20 research outputs found
Early bone loss in 4T1 tumor-bearing mice is T cell mediated and <b>independent of metastatic colonization.</b>
No full text<p>CD3<sup>+</sup> T cells derived from iliac BM of BALB/c mice, 11 days after 4T1 (T 4T1) or 67NR(T 67NR) tumor cells injection into the mammary fat pad, or control T cells from naïve mice (T Nv) were transferred intravenously to athymic nude mice and challenged with the soluble fraction of tumor antigen lysate (sAg). (<b>A</b>) 14 days after transference, spleen cells were restimulated with sAg and IL-17F and RANKL production was evaluated by ELISA. Data are expressed as the mean ± SD of five mice/group and are representative of two independent experiments <sup><i>*</i></sup><i>p≤0.05.</i> (<b>B</b>) Frequency of IL-17F<sup>+</sup> RANKL<sup>+</sup> T cells was assessed by flow cytometry, 14 days after T cells transference. Plots show data from CD3<sup>+</sup> CD4<sup>+</sup> gated T cells. (<b>C</b>) Serum concentrations of OPG and RANKL and the OPG/RANKL ratio, measured by ELISA, 14 days after T cells transference. Data are expressed as the mean ± SD of five mice/group. <i>a, b, c ,d** p<0.001</i>. (<b>D</b>) Histomorphometric analysis of the iliac bones from mice of the different groups and (<b>E</b>) high resolution µCT analysis of the iliac bones. Both analyses were performed as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0068171#pone-0068171-g003" target="_blank">Figure 3</a>. Results shown are representative of at least two independent experiments with 5 mice/group. a, b, c ,d* p<0.05.</p
The operation of ecosystems and game theory. II. Cooperation.
No full textArtykuł nie zawiera streszczeniaThe article contains no abstrac
Campaña de comunicación integral con perspectiva de género sobre las paternidades responsables e igualitarias en la Facultad de Antropología de la Universidad Autónoma del Estado de México
No full textEn la actualidad, de acuerdo a documentos internacionales y nacionales firmados por México1 es imprescindible generar acciones que abonen a la igualdad de género para de esta forma eliminar las desigualdades entre hombres y mujeres, por ello, el presente trabajo aborda las paternidades como un tema prioritario para la participación de los hombres en cuanto a sus derechos sexuales y reproductivos, el embarazo y posparto y la forma de ejercer la paternidad o las paternidades dentro del trabajo doméstico y del trabajo de cuidados no remunerado. El propósito del presente texto es dimensionar con un diagnóstico realizado en la Facultad de Antropología de la Universidad Autónoma del Estado de México (UAEMéx), el ejercicio de la paternidad de los hombres padres académicos, con lo cual se presenta una estrategia de intervención para ese organismo académico. Este texto consta de once apartados que van desde la problematización de género hasta el diseño de la propuesta de intervención. En el primer apartado se presentan las bases conceptuales que permiten el acercamiento a temas como el sexo, género, los roles y estereotipos de género, la división sexual del trabajo, la paternidad tradicional, los tipos de paternidades y la igualdad de género. La construcción de un marco conceptual tiene la intención de comprender los temas que guían a los diagnósticos y a la propuesta final. Posteriormente, se identifica la problemática central de este proyecto, complementándolo con el tema de la licencia de paternidad y se muestra cómo ésta no es garantía para la trasformación de la paternidad tradicional. Después se precisa la justificación, que, a partir de registros diferenciados por sexo, se habla de los temas en donde los hombres no han tenido la misma participación que las mujeres y con ello se denota la desigualdad dentro del ámbito doméstico y dentro del trabajo de cuidados no remunerados
Оцінка вчителями психічного здоров'я дітей з особливими освітніми потребами під час війни
No full textAim: To study the results of teachers’ assessment of the mental health of high schoolers with special educational needs (SEN) after the 1.5 years of war in Ukraine.
Materials and Methods: Teachers’ assessment of the mental health of high schoolers with SEN was conducted through an anonymous survey of teachers using the questionnaire developed by the authors. The research, conducted in 2023, involved 739 teachers working with high schoolers (ages 6-10) with SEN.
Results: It was found that 32.3 % of high schoolers were in the combat zone or on the temporarily occupied territory; 31.7 % of high schoolers were forced to leave their homes and were temporarily displaced, 17.7 % went through a separation from their parents, 15.8 % witnessed hostilities, and 3.8 % suffered bullying from their peers. In the educational process, high schoolers with SEN most often experienced anxiety (55.2 %), “emotional swings” (48.4 %), restlessness (44.8 %), fear (37.2 %). During the 1.5 years of war, 15.4 % of high schoolers began to study worse, 12.9 % began to spend more time playing computer games and on social media. It was found that 59.9 % of teachers need more information on maintaining the mental health of high schoolers with SEN.
Conclusions: The results obtained proved the negative impact of hostilities on the territory of Ukraine on the mental health of high schoolers with SEN, which necessitates the provision of adequate psychological support by teachers of such high schoolers in the educational process.Мета: Дослідити результати оцінки вчителями психічного здоров'я старшокласників з особливими освітніми потребами (ООП) після 1,5 років війни в Україні.
