77 research outputs found

    Le Bijoutier

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    Le Bijoutie

    Catherine BON

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    corpus du GAR

    A Brief History of Human Time - Cross-verified Dataset

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    This cross-verified dataset contains 2.2 million individuals, it can be used for research purposes. This dataset is linked to the following paper that should be cited directly instead of the data itself: Morgane Laouenan, Palaash Bhargava, Jean-Benoît Eyméoud, Olivier Gergaud, Guillaume Plique, Etienne Wasmer (2022) A cross-verified database of notable people, 3500BC-2018AD, Scientific Data, June 2022. Bibtex: @article{bhht3, author = {Laouenan, Morgane and Bhargava, Palaash and Eyméoud, Jean-Benoît and Gergaud, Olivier and Plique, Guillaume and Wasmer, Etienne}, title = {A cross-verified database of notable people, 3500BC-2018AD}, journal = {Scientific Data}, publisher = {Nature Publishing Group}, year = {2022}, month = {Jun}, day = {09}, volume = {9}, number = {1}, pages = {290}, issn = {2052-4463}, doi = {10.1038/s41597-022-01369-4}, url = {https://doi.org/10.1038/s41597-022-01369-4} } This dataset is subject to CC-BY-SA licensing. </p

    A Brief History of Human Time - Codes & Datasets

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    This compressed folder includes the code used for scraping and building the dataset, the intermediate datasets and the (not cross-verified) exhaustive dataset. This dataset is linked to the following paper that should be cited directly instead of the data itself: Morgane Laouenan, Palaash Bhargava, Jean-Benoît Eyméoud, Olivier Gergaud, Guillaume Plique, Etienne Wasmer (2022) A cross-verified database of notable people, 3500BC-2018AD, Scientific Data, June 2022. Bibtex: @article{bhht3, author = {Laouenan, Morgane and Bhargava, Palaash and Eyméoud, Jean-Benoît and Gergaud, Olivier and Plique, Guillaume and Wasmer, Etienne}, title = {A cross-verified database of notable people, 3500BC-2018AD}, journal = {Scientific Data}, publisher = {Nature Publishing Group}, year = {2022}, month = {Jun}, day = {09}, volume = {9}, number = {1}, pages = {290}, issn = {2052-4463}, doi = {10.1038/s41597-022-01369-4}, url = {https://doi.org/10.1038/s41597-022-01369-4} } The intermediate files as well as the exhaustive database are not cross-verified and should not be used directly or under the full responsibility of users. All datasets included in this folder are subject to CC-BY-SA licensing. </p

    Author response

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    The adult frog retina retains a reservoir of active neural stem cells that contribute to continuous eye growth throughout life. We found that Yap, a downstream effector of the Hippo pathway, is specifically expressed in these stem cells. Yap knock-down leads to an accelerated S-phase and an abnormal progression of DNA replication, a phenotype likely mediated by upregulation of c-Myc. This is associated with an increased occurrence of DNA damage and eventually p53-p21 pathway-mediated cell death. Finally, we identified PKNOX1, a transcription factor involved in the maintenance of genomic stability, as a functional and physical interactant of YAP. Altogether, we propose that YAP is required in adult retinal stem cells to regulate the temporal firing of replication origins and quality control of replicated DNA. Our data reinforce the view that specific mechanisms dedicated to S-phase control are at work in stem cells to protect them from genomic instability

    Role of saturated covers as oxygen buffers in cold climates

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    [T]his report explores a hybrid-applied solution: the use of saturated covers, which involve lifting an elevated water table into a tailing impoundment that maintains saturation within the tailing profile without allowing excess water directly along the surface of the embankment. The objective of this project is to evaluate the efficacy of saturated covers in Northern regions by testing oxygen diffusion in a series of experiments with two levels of saturation using an instrumented column. While there has been some research detailing the beneficial use of saturated covers, such as in the Oxygen diffusion in saturated covers methodology and literature review (Gagne Turcotte et al., 2020) completed prior to this lab scale study, the methodology used within this study relied heavily on prediction variables/models: De and Kr, but these proved to be more complicated than expected (Gagne Turcotte et al., 2020). Additionally, mine tailings by nature are rather unique and each sample of tailings has its own unique characteristics that need to be accounted for. Thus, the creation of this methodology occurred, with a specific emphasis on applied methods.--from IntroductionPublication is a an outcome of the oxygen diffusion in saturated covers project

