1,721,304 research outputs found
BeppoSAX observation of the microquasar GRS 1915+105: spectral and timing behavior in the ρ class
No full textBeppoSAX observed GRS1915+105 on October 2000 when the source was mainly in the ρ class characterized by bursts with recurrence time between 40 and 100 s. The X-ray flux showed a general increase during the observation with a complex behavior. We present some results on the time and spectral analysis of MECS and PDS data in time intervals correspondentto a satellite orbit. © 2010 American Institute of Physics
Predictor of oncological and neurological outcomes after surgery in patients with thymomatous class III myasthenia gravis.
No full textThymomatous myasthenia gravis represents a peculiar and severe disease. This study is aimed at evaluating if features specifically related to the neoplasm (i.e.stage, histology, biology) may be significant predictors of neurological outcome after thymomectomy and viceversaneurological variables can affect the neoplasm evolution in a precise clinical class (Class III according to the Myasthenia Gravis Foundation of America) of myasthenia gravis.
Methods: We performed a retrospective analysis of 35 patients (16 male, 19 female) with thymoma and class III myasthenia gravis undergoing extended transternal thymectomy plus thymomectomy between 1985 and 2005.
Class III was identified as a moderate weakness predominantly affecting limb or axial muscles (type a) or oropharyngeal muscles (type b). Patients operated before 2000 and therefore classified according to the Osserman’s classification were retrospectively re-classified. Oncological endpoints was disease-free survivals. Neurolgical out come was complete stable remission. As oncological predictors of poor outcome were considered age (>55), sex (male), Masaoka stage (II-III), histology according World Health Organization (B2-B3), incomplete resection and cell-cycle protein (p53 high-, p21 low-, p27 low) and glucose transporter-1 and vascular endothelial growth factor expressions. Neurological poor predictors were sex (male), symptom-duration (<12 months), quality of life levels (physical and mental component summaries SF-36 below median value), Myasthenia gravis score, steroid-use, oropharyngeal involvement, histology (B2-B3), hyperplastic residual thymus and evidence of ectopic thymic tissue.
Results: There was no perioperative mortality. Disease-free survival rate were 67% at 5 and 56% at 10 years, respectively. At univariate analysis significant negative predictors were stage II-III (p=0.041), incomplete resection (p=0.019), B2-B3 histology (p=0.007) and cell-cycle protein expression (p=0.001), the latter resulting as the sole predictor at multivariate (p=0.003). Complete stable remission rate was 52% at 10 and 66% at 15 years, respectively. At univariate analysis significant negative predictors of complete stable remission were those related to the tumor and namely B2-B3 histology (p=0.021), incomplete resection (p=0.007) and cell-cycle protein expression (p=0.032). Traditional factors resulted marginal significant or non significant. No factor prevailed at multivariate analysis.
Conclusion: Incomplete resection of thymoma, B2-B3 histology and cell-cycle protein expression resulted the most significant predictors for both oncological and neurological poor outcome. Whereas traditional neurological factors resulted marginally or non significantly affecting the neurological outcome.These findings entails that thymomatous myasthenia should be considered a different neurological entity from the nonthymomatous one
A multicomponent model for the optical to gamma-ray emission from the Crab pulsar
No full textarXiv:astro-ph/070125
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Spectral and timing properties of the X-ray emission from the millisecond pulsar PSR B1821-24
No full text
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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