1,721,133 research outputs found

    Solubility of cefixime in aqueous mixtures of deep eutectic solvents from experimental study and modeling

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    Deep eutectic solvents (DESs) as green cosolvents can be added to water for increasing the solubility of poorly water-soluble drugs. In this study, the solubility of cefixime is studied in three aqueous solutions of DES, including choline chloride+malonic acid, choline chloride+urea, and choline chloride+glucose. The experiments are conducted in the temperature range of 293.15 K to 333.15 K, pressure of 0.1 MPa and different compositions of the DESs. The results show that adding DES to water increases the solubility of cefixime significantly. For instance, adding 6% (mol/mol) of choline chloride+malonic acid to water increases the cefixime solubility by more than 17 times. The DESs of choline chloride+malonic acid and choline chloride+urea are more effective cosolvents compared with the DES of choline chloride+glucose in increasing the mole fraction of cefixime. In addition, the solubility data are successfully correlated with the activity models of NRTL, Wilson and van Laar. The overall AARD% of the NRTL, Wilson and van Laar models in estimating the mole fraction of cefixime in aqueous solutions of the DESs are 3.88, 3.62 and 10.14, respectively

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Tunable Frequency Selective Surface Design Using Automated Random Optimization

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    We present an automated approach to design a high performance, tunable frequency selective surface (FSS). The main goal of this study is to provide the simultaneous optimization of the FSS structure in two states of the 4 incorporated varactors, aiming to get an acceptable polarization filtering and polarization control. Generally, microwave designs are dealing with a large amount of data and they depend on the engineer's experiences. In order to get rid of this dependency and providing a ready-to-fabricate layout, we propose an optimization-oriented method based on the random optimization (RO). The RO method is applied in an automated environment where HFSS and Matlab are collaborating together forming a co-simulation platform where the design parameters are optimized up to achieve suitable output performances

    Symmetry-breaking manipulation in the design of multifunctional tunable frequency selective surface

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    The design and characteristics of a PIN diode based tunable Frequency Selective Surface (FSS) is provided. Spatial filtering, polarization filtering and polarization control are all features the FSS exhibits in the considered 2-14 GHz frequency band. The proper symmetries required for the different features are explained and controlled by a holistic approach that includes the effects of the biasing network in the design. Symmetry breaking due to the presence of the biasing network used to bias the active elements are compensated by predistorsion of the initial geometry of the main structure that presents rotational symmetry. The proof of concept presented here allows extending the method to achieve proper design goals

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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