    Beneficios y costes en el uso de un intérprete profesional en el ámbito médico: meta-análisis de 35 estudios en los estados unidos

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    Las barreras del idioma pueden tener consecuencias negativas para la salud de los pacientes que no hablan inglés y pueden además traer aparejado un aumento de los costes para la salud pública. Una de las soluciones sería recurrir a los servicios de unos intérpretes profesionales. Sin embargo, el hecho de solicitar la participación de dichos profesionales sigue una práctica poco extendida y la razón que se da a menudo es la falta de recursos financieros. ¿Tiene el uso de un intérprete profesional un impacto positivo en la prestación de servicios de salud? ¿Qué tipos de costes supone tal recurso? Para arrojar luz sobre este tema, se llevó a cabo el meta-análisis de 35 estudios científicos realizados en los Estados Unidos que abordan estos temas. La conclusión más destacada es que la gestión médica del alófono se mejora de manera significativa y que los costes incurridos son mínimos en comparación con los beneficios obtenidos.Language barriers can have negative consequences for non-English speaking patients’ health and, what’s more, lead to an increase in costs for public health. One of the solutions would be to use professional interpreters. However, asking for the intervention of these professionals is not common practice yet and the reason often given is the lack of financial resources. Does the use of a professional interpreter positively impact the delivery of health care? What are the costs of such use? In order to shed light on this topic, we proceeded with a meta-analysis of 35 scientific studies conducted in the United States that address these issues. The main result is that the improvement in the medical management of the non-English speaking patient is noticeable and that the costs are minimal compared to the obtained benefits

    Avantages et Coûts du Recours à Un Interprète Professionnel en Milieu Médical : Méta-Analyse de 35 Études Menées aux États-Unis

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    Résumé : Les barrières linguistiques peuvent avoir des conséquences négatives sur la santé des patients allophones et entraîner, de surcroît, une augmentation des coûts pour la santé publique. L’une des solutions serait de faire appel à des interprètes professionnels. Or, demander l’intervention de ces professionnels reste encore une pratique faiblement répandue et la raison souvent invoquée est le manque de moyens financiers. Le recours à un interprète professionnel influence-t-il positivement la trajectoire des soins de santé ? Quels sont les coûts de ce recours ? Pour éclairer cette problématique, nous avons procédé à la méta-analyse de 35 études scientifiques menées sur le sol américain qui abordent ces deux questions. Le résultat principal est que l’amélioration de la prise en charge médicale de l’allophone est sensible et que les coûts engagés sont minimes par rapport au bénéfice retiré.Resumen: Las barreras del idioma pueden tener consecuencias negativas para la salud de los pacientes que no hablan inglés y pueden además traer aparejado un aumento de los costes para la salud pública. Una de las soluciones sería recurrir a los servicios de unos intérpretes profesionales. Sin embargo, el hecho de solicitar la participación de dichos profesionales sigue una práctica poco extendida y la razón que se da a menudo es la falta de recursos financieros. ¿Tiene el uso de un intérprete profesional un impacto positivo en la prestación de servicios de salud? ¿Qué tipos de costes supone tal recurso? Para arrojar luz sobre este tema, se llevó a cabo el meta-análisis de 35 estudios científicos realizados en los Estados Unidos que abordan estos temas. La conclusión más destacada es que la gestión médica del alófono se mejora de manera significativa y que los costes incurridos son mínimos en comparación con los beneficios obtenidos

    Leslie Kaplan: Renverser la norme. A Round Table

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    With Leslie Kaplan (author), Julien Lefort-Favreau (Queens University), Jennifer Pap (University of Denver), Éric Trudel (Bard College), Nathalie Dupont (Bucknell University), Morgane Kieffer (Université Jean Monnet). Recorded on March 12, 2021
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