1,721,509 research outputs found
Statements Signed by Cardinal Mingoli and Pompilj
No full textTypescript statements signed by Cardinal [Mingoli] and Cardinal Pompilj, of the Vicariate of Rome, Via della Pigna 13 A, Rome, stating approval of the accommodation allotted to the Sisters of St. John of God in the College, and granting permission for a number of sisters to be introduced to the College. [11 May – 2 June 1923
Risk factors for unfavourable postoperative outcome in patients with Crohn's disease undergoing right hemicolectomy or ileocaecal resection. An international audit by ESCP and S-ECCO
No full textAim Patient- and disease-related factors, as well asoperation technique, all have the potential to impact onpostoperative outcome in Crohn’s disease. The availableevidence is based on small series and often displays con-flicting results. The aim was to investigate the effect ofpreoperative and intra-operative risk factors on 30-daypostoperative outcome in patients undergoing surgeryfor Crohn’s disease.Method This was an international prospective snapshotaudit including consecutive patients undergoing righthemicolectomy or ileocaecal resection. The study anal-ysed a subset of patients who underwent surgery forCrohn’s disease. The primary outcome measure was theoverall Clavien–Dindo postoperative complication rate.The key secondary outcomes were anastomotic leak,reoperation, surgical site infection and length of stay inhospital. Multivariable binary logistic regression analyseswere used to produce odds ratios and 95% confidenceintervals.Results In all, 375 resections in 375 patients wereincluded. The median age was 37 and 57.1% werewomen. In multivariate analyses, postoperative compli-cations were associated with preoperative parenteralnutrition (OR 2.36, 95% CI 1.10–4.97), urgent/expe-dited surgical intervention (OR 2.00, 95% CI1.13–3.55) and unplanned intra-operative adverseevents (OR 2.30, 95% CI 1.20–4.45). The postopera-tive length of stay in hospital was prolonged in patientswho received preoperative parenteral nutrition (OR 31,95% CI 1.08–1.61) and those who had urgent/expe-dited operations (OR 1.21, 95% CI 1.07–1.37).Conclusion Preoperative parenteral nutritional support,urgent/expedited operation and unplanned intra-operativeadverse events were associated with unfavourable postoper-ative outcome. Enhanced pre operative op timization andimproved planning of operation pathways and timings mayimprove outcomes for patients
Il dolore addominale acuto.
No full textLibro per gli studenti del Corso di Laurea in Medicina e Chirurgi
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Clinical outcomes of patients with hollow viscous injuries after a blunt abdominal trauma: the influence of diagnostic and therapeutic delay and the predictive role of BIPS
No full textDear Sir,
We read with great interest the article by Harmston et al. about the clinical effects of delayed treatment of hollow vis- cous injuries (HVI) due to blunt abdominal trauma [1]. The results of their systematic review confirmed the diagnostic challenge of these lesions with a frequent delay of surgical treatment. The Cox regression analysis demonstrated that an early operation significantly decreased the mortality rate (1 out of 11 studies) while a delayed operation increased the morbidity rate (5 out of 9 studies). Confounding factors were the definition of delayed intervention, due to different time intervals considered in the different study, and the presence of other organ additional injuries. The authors underlined the importance of an early treatment to improve the outcome of patients with HVI after a blunt abdominal trauma, but at the same time, claimed the need of a consensus on the defi- nition of delayed intervention, and of future investigations on early detection and treatment of patients with isolated viscous injury.
In 2017, we published the results of our experience with 169 patients who presented a traumatic HVI [2]. Our research highlighted the unfavorable effect on clinical out- comes of delayed diagnosis and surgical treatment. Mortality and morbidity rates were 15.9% and 36.1%, respectively, and the mean length of staying was 23 ± 7 days. Delay of treat- ment was not a prognostic indicator for postoperative mortal- ity, while morbidity was strongly and independently related to an early leucocytosis and to a delay of treatment > 6 h. The mean delay of treatment for patients with HVI who
* Andrea Mingoli [email protected]
1 Department of Surgery, Sapienza University, Policlinico Umberto I, Rome, Italy
2 Emergency Department, Sapienza University, Policlinico Umberto I, Rome, Italy
developed postoperative complications was 22.5 ± 3.6 h, compared to 6.1 ± 1.4 h for uncomplicated patients.
In the attempt to identify predictive cut-off and threshold values in treatment delay for morbidity, through the ROC curve analysis, we observed positive predictive values for postoperative morbidity of 73.5% and 100% for a treatment delay of 12 and 24 h, respectively.
In the group of patients with HVI after a blunt abdominal trauma, we tested also the predictive value of the Bowel Injury Predictive Score (BIPS). This score was recently introduced [3] to predict the risk of bowel injury when more than two of the following parameters are present at ER admission: (1) high-grade mesenteric injury at admission CT scan, (2) increased WBC (> 17,000), and (3) abdominal tenderness. BIPS resulted in an independent predictor of outcome and patients with a value > 2 had a significant prob- ability (p = 0.029) to develop a postoperative complication compared to patients with a BIPS < 2.
In conclusion, in our hands, a delay of diagnosis and treatment of HVI after a blunt abdominal trauma was an independent predictor of morbidity, strongly affecting the postoperative course. Adoption of BIPS seems very useful to increase the diagnostic sensitivity and reduce the treatment delay to less than 6–12 h after ER admission
- …