Матеріали та методи: Оцінка вчителями психічного здоров'я старшокласників з SEN проводилася за допомогою анонімного опитування вчителів
за допомогою анкети, розробленої авторами. У дослідженні, проведеному в 2023 році, взяли участь 739 вчителів, які працюють зі старшокласниками (віком 6-10 років) з SEN.
Результати: Було встановлено, що 32,3 % старшокласників перебували в зоні бойових дій або на тимчасово окупованій території; 31,7 % старшокласників були змушені
залишити свої домівки і стали тимчасово переміщеними особами, 17,7 % пережили розлуку з батьками, 15,8 % стали свідками бойових дій, а 3,8 % зазнали
знущань з боку однолітків. У процесі навчання старшокласники з ОНП найчастіше відчували тривогу (55,2 %), «емоційні коливання» (48,4 %), неспокій
(44,8 %), страху (37,2 %). За 1,5 роки війни 15,4 % старшокласників почали гірше вчитися, 12,9 % почали більше часу проводити за комп'ютерними іграми
та в соціальних мережах. Було виявлено, що 59,9 % вчителів потребують більше інформації про збереження психічного здоров'я старшокласників з ОНВ.
Висновки: Отримані результати довели негативний вплив військових дій на території України на психічне здоров'я учнів середніх шкіл з особливими освітніми потребами, що
вимагає надання адекватної психологічної підтримки вчителями таких учнів у процесі навчання
Anticipation mechanism for cold wave: forecast based financing a case study in the Peruvian andes
No full textIn June 2018, the Peruvian provinces of Arequipa and Puno in the southern Andean region were affected by heavy snowfall, which caused severe damage to people and livelihoods in several communities. Using the Forecast-based Financing approach, the Peruvian Red Cross implemented its pre-defined early action protocol before this event, after receiving an extreme snowfall warning (Level 4) from the Peruvian meteorological service. Here, we provide a case study of the approach and event itself, documenting the decision-making thresholds as well as the actions taken. This warning activated
the thresholds established in the protocol, and Peruvian Red Cross prioritized 10 communities for pre-disaster support based on the forecasted severity of the event in combination with vulnerability and exposure information. The activation took place 2 days before the extreme snowfall in the communities, and the Red Cross distributed veterinary kits for 50 heads of cattle per family, tarpaulins, tool kits to install a temporary awning for alpacas to protect them from the cold wind and snow, protection kits for alpaca herders and warm clothing for children under five, pregnant women, the elderly, and people with chronic and infectious diseases in 430 highly vulnerable households. This article presents the results of a household survey following the impact of the extreme snowfall. We document the early actions taken by these communities to protect their livelihoods, health, and assets. The evaluation also presents descriptive statistics of household-level outcomes for households receiving pre-snowfall support and those that did not receive any intervention or only received post-disaster assistance. While most households took
action to protect their assets, there were fewer extreme losses of alpaca herds reported in the communities who received the early support, and these communities also reported fewer adults suffering from respiratory illnesses. More in-depth research on this type of early action is necessary on a wider scale, especially to evaluate the utility of different support measures and the necessary quantity of support needed. This case study can inform government, civil society, and humanitarian actors of how early action is happening before disasters occur and provide a direction for further investment in research and practice to make use of hydro-meteorological forecasts for the benefit of the most vulnerable.Campus Lima Centr
Vanadium Electrolyte Densification and Gel Formation Processes
No full textThis paper describes the processes used to transform
liquid vanadium
electrolytes into solid form for shipment from the manufacturing site
to the vanadium redox flow battery application site. The processes
involve removing a large amount of water from the vanadium electrolytes
by forward osmosis and transforming the concentrated electrolytes
into a low-crystallinity, gel-like solid that can be quickly reconstituted
to its original liquid form by the addition of water. The osmosis
cell consists of two liquid compartments separated by a Nafion 211
membrane supported by a porous carbon layer on each side. Concentrated
sulfuric acid was used as the draw solution and fed in the counterdirection
from the vanadium electrolyte feed. This study identifies the optimal
conditions for full-gel formation, requiring the following: electrolyte
densification level ≥50%, nucleation material density ≥10
mg/mL, and mixing time ≥1 h. The precipitation process was
successfully demonstrated for volumes up to 200 mL. This study also
found that phosphoric acid, often added to improve the stability of
these vanadium sulfate electrolytes, has an adverse impact on the
precipitation process but can be overcome with a higher electrolyte
densification level or higher nucleation material density
Trap set on a brushtail possum trap-line at a sampling location in non-forest habitat.
No full text<p>(Photo: David M. Forsyth.)</p
Effects of reducing sampling effort on estimated brushtail possum occupancy and relative abundance.
No full text<p>(a) Occupancy. (b) Relative abundance (Trap Catch Index). There were 85 sampling locations in forest habitat and 79 sampling locations in non-forest habitat. Vertical bars indicate 95% credible intervals.</p
The brushtail possum was introduced from Australia to New Zealand and is now a major pest.
No full text<p>(Photo: Grant A. Morriss.)</p
