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Fatal anaphylactic shock due to a dental impression material
Materials used for dental impressions are usually safe. This study describes a case of
fatal anaphylaxis that appeared immediately after the oral mucosa came into contact
with an alginate paste used for dental impressions. The cadaveric examination and
the poslmortem toxicology report confirmed that the cause of death was anaphylactic
shock. The patient was affected by both cardiovascular and lung dlseases that
worsened the condition and forbade the use of epinephrine. To the authors'
knowledge, dental impression materials, and alginate in particular, have not been reported previously as being a cause of anaphylaxi
Allergic diseases in the elderly: biological characteristics and main immunological and non-immunological mechanisms
Differences in the behavior of advanced glycation end products and advanced oxidation protein products in patients with allergic rhinitis.
BACKGROUND: The presence of oxidative stress in patients with asthma is well
documented; however, the role of oxidative stress in allergic rhinitis has
received less attention, although it is likely to be similar to that observed in
patients with asthma. Advanced glycation end products (AGEs) and advanced
oxidation protein products (AOPPs) are compounds formed by the transformation of
macromolecules, including proteins, which can serve as densitometric markers of
oxidative stress and inflammation in several diseases.
OBJECTIVE: The aim of this study was to investigate the role of AGEs and AOPPs as
new markers of oxidative stress and inflammation in patients affected by allergic
rhinitis.
METHODS: AGE and AOPP levels were determined in the sera of 25 patients with
allergic rhinitis and 64 healthy controls. AGEs and AOPPs were detected using
spectrofluorimetry and spectrophotometry, respectively.
RESULTS: AGE levels in patients were significantly higher than those in controls
(P < .0001). These levels were not affected by the presence of asthma. No
statistically significant differences were found between AOPP levels in patients
or controls (P = .38).
CONCLUSIONS: Formation of AGEs and AOPPs may be accelerated in immunological and
respiratory disorders such as asthma. Depending on the marker evaluated, the
presence or absence of oxidative stress in allergic rhinitis is controversial. To
our knowledge, this is the first study showing the possible involvement of AGEs
in allergic rhinitis. The different behavior observed for these 2 biomarkers is
very likely due to the activation of specific related biochemical pathways (eg, the myeloperoxidase pathway) associated with the condition under study
Bilateral cyclic cheek lesions related to premenstrual syndrome: a multifactorial pathogenesis?
Introduction Cheek biting is a chronic, usually innocuous,
self-inXicted injury that often occurs as a parafunctional
habit.
Case report We report an unusual case of bilateral cyclic
cheek lesions in a 34-year-old woman characterized by
hyperkeratinization near the biting edges of the teeth and
hematic lesions accompanied by a cheek swelling sensation,
without pain and burning. The lesions coincided with
a premenstrual syndrome, characterized by Xuid retention Introduction Cheek biting is a chronic, usually innocuous,
self-inXicted injury that often occurs as a parafunctional
habit.
Case report We report an unusual case of bilateral cyclic
cheek lesions in a 34-year-old woman characterized by
hyperkeratinization near the biting edges of the teeth and
hematic lesions accompanied by a cheek swelling sensation,
without pain and burning. The lesions coincided with
a premenstrual syndrome, characterized by Xuid retentionrelated
symptoms, such as leg swelling, breast tenderness,
bloatedness with abdominal girth variation and weight gain.
Conclusions We concluded that the excessive water
retention caused a little widespread swelling, present at
cheeks level also, that associated with a temporary bruxism
(perhaps related to psychological stress typical of premenstrual
syndrome) was probably responsible for the cyclic
cheek lesions. Therefore, an oral exam by the womens
health care provider may be valuable in cases of premenstrual
syndrome
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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