537 research outputs found

    Chemical specificity in short-chain fatty acids and their analogues in increasing osmotic fragility in rat erythrocytes in vitro.

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    We examined the role of the chemical specificity of short-chain fatty acids (SCFAs) and their derivatives in increasing osmotic fragility (OF) in rat red blood cells (RBCs). Except for formic acid, normal SCFAs with 2 to 8 carbons increased the OF in rat RBCs with increasing number of hydrocarbons in a dose-dependent manner. Replacement of the carboxylic group with sulfonic group inhibited, but did not abolish, the SCFA-mediated increase in OF. Introduction of another carboxylic group (dicarboxylic acids) completely abolished the SCFA-mediated increase in OF. Transformation of the hydrocarbon chains in SCFAs from straight to branched or cyclic chains affected the degree of the OF-increasing effect. Introduction of double- or triple-carbon bonds to the hydrocarbon chain in parent SCFAs did not affect the increase in OF. Both hydrophilic (carboxylic group) and hydrophobic elements (hydrocarbons) at opposite sides of a molecule were required to affect the RBC membrane, and the size and form of hydrophobic element were important factors in determining the SCFA-mediated increase in OF. The hydrocarbon chains probably enter the plasma membrane, with the hydrophilic carboxylic base remaining outside of the membrane, and interact with phospholipid in cell membrane and disturb the structure of lipid layer resulting in the increase in OF in the rat RBCs

    Erratum: The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition (Proceedings of the National Academy of Sciences of the United States of America (2020) 117 (4180-4187) DOI: 10.1073/pnas.1913481117)

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    Correction for “The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition,” by Simone F. Glaser, Andreas W. Heumüller, Lukas Tombor, Patrick Hofmann, Marion Muhly-Reinholz, Ariane Fischer, Stefan Günther, Karoline E. Kokot, David Hassel, Sandeep Kumar, Hanjoong Jo, Reinier A. Boon, Wesley Abplanalp, David John, Jes-Niels Boeckel, and Stefanie Dimmeler, which was first published February 7, 2020; 10.1073/pnas.1913481117 (Proc. Natl. Acad. Sci. U.S.A. 117, 4180-4187). The authors note that Hitoshi Okada should be added to the author list between Karoline E. Kokot and David Hassel. Hitoshi Okada should be credited with providing mice. The corrected author line, affiliation line, and author contributions appear below. The online version has been corrected

    Surface chemical modification of carbon nanowalls for wide-range control of surface wettability

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    Carbon nanowalls (CNWs) are self-assembled, free-standing, few-layered graphenenano-structures with large surface area, and thin graphene edges. For their application to nanobiotechnology, the effects of chemisorbed species on surface wettability were investigated. The surfaces of as-grown CNWs obtained using CH4/H2 mixture were hydrophilic. After Ar atmospheric pressure plasma treatments for up to 30 s, the contact angles of water droplets on the CNWs decreased from 51° to 5°, owing to a result of oxidation only at edges and surface defects. They increased up to 147° by CF4 plasma treatment at low pressure. The wide-range control of surface wettability of CNWs was realized by post-growth plasma treatments. We also demonstrated detection of bovine serum albumin using surface-modified CNWs as electrodes

    ERRATA

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    Volume and issue: Vol.6, No.7 (2011)Page: pp.317-322Title: Contribution of Slip and Cleavage in Friction and Wear at (10-14) Surface of Magnesite (MgCO3) CrystalAuthor(s): Kaori Niki, Mai Kobayashi and Hitoshi ShindoVolume and issue: Vol.7, No.1 (2012)Page: pp.8-12Title: Frictional Asymmetry and Wear Pattern Formation by Slip and Cleavage Detected at Directional r {10-14} Face of Calcite (CaCO3)Author(s): Kaori Niki, Mai Kobayashi and Hitoshi Shind

    Letter from John Lancaster, Unit President, A.I.F.D., January 29, 1970

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    Letter from John Lancaster, Chairman, American Institute of Floral Designers (A.I.F.D) addressed to the florists who are interested in attending the Yoke Kuromi Memorial Dinner.This collection contains two photograph albums and material related to Hitoshi "Yoke" Kuromi and Corrine Nobuko Nishimura Kuromi. Subjects in the collection include the Kuromi family, the Gila River incarceration camp, and hot rods, and classic cars

    Letter from John Lancaster, Unit President, A.I.F.D., January 29, 1970

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    Letter from John Lancaster, Unit President, American Institute of Floral Designers (A.I.F.D.), possibly addressed to the Southern California Teleflora Unit about the funeral for Yoke Kuromi.This collection contains two photograph albums and material related to Hitoshi "Yoke" Kuromi and Corrine Nobuko Nishimura Kuromi. Subjects in the collection include the Kuromi family, the Gila River incarceration camp, and hot rods, and classic cars

    Meeting minutes for Yoke Kuromi's memorial dinner, May 20, 1970

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    A copy of the meeting minutes for Yoke Kuromi's Memorial Dinner.This collection contains two photograph albums and material related to Hitoshi "Yoke" Kuromi and Corrine Nobuko Nishimura Kuromi. Subjects in the collection include the Kuromi family, the Gila River incarceration camp, and hot rods, and classic cars

    Letter from John Lancaster, General Chairman, A.I.F.D.

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    Letter from John Lancaster, General Chairman for the American Institute of Floral Designers (A.I.F.D.) regarding the Yoke Kuromi Memorial Dinner.This collection contains two photograph albums and material related to Hitoshi "Yoke" Kuromi and Corrine Nobuko Nishimura Kuromi. Subjects in the collection include the Kuromi family, the Gila River incarceration camp, and hot rods, and classic cars

    Meeting minutes for Yoke Kuromi's memorial dinner

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    Meeting minutes for Yoke Kuromi's Memorial Dinner.This collection contains two photograph albums and material related to Hitoshi "Yoke" Kuromi and Corrine Nobuko Nishimura Kuromi. Subjects in the collection include the Kuromi family, the Gila River incarceration camp, and hot rods, and classic cars
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