1,721,065 research outputs found
Chronic Systolic Heart Failure, Guideline-Directed Medical Therapy, and Systemic Hypotension-Less Pressure but Maybe More Risk (Does This Clinical Scenario Need More Discussion?)
Many clinical trials have demonstrated the survival benefit of medication regimens that modulate the neurohormonal activation that occurs with chronic heart failure (HF). These medications, however, also commonly lower systemic blood pressure (BP). Low arterial BP in patients with chronic HF has been shown to be an independent predictor of increased mortality. Given this apparent paradox in therapeutic goals (treat aggressively but keep BP from going too low), how low should we allow systemic BP to go as a result of our medication regimens before we compromise the proven benefits of such drug therapy? Or is the association between the BP-lowering effects of standard therapy and outcomes in HF even meaningful clinically? It is from this perspective that the merits, potential clinical implications, and the relevant published literature pertaining to this patient and practice management issue will be discussed. © 2009 Elsevier Inc. All rights reserved.Aaronson KD, 1997, CIRCULATION, V95, P2660; ADAMS JF, 2006, J CARD FAIL, V12, P10; Anand IS, 2007, J AM COLL CARDIOL, V49, P32, DOI 10.1016-j.jacc.2006.04.109; Anand IS, 2008, CIRC-HEART FAIL, V1, P34, DOI 10.1161-CIRCHEARTFAILURE.107.736975; Canesin Manoel F, 2002, Arq Bras Cardiol, V78, P83, DOI 10.1590-S0066-782X2002000100007; Chobanian AV, 2003, HYPERTENSION, V42, P1206, DOI 10.1161-01.HYP.0000107251.49515.c2; COHN JN, 1973, AM J MED, V55, P351, DOI 10.1016-0002-9343(73)90135-6; Cowie MR, 2000, HEART, V83, P505, DOI 10.1136-heart.83.5.505; CRUICKSHANK JM, 1992, EUR HEART J, V13, P39; De Pasquale CG, 2005, EUR J HEART FAIL, V7, P888, DOI 10.1016-j.ejheart.2004.12.012; FARNETT L, 1991, JAMA-J AM MED ASSOC, V265, P489, DOI 10.1001-jama.265.4.489; Fonarow GC, 2005, JAMA-J AM MED ASSOC, V293, P572, DOI 10.1001-jama.293.5.572; GHALI JK, 1992, AM HEART J, V123, P993, DOI 10.1016-0002-8703(92)90709-5; Gheorghiade M, 2006, JAMA-J AM MED ASSOC, V296, P2217, DOI 10.1001-jama.296.18.2217; Goldenberg I, 2007, J AM COLL CARDIOL, V49, P1427, DOI 10.1016-j.jacc.2006.11.042; GOULD KL, 1985, CIRC RES, V57, P341; Herlitz J, 2002, J CARD FAIL, V8, P8, DOI 10.1054-jcaf.2002.30735; Hunt Sharon Ann, 2005, J Am Coll Cardiol, V46, pe1, DOI 10.1016-j.jacc.2005.08.022; Ingelsson E, 2006, JAMA-J AM MED ASSOC, V295, P2859, DOI 10.1001-jama.295.24.2859; Kannel WB, 2004, AM J CARDIOL, V94, P380, DOI 10.1016-j.amjcard.2004.04.043; Kihara M, 1998, AGE AGEING, V27, P551, DOI 10.1093-ageing-27.5.551; Kikuya M, 2007, CIRCULATION, V115, P2145, DOI 10.1161-CIRCULATIONAHA.106.662254; Koelling TM, 2004, AM HEART J, V147, P74, DOI 10.1016-j.ahj.2003.07.021; Lee J, 2006, WOMEN HIST REV, V15, P83, DOI 10.1080-09612020500440903; LEVINE TB, 1982, AM J CARDIOL, V49, P1659, DOI 10.1016-0002-9149(82)90243-0; Levy WC, 2006, CIRCULATION, V113, P1424, DOI 10.1161-CIRCULATIONAHA.105.584102; Mark DB, 1997, AM J CARDIOL, V80, pH33, DOI 10.1016-S0002-9149(97)00818-7; Messerli FH, 2006, ANN INTERN MED, V144, P884; Metra M, 2005, EUR HEART J, V26, P2259, DOI 10.1093-eurheartj-ehi386; Mosterd A, 2001, EUR HEART J, V22, P1318, DOI 10.1053-euhj.2000.2533; OCONNELL JB, 1994, J HEART LUNG TRANSPL, V13, pS107; Redfield MM, 2003, JAMA-J AM MED ASSOC, V289, P194, DOI 10.1001-jama.289.2.194; Rouleau JL, 2004, J AM COLL CARDIOL, V43, P1423, DOI 10.1016-j.jacc.2003.11.037; Senni M, 1999, ARCH INTERN MED, V159, P29, DOI 10.1001-archinte.159.1.29; Shin J, 2007, J CARD FAIL, V13, P656, DOI 10.1016-j.cardfail.2007.04.013; Taylor AL, 2004, NEW ENGL J MED, V351, P2049, DOI 10.1056-NEJMoa042934; Williams BR, 1999, ANN PHARMACOTHER, V33, P149, DOI 10.1345-aph.1742466
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
Author-wise bibliometric analysis based on entropy.</p
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