692 research outputs found
A genome analysis based on repeat sharing gene networks
No full textMotivated by an interest to understand how information is organized within genomes, and how genes communicate between each other in the transcription process, in this paper we propose a novel network based methodology for genomic sequence analysis, specifically applied to three organisms: Nanoarchaeum equitans, Escherichia coli, and Saccaromyces cerevisiae. A dictionary based approach previously introduced is here continued through a repeat analysis in genic and intergenic regions. Key results of this work have been found in a biological and computational analysis of novel parametrized gene networks, defined by means of motifs of fixed length occurring inside multiple genes. Cliques emerge as groups of genes sharing a long repeat with a clear biological interpretation, while a (complete, paralog) cluster analysis has outlined some unexpected regularity. Repeat sharing gene networks may be applied in contexts of comparative genomics, as an investigation methodology for a comprehension of evolutional and functional properties of genes
S-BLOSUM: classification of 2D shapes with biological sequence alignment
No full textRecent works investigated the possibility to design solutions for pattern recognition problems by exploiting the huge amount of work done in bioinformatics. If the pattern recognition problem is cast in biological terms, then a huge range of algorithms, exploitable for classification, detection, visualization, etc. can be effectively borrowed. In this paper, we exploit biological sequence alignment tools to classify 2D shapes, tailoring the biological parameters of these tools to account for the different semantic of the 2D shape scenario. In particular, we propose a novel substitution matrix, which is the crucial parameter determining the sequence alignment solution. The new matrix, called S-BLOSUM, learns the rates of matches/mismatches in conserved portions of shapes belonging to the same category, and incorporates prior knowledge on the chosen representation for the 2D shape. On one hand, the experimental evaluation showed that the S-LOSUM provides a great improvement over the biological counterpart (BLOSUM); on the other hand, classification results prove that our approach is competitive with respect to other methodologies for shape classification found in the recent literature
Indagini su rivestimenti vetrosi di ceramiche catalane bassomedievali da Alghero mediante analisi P-XRF
No full textIndagini su rivestimenti vetrosi di ceramiche Catalane Bassomedievali da Alghero mediante analisi p-XRF
No full textAn Investigation on Genomic Repeats
No full textMotivated by a general interest to understand sequence based signaling in the cell, and in particular how (even distal) genomic strings communicate each other in the transcriptional process, we present a bioinformatic investigation on genomic repeats which occur in multiple genes. Unconventional graph based methods to abstractly represent genomes, gene networks, and genomic languages are provided. In particular, the distribution of long repeats along genomic sequences from three specific organisms (genome of N. equitans, of E. coli, and chromosome IV of S. cerevisiae) is computed, and efficiently visualized along the entire sequences, with the unexpected result to have most of them occurring inside genes
Indagini su rivestimenti vetrosi di ceramiche Catalane Bassomedievali da Alghero mediante analisi p-XRF
No full textPreliminary archaeometric analyses using pXRF of a selection of glazed pottery framents discovered in Sardini
The Pottesman Collection in the British Museum. Early Dynastic and Sargonic administrative texts. With an Appendix on a Palmyrene Inscription
No full textEdizione, trascrizione, traduzione e commento di un frammento di iscrizione palmirena inedita presente nella collezione Pottesman del British Museum (Appendice Agostini).The British Museum houses a small collection of six cuneiform tablets and a Palmyrene dedicatory inscription purchased in 1987 from the private collection of Solomon Pottesman. The aim of the present contribution is to provide a catalog of this lot and an edition of the so far unpublished cuneiform texts. In the appendix, Alessio Agostini added the edition of the Palmyrene inscription, which would have otherwise gone beyond the capabilities of the present author
Recensione di Cecilia Falchini (2023). Ruperto di deutz - Un’intima familiarità. Antologia, Edizioni Qiqajon (Comunità di Bose), Magnano (Bi), 281 pp.
No full textReview of Cecilia Falchini (2023). Ruperto di deutz - Un’intima familiarità. Antologia, Edizioni Qiqajon (Comunità di Bose), Magnano (Bi), 281 pp.
Author: Alessio MagogaRecensione di Cecilia Falchini (2023). Ruperto di deutz - Un’intima familiarità. Antologia, Edizioni Qiqajon (Comunità di Bose), Magnano (Bi), 281 pp.
Autor: Alessio Magog
Optimal management and data-based predictive control of district heating systems: The Novate Milanese experimental case-study
No full textThis paper addresses the modelling and optimal control of district heating systems connected to the electrical grid, with the goal of maximizing their operational efficiency and enabling the participation to electricity markets. Being these systems governed by nonlinear large-scale dynamical models, a novel procedure is proposed, which enables to obtain suitable models for optimization, and consisting in a combination of physical and identified piece-wise linear models. A two-phase optimization and control scheme is then designed, including an offline scheduling problem for participating to the day-ahead energy market, and an online Model Predictive Control system, minimizing the energy consumption of thermal generators while properly satisfying the users thermal demand. The proposed methodology is developed considering a real district heating plant, owned by the energy company A2A S.p.A. and supplying the city of Novate Milanese (Italy), and different experiments on the plant have been carried out. The experimental results and achieved performances are promising, showing a significant reduction of the operational costs and overall gas consumption
Handheld-Impedance-Measurement System with seven-decade capability and potentiostatic function
Full text linkThis paper describes design and test of a new impedance-measurement system for nonlinear devices that exhibits a seven-decade range and works down to a frequency of 0.01 Hz. The system is specifically designed for electrochemical measurements, but the proposed architecture can be employed in many other fields where flexible signal generation and analysis are required. The system employs an unconventional signal generator based on two pulsewidth modulation (PWM) oscillators and an autocalibration system that allows uncertainties of less than 3% to be obtained over a range of 1 kΩ to 100 GΩ. A synchronous demodulation processing allows the noise superimposed to the low-amplitude input signals to be made negligibl
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