1,720,960 research outputs found
INTERNATIONAL MULTI-CENTRE DATA GATHERING FOR THE ESTABLISHMENT OF A DATABASE AND A RADIOLOGIC SOFTWARE THAT CAN BE USED FOR THE DIFFERENTIAL DIAGNOSIS OF BRAIN LESIONS OF AN INFECTIOUS ORIGIN
Design of a system to achieve diagnosis of brain lesions of suspected infectious origin from a database and a radiologic software
This project aims at creating an international database including an extensive collection of radiologic images of brain lesions and the relevant clinical, laboratory and microbiological data, and a software, to highlight and differentiate the minimal alteration in the radiologic footprint related to the local alterations of brain tissue produced by each individual pathogen that will become an objective diagnostic tool. Clinical parameters will be taken into account in defining a measure to estimate the probability that the difference between an image and a template be due to a specific pathological agent
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Development of a Software to Support Diagnosis of Brain Lesions of Suspected Infectious Origin Starting from an International Database and a Set of Radiologic Image Analysis Tools
Introduction: Brain infections are still a life threatening event in immunocompromised patients. Due to delays in etiological diagnosis, severe complications and related mortality rate are still too high. Brain Supporters is a multidisciplinary team working to develop a software tool which would be helpful for physicians trying to minimize this event in an innovative way.
Material and methods: All biological and clinical data we have selected, related to immunosuppressed patients with suspected or proven brain infectious diseases, and radiologic images (MR or CT) of their brain, will be collected in an international database freely accessible to transplant centres world-wide through a secure web site: www.brainsupporters.eu. Every case will be subject to a blind evaluation by two teams of specialists in radiologic and microbiology, in accordance with guidelines we have defined starting from an international criterion for proven diagnosis and then classified by aetiological agent.
Aim of the project: We aim to obtain the probability of presence for any pathological agent, starting from the most spread, analysing the "radiologic footprint" of lesions and clinical and biological data of the subject to eventually minimize the variability due to the different characteristics of the host, his immunosuppressant therapies and clinical condition.
We have designed and implemented the database and chosen a dicom software with an html5 interface to manage radiologic images directly from the web site, even from a tablet and without installing other tools. We are developing and testing a software package we will use for data and image analysis.
Conclusions: The development of a software as a diagnostic supportive tool for physicians could lead to an early diagnosis, gain of time and greater management of brain infectious diseases in immunocompromised patients. A little step to ameliorate their condition
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
The Brain Supporters Project: a system to support diagnosis of brain lesions of suspected infectious origin, in transplanted patients, starting from a database and a set of radiologic image analysis tools
Brain infections in patients undergoing haemopoietic stem cell transplants or solid organ transplants are
very complex to deal with and lead to higher mortality rates. The Brain Supporters Project aims at creating an international database of radiologic images of brain lesions together with clinical, laboratory
and microbiological data. Starting from this database we’ll develop an ‘intelligent’ software that through the use of multidimensional analysis techniques, variational methods and classification
procedures, can detect, highlight and differentiate the minimal and yet peculiar differences in the ‘radiologic footprint’ connected with the local alterations of brain tissue produced by each individual pathogen, thus becoming an objective diagnostic aid.
Material and methods.
An internet site has been created, www.brainsupporters.eu, freely accessible to transplant centres world-wide.
The radiologic images with confirmed diagnosis collected in the database(hosted on CNR-ISMAR, Venice) will then be subject to a blind evaluation by a team of specialists.
Results.
The images will then be classified by aetiologic agent and subsequently by age group and by clinical characteristics of the patients.
It will thus be possible to evaluate if and how the ‘radiologic footprint’ of lesions due to the same pathogen is modified depending on the different characteristics of the host.
Discussion and conclusions.
The database is now online. We are sending invitations to every relevant centre, inserting our data in the
database and we started working on data analysis tools with the following objective: obtain the probability of presence of the most spread pathological agents
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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