138 research outputs found

    Introduction to High Performance Computing

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    Author: Henry Neeman, University of Oklahoma Assistant Vice President, Information Technology Research Strategy Advisor Director, OU Supercomputing Center for Education & Research (OSCER) Associate Professor, College of Engineering Adjunct Faculty, School of Computer Science"Introduction to HPC" (Henry Neeman) presented at the Linux Cluster Institute (LCI) Workshop, Mon May 18 2015Linux Cluster Institute The University of Oklahoma The University of Oklahoma Supercomputing Center for Education & Research (OSCER)N

    Does Terrorism Work?

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    This paper examines whether terrorism is an effective tool to achieve political goals. By exploiting variation in terror attacks over time and across locations in Israel from 1984 to 2006, we show that local terror attacks cause Israelis to be: (i) more willing to grant territorial concessions to the Palestinians; (ii) more willing to accept a Palestinian state; (iii) less likely to identify oneself as being right-wing; and (iv) more likely to have a favorable opinion of Arabs. These effects are especially pronounced for individuals from particular demographic groups which are typically right-wing in their political views. In addition, we show that terror induces Israelis to vote increasingly for right-wing parties. This pattern of results demonstrates that right-wing parties are becoming more accommodating to Palestinian demands for territorial concessions. Hence, this paper shows that terrorism appears to be an effective strategy in terms of shifting the entire Israeli political landscape to the left. These findings may shed light on the causes underlying the spread of global terrorism in the last few decades.

    Assessment of Angiogenesis by MRI

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    An example of a non-Fourier-Mukai functor between derived categories of coherent sheaves

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    Orlov’s famous representability theorem asserts that any fully faithful exact functor between the bounded derived categories of coherent sheaves on smooth projective varieties is a Fourier–Mukai functor. In this paper we show that this result is false without the fully faithfulness hypothesis. We also show that our functor does not lift to the homotopy category of spectral categories if the ground field is {\mathbb Q}.This research started at the Mathematical Sciences Research Institute in 2013 with the support of the National Science Foundation under Grant No. 0932078 000. A number of results were obtained during research visits of the first author to the University of Hasselt, supported by ESF Exchange Grant 4498 in the framework of the Project “Interactions of Low-Dimensional Topology and Geometry with Mathematical Physics (ITGP)” and by the FWO Grant 1503512N “Non-commutative algebraic geometry” and by the second author to the International School for Advanced Studies (SISSA) at Trieste. The research by Amnon Neeman was partly supported by the Australian Research Council

    Perspectives: MRI of angiogenesis

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    Dynamic Remodeling of the Vascular Bed Precedes Tumor Growth: MLS Ovarian Carcinoma Spheroids Implanted in Nude Mice

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    AbstractThe goal of this study was to monitor the vascular bed during the lag phase in growth of implanted spheroids as a model of tumor dormancy. Vascular development and tumor growth were followed up by magnetic resonance imaging in a model system of MILS ovarian carcinoma spheroids implanted subcutaneously in female nude mice. Apparent vessel density in a 1-mm rim surrounding the spheroid was evaluated by gradient echo imaging as a measure of the angiogenic potential of the tumor. Vascular functionality and maturation were assessed by signal intensity changes in response to hyperoxia (elevated oxygen) and hypercapnia (elevated carbon dioxide), respectively. Tumor growth was delayed by 12 to 57 days after implantation. During this long period in which tumor volume did not change, up to 6 cycles of vascular development and regression were observed. We propose here that dynamic remodeling of the vascular bed may precede exit of tumors from dormancy. The sustained oscillations in the angiogenic response to the implanted spheroid are consistent with hypoxic regulation of vascular endothelial growth factor (VEGF), combined with the role of VEGF as an essential survival factor for newly formed blood vessels. Vascular maturation, manifested by physiological vasodilatory response to carbon dioxide, may be important for conferring vascular stability and exit from dormancy
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