169,954 research outputs found

    Coping styles in individuals with different severity of hypertension.

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    The strategies that usually people adopt to cope with stressful events, namely coping (C) style, may affect blood pressure. Generally, hypertension (H) is positively related to emotion-oriented maladaptive C strategies and negatively related to task-oriented C styles. However, no author investigated the relationship between C strategies and H severity. This study was aimed to assess whether the severity of the cardiovascular health status of the participants is associated with specific C strategies. Participants were recruited at the Center for the Treatment of Hypertension (H) of the Policlinico Umberto I in Rome. Seven hundred sixty-one individuals (M/F: 330/431; mean age: 60.83±11.63 years) agreed to participate in the study (65% of the contacted people). The study took place over the period 2014-15. Participants were split into five groups: 1) healthy people (N=158); 2) individuals with untreated H (N=160); 3) individuals under antihypertensive drug treatment (N=157); 4) individuals with H resistant to drug therapy (N=159); individuals suffering from both H and heart diseases (N=127). To assess the C strategies, the Coping Inventory for Stressful Situation was used. One-way ANOVAs considering the Group as the independent variable was carried out on each of the C strategies (emotion-oriented C, task-oriented C, avoidance-oriented C). The results showed a significant effect for the task-oriented C (F4,745=4.03; p<.003), indicating that individuals affected by both H and heart diseases make less use of task-oriented C strategies compared to the healthy group (p<.01), the individuals under antihypertensive drug treatment (p<.01), and the group with H resistant to drug therapy (p<.03). These findings confirm the relationship between C and H, underlining how patients with a greater severity of H make less use of appropriate C strategies. These results suggest the importance of implementing interventions aimed at promoting appropriate C strategies in patients with H

    A Generalized Heckmann-Schucking cosmological solution in the presence of a negative cosmological constant

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    An exact solution of the Einstein equations for a Bianchi-I universe in the presence of dust, stiff matter and a negative cosmological constant, generalising the well-known Heckmann-Schucking solution is presented. This solution describes a universe existing during a finite period of cosmic time, where the beginning and the end of its evolution are characterized by the presence of Kasner type cosmological singularities

    The relevance of social dreaming for action research: exploring jail workers’ unconscious thinking of the changes in the prison organization

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    The contribution focuses on how dreams can be investigated as social phenomena in a manner which illuminates the role of the individual in a particular group and elucidates unconscious group processes in an organization. The article presents an experience of adopting Lawrence’s social dreaming (SD) matrices in a new a specific field: an Italian prison which has shifted in the last two decades from a punitive to a rehabilitative mission. The aim of the experience was twofold: i) to help jail workers, through a formative experience, gaining a deeper understanding of how the new prison environment influences their emotional experience and work functioning; ii) to collect the emotional climate, the feelings, and the critical issues among the prison staff, in order to gain insights for the authorities responsible for the regulation of correctional facility. The experience of SD included 4 matrices, involving a total of 12 participants: 7 prison officers and 5 educators. The main thematic areas emerged from the matrices are related to: trust, competence, professional identity, separateness and privacy, safety, and to the gender differences. All the themes are presented and discussed, along with dreams and free associations. The present work is, to our knowledge, the first attempt to apply the tool of social dreaming to the context of correctional facility all over the world. The described experience might serve as an example of the applicability of this mode of analytic exploration to institutions or organizations, and the contribution opens to reflection and some implications

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Adattamento Italiano degli Standard di Servizio delle Comunità Terapeutiche per l’Infanzia e l’Adolescenza

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    Il Community of Communities (C. of C.) è un programma di miglioramento della qualità e di accreditamento tra pari per le Comunità Terapeutiche (CT), attivo nel Regno Unito, ma aperto anche a partecipazioni internazionali, avviato nel 2002 dal Royal College of Psychiatrist su iniziativa dell’Association of Therapeutic Communities (ATC). Il Community of Communities, in questi dieci anni di attività, ha costruito un network scientifico-professionale fondato su di una sere di programmi di miglioramento di qualità e di accreditamento tra pari e sviluppato dal College Centre for Quality Improvement (CCQI) del Royal College of Psychiatrist, che rappresenta una delle più importanti matrici socio-organizzative delle Best Practices sviluppate a livello internazionale sulle Comunità Terapeutiche. Fino ad oggi, il C. of C. ha prodotto diverse edizioni di Service-Standard per comunità terapeutiche specializzate nella cura in diversi setting istituzionali tra i quali due edizioni di Service-Standard per minori ed adolescenti. La seconda edizione curata da John O’Sullivan & Sarah Paget è quella qui tradotta ed adattata alla cultura italiana, con l’approvazione, nella sua stesura finale, del Community of Communities Project Team e del Community of Communities Children and Young People’s Reference Group

    Complex rearrangement of chromosomes 7q21.13-q22.1 confirms the ectrodactyly-deafness locus and suggests new candidate genes

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    Complex chromosomal rearrangements with more than two breakpoints are rare. We report on a 5-year-old girl, evaluated because of psychomotor delay, ectrodactyly of right hand and feet, craniofacial dysmorphic features, cleft palate, deafness, and tetralogy of Fallot. A standard karyotype suggested a small intrachromosomal duplication of chromosome 7q. The chromosomal rearrangement was characterized by mBAND, which disclosed a reciprocal interstitial translocation t(7;8)(q21q22;q23q24). FISH analysis and array-CGH analysis showed a paracentric inversion of 7q and a microdeletion of 7q21.13. The parents had normal chromosomes. The deletion found in the present patient confirms that candidate region of ectrodactyly-deafness (OMIM 220600) maps to 7q21 and suggests new candidate genes for that disorder. This patient also had facial features reminiscent of tricho-rhino-phalangeal syndrome and one chromosome breakpoint involved band 8q24, a locus for this disorder. In addition, FOG1 gene maps to 8q23 and has been implicated in a subset of subjects with tretralogy of Fallot. We suggest that the aberration of 8q may have contributed to her facial and cardiac findings

    Mitomycin C in highly myopic eyes - Author reply

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    Ophthalmology. 2005 Feb;112(2):208-18; discussion 219. Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes. Gambato C, Ghirlando A, Moretto E, Busato F, Midena E. SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy. Abstract PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes. DESIGN: Prospective, double-masked, randomized clinical trial. PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia. METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months). MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH. RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively). CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK. Comment in Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
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