258 research outputs found

    Supplemental_Table1_0928 - Effects of Inotropes on the Mortality in Patients With Septic Shock

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    Supplemental_Table1_0928 for Effects of Inotropes on the Mortality in Patients With Septic Shock by Ryota Sato, Nobuhiro Ariyoshi, Daisuke Hasegawa, Erin Crossey, Natsumi Hamahata, Takuma Ishihara, Michitaka Nasu and Gehan Devendra in Journal of Intensive Care Medicine</p

    Supplemental_Table_2 - Effects of Inotropes on the Mortality in Patients With Septic Shock

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    Supplemental_Table_2 for Effects of Inotropes on the Mortality in Patients With Septic Shock by Ryota Sato, Nobuhiro Ariyoshi, Daisuke Hasegawa, Erin Crossey, Natsumi Hamahata, Takuma Ishihara, Michitaka Nasu and Gehan Devendra in Journal of Intensive Care Medicine</p

    Tehnologizarea învățământului: aspecte actuale și de perspectivă

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    The technical and scientific progress has provided people with devices, machines, technologies and inventions which ease the work and even replace the Man not only in the sphere of production, but also in the sphere of intellectual activity, striving for a longer future, and in some spheres of activity, even in a fairly near future, completely replacing human activity. In his article "Technologization of education: current and long-term aspects", the author tries to partially predict the influence of the technical and scientific progress on education as an important, indispensable sphere of human activity, including the possible changes of the Man under this influence.Nasu, Ilie. Tehnologizarea învățământului: aspecte actuale și de perspectivă / I. Nasu // Tradiţie şi inovare în cercetarea ştiinţifică, Ediţia a 8-a: Materialele Colloquia Professorum din 12 oct. 2018. – Bălţi : US "Alecu Russo", 2019. – P. 185-190. – ISBN 978-9975-50-235

    Fenomenul învăţămîntului finlandez: elementele-cheie.[Articol]

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    In his article "The phenomenon of the Finnish Education – the Key Elements" the author Ilie Nasu describes the basic elements of the educational system in Finland, which according to the international ating is presented as one of the most efficient educational systems in the world For the most part the Finnish school excludes / ignores the traditionalism of the European schools, proposing instead a strictly individualized / differentiated educational process, combined with high of responsibility of the student's teacher for the destiny of the future citizen of the country Paradoxically, the results achieved by the students of the Finnish school seem incredible when one realizes that the evaluation process is practically excluded in the course of the school life; there is only an exam at he age of 16, and even then it is conducted peacefully, without stress and negative emotions ... without sur veillance cameras, checks and enhanced security - which, unfortunately, is practiced in the Republic of Moldova

    Time to re-think the use of dobutamine in sepsis

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    Time to re-think the use of dobutamine in sepsis

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    Abstract Dobutamine is commonly used worldwide and included in the protocol for early goal-directed therapy (EGDT). Since the use of dobutamine in EGDT was reported, it has been considered to be an important component, especially in the treatment of septic patients with myocardial dysfunction. However, it is questionable whether dobutamine improves the mortality of sepsis and septic shock. In three recent randomized controlled trials (ProCESS, ProMISe, and ARISE trials), the frequency of dobutamine use was significantly higher in the EGDT group than in the standard care group, but there were no significant differences in the mortality between the groups. These results suggested that dobutamine use may have been overemphasized despite its insignificant effect on the mortality in septic patients. Further, a propensity score analysis revealed that dobutamine use was associated with higher mortality in patients with septic shock. Although dobutamine leads to an increase in cardiac index, myocardial oxygen demand also increases, thus increasing the risk of myocardial ischemia and tachyarrhythmia. It is well known that the mortality in sepsis complicated with atrial fibrillation (AFib) is worse than that in sepsis without AFib. A propensity score-matched analysis reported that β-blockers were associated with better survival in patients with sepsis complicated with AFib. Further, a randomized controlled trial reported that a short-acting β-blocker improved the survival in patients with septic shock. These studies also indicated the risk of β-stimulation during sepsis. Notably, improvements in surrogate markers, such as CI, do not always indicate improvements in patient-centered outcomes, such as mortality. Conversely, some evidence indicates the worsening of patient-centered outcomes despite improvements in surrogate markers. Thus, available evidence suggests that the benefits of dobutamine in patients with sepsis are unclear, but its use might be harmful rather than beneficial, considering the beneficial effects of β-blockers in sepsis that have been reported in recent clinical studies. From this perspective, we will soon have to rethink regarding dobutamine use in patients with sepsis

    Strategii de perspectivă pentru învăţământul din Republica Moldova [Articol]

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    In his article "Perspective strategies for education in the Republic of Moldova" the author, Ilie Nasu, submits some activity aspects of the educational system in the Republic of Moldova to a critical analysis to a certain extent and provides a series of perspective strategies, which in his opinion can improve the current situation of the education. Some proposals, such as the selection of the minister based on competition and by all means on practical criteria and professionalism in the area of activity and the revision of the educational content, seem to comply with the current requirements of the society towards the sphere of education. Other proposals, like switching to electronic education, online education with regard to district schools are innovative and imply substantial saving of budgetary sources, which nowadays are irresponsibly wasted. The perspective strategies proposed for discussion and implementation are presented as a demand on behalf of the civil society towards the state authorities: the Ministry of Education, the Government and the Parliament, who are responsible of the situation of the education to the society

    Book of abstracts of the 6th International Conference "Fracture Mechanics of Materials and Structural Integrity" (June 3–6, 2019, Lviv, Ukraine)

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    Fracture Mechanics of Materials and Structural Integrity: Book of abstracts of the 6th International Conference (June 3–6, 2019, Lviv, Ukraine) / Edited by V. Panasyuk. Lviv: Karpenko Physico-Mechanical Institute of NASU, 2019. 136 p
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