cell based tissue engineering is viewed as a promising approach for orthopaedic reparative medicine and the application of microfluidic techniques for isolation and characterisation of individual skeletal stem cells is considered a potential source of cells for regenerative medicine. The studies described in this thesis aim to develop original techniques for isolation and characterisation of mesenchymal stem cells and to examine their possible uses in skeletal tissue engineering. These studies developed novel microfluidic technology using dielectrophoretic ring traps and sorting gates for isolation and recovery of specific cells according to immunofluorescent intensity. To date, the devices outlined in this work are limited by the small number of cells that can be isolated, but are capable of recovering established and primary cell populations with 100% purity for specific markers such as STRO-1, while also displaying potential for on-chip analysis and culture due to the ability to precisely control the device's microenvironment. This study has also investigated 28 day organotypic culture of 3D fetal femur-derived cell pellets at an air-liquid interface. It was demonstrated that addition of serum, ascorbate, dexamethasone and BMP-2 resulted in mimicry of in vivo femur development, while addition of ascorbate and TGF- phenotype, thus offering potential models for both cartilage and early bone development. Analysis of pellets demonstrated that significant pellet diameter at day 1 (greater than 0.8mm) is crucial for maintaining reproducible results in osteogenic and chondrogenic conditions. Furthermore, addition of BMP-2 to fetal femur-derived cells cultured in chemically defined media induced formation of a novel cobblestone cell morphology. Characterisation of the cobblestone cells demonstrated a primitive adipogenic phenotype as indicated by the lack of endothelial and haematopoietic marker expression including CD146, TIE2, CD34, and CD105 and upregulation of mesenchymal differ lipid. Overall these studies have offered a novel approach to stem cell isolation for characterisation and have furthered the knowledge of fetal femur-derived cell and their potential as an alternative cell source for skeletal tissue engineerin
Stephen Mitchell, Peter Van Nuffelen (eds.), Monotheism between Pagans and Christians in Late Antiquity (coll. Interdisciplinary Studies in Ancient Culture and Religion, 12), 2010
No full textAuwers Jean-Marie. Stephen Mitchell, Peter Van Nuffelen (eds.), Monotheism between Pagans and Christians in Late Antiquity (coll. Interdisciplinary Studies in Ancient Culture and Religion, 12), 2010. In: Revue théologique de Louvain, 44ᵉ année, fasc. 3, 2013. pp. 449-450
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Late Holocene archaeology in Namaqualand, South Africa: hunter-gatherers and herders in a semi-arid environment.
Full text linkThis study examines mid- to late Holocene Later Stone Age archaeological residues – specifically flaked stone artefacts, ostrich eggshell beads and pottery – from Namaqualand, north-western South Africa. Through its implication in all models so far proposed, Namaqualand is crucial to understanding the introduction of herding to the southern African subcontinent. Despite numerous publications on early herding, many key debates remain unresolved. The study focuses on the northern and central Namaqualand coastline, but sites from other parts of Namaqualand are also described. The stone assemblages are grouped according to variation in materials and retouch and then, along with data from ostrich eggshell beads and pottery, analysed graphically for temporal and other patterning. A cultural sequence is then presented. Using this sequence, key debates on early herding are explored and a hypothesis on its origins is constructed. Indigenous hunter-gatherers occupied the region throughout the Holocene and made Group 1 lithic assemblages from quartz and cryptocrystalline silica with frequent retouched tools primarily in cryptocrystalline silica. A new population – likely Proto-Khoekhoe-speaking hunter-gatherers with limited numbers of livestock – entered the landscape approximately 2000 years ago. They made Group 3 assemblages from clear quartz focusing on backed bladelets. Diffusion of stock and pottery among the local population occurred during this period. Later, c. AD 500, a new wave of migrants appeared. These last were the ancestors of the historically observed Khoekhoe pastoralists; they made Group 2 lithic assemblages on milky quartz without retouched tools. Bead diameter generally increases with time and contributes nothing to the debate. The pottery sequence is still too patchy for meaningful interpretation but differs from that elsewhere. Overall, the differing cultural signatures in western South Africa suggest that, although many questions will likely remain unanswered, a better understanding of southern African early herding will only be possible with a study addressing all regions simultaneously
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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