1,013 research outputs found
Patterns of regional brain hypometabolism associated with knowledge of semantic features and categories in Alzheimer's disease
No full textThe study of semantic memory in patients with Alzheimer's disease (AD) has raised important questions about the representation of conceptual knowledge in the human brain. It is still unknown whether semantic memory impairments are caused by localized damage to specialized regions or by diffuse damage to distributed representations within nonspecialized brain areas. To our knowledge, there have been no direct correlations of neuroimaging of in vivo brain function in AD with performance on tasks differentially addressing visual and functional knowledge of living and nonliving concepts. We used a semantic verification task and resting 18-fluorodeoxyglucose positron emission tomography in a group of mild to moderate AD patients to investigate this issue. The four task conditions required semantic knowledge of (1) visual, (2) functional properties of living objects, and (3) visual or (4) functional properties of nonliving objects. Visual property verification of living objects was significantly correlated with left posterior fusiform gyrus metabolism (Brodmann's area [BA] 37/19). Effects of visual and functional property verification for nonliving objects largely overlapped in the left anterior temporal (BA 38/20) and bilateral premotor areas (BA 6), with the visual condition extending more into left lateral precentral areas. There were no associations with functional property verification for living concepts. Our results provide strong support for anatomically separable representations of living and nonliving concepts, as well as visual feature knowledge of living objects, and against distributed accounts of semantic memory that view visual and functional features of living and nonliving objects as distributed across a common set of brain area
On-chip Microdialysis System with Flow-through Glucose Sensing Capabilities
No full textThe published version of this article is available at http://www.journalofdst.org/May2007/pdf/VOL-1-3-ORG3-HSIEH.pd
Non-Invasive Glucose Monitoring: A Novel Approach
No full textBackground: The main concern in noninvasive (NI) glucose measurement is achieving high accuracy readings, although no blood (or other fluid) is involved in the process. Using methods based on different physical properties of a measured object can ensure the independence of each of the readings and therefore improve the validity of the end result. By using a combination of (three) independent technologies—ultrasonic, electromagnetic, and thermal—GlucoTrack™ presents a unique approach for a real-time, truly NI blood glucose spot measurement. Methods: Clinical trials were performed in two stages. Stage 1 was an initial method validation and performance verification of the device. In this stage, 50 type 1 and 2 diabetic patients, as well as healthy subjects, were evaluated with GlucoTrack against Ascensia Elite® (Bayer). In the second stage, 85 additional diabetic subjects were evaluated in half and full daytime sessions using a GlucoTrack comparison with HemoCue® (Glucose 201+). Results: A total of 135 subjects were tested during the trial period, producing 793 data pairs. Using Clarke error grid analysis, 92% of the readings fell in the clinically acceptable zones A and B, with 50% in the A zone. Mean and median relative absolute differences were 29.9 and 19.9%, respectively. Conclusions: Integrating several modalities for NI assessment of glucose level enables more accurate readings, while a possible aberration in one modality is bypassed by the others. The present generation of GlucoTrack gives promising results; however, further improvement of the accuracy of the device is needed.The published version of this article is available at http://www.journalofdst.org/amember/plugins/protect/new_rewrite/login.php?v=-any&url=/March2009/Articles/VOL-3-2-SYM4-HARMAN-BOEHM.pdf%3
Erbauliche Gedancken über den Gottes-Acker vor Halle Wie solche Bey hochansehnlicher Beerdigung Der Hoch-Edlen und Hoch-Tugendbelobten Frauen, Fr. Dorotheen Sophien, gebohrner Strauchin, Des ... Friedrich Hohndorffs, Hochberühmter Jc. ... Hoff- und Regierungs-Rath im Hertzogthum Magdeburg, wie auch Saltz-Gräfe allhier. Nachgelassener Frau Wittwe Den 27. Januarii 1710. in einer Abdanckung ... Vorgetragen Io. Mich. Heineccius, Der Heil. Schrifft D. Königl. Preußischer Consistorial-Rath im Hertzogthum Magdeburg und Inspector des hiesigen Stadt-Ministerii, wie auch der Kirchen und Schulen im Saal-Creyß, Ober-Pfarrer und Pastor zu U. L. Frauen, und des Gymnasii Scholarcha
No full textVorlageform des Erscheinungsvermerks: Halle, gedruckt bey Joh. Christian Zahn, Univ. u. E. E. Raths-Buchdr
Die Missionskonzeption Franz Michael Zahns (1862-1900) : Überlegungen zur epistemischen Dimension der kolonialen Begegnungen in Togo
No full textAn epistemology of colonialism using the example of the mission concept of the NMG mission inspector Franz Michael Zahn, who died in 1900. The author analyses the effects of missionary work in South Togo and refers to the discourse theory of Michael Foucault. In the dissertation, the investigation of colonial power takes the form of a moral-critical analysis with a focus on the concept of "colonial ethics". The author summarized missionary or colonial knowledge understood as knowledge of (Christian) governmental practice (colonial governmentality) with the concept of morality and, for colonial historiography, shapes the new object of analysis of the "moral discourse".
Eine Epistemologie des Kolonialismus am Beispiel der Missionskonzeption von dem im Jahre 1900 verstorbenen Missionsinspektor der NMG Franz Michael Zahn. Der Autor analysiert die Auswirkungen der Missionierung im Süd-Togo und bezieht sich dabei auf die Diskurstheorie von Michael Foucault. Die Untersuchung der Kolonialmacht nimmt in der Dissertation die Form einer moralkritischen Analyse mit Fokus auf den Begriff der "Kolonialethik". Das Missions-bzw. Kolonialwissen verstanden als ein Wissen der (christlichen) Regierungspraxis (koloniale Gouvernementalität) fasste der Autor mit dem Moralbegriff zusammen und prägt für die Kolonialgeschichtschreibung den neuen Analysegegenstand des "Moraldiskurses"
Hieracium murorum subsp. cophogonium Bornm. & Zahn
No full textHieracium murorum subsp. cophogonium Bornm. & Zahn in Zahn (1925: 161). Ind. loc.: “Frontière bâloise-badoise: Hohr[sic!] M i hr près Zell (A. Krafft). Trouvé aussi par Bornmüller à Tr i bsdorf, près Weimar, dans la Thuringe.” Lectotype (designated here by Gottschlich): — GERMANY. Baden-Wuerttemberg: Hohe M i hr, 11 June 1923, A. Krafft (BREG!). — Remaining syntype: GERMANY. Thuringia: Weimar, Tr i bsdorf, westl. bei d. Bahnbrücke, 8 June 1923, J. Bornmüller (B barcode B 10 0460350!). Remarks: —Although Bornmüller is co-author of the taxon, in the protologue the collection of Krafft is cited first and is here selected as lectotype.Published as part of Vogt, Robert & Gottschlich, Günter, 2023, Type material in the Hieracium (Compositae: Cichorieae) collection of Joseph Bornmüller, pp. 81-126 in Phytotaxa 613 (2) on page 102, DOI: 10.11646/phytotaxa.613.2.1, http://zenodo.org/record/834553
Use of controlled release opioids in perioperative pain therapy - A standpoint on a new warning advice in literature on controlled release opioids
No full textEuropean enlargement and the economic crisis : impact and lasting effects
No full textThis working paper by Rebecca Zahn looks at the effects of the economic crisis on the enlarged European Union and the European Social Model. Starting from an analysis of the well-known Viking and Laval decisions of the European Court of Justice from 2007 and 2008, the author of the report sees increasing tensions between EU member states over “social dumping”, austerity packages and growing inequality between workers. This development results in citizens questioning the benefits of further European integration and threatens the very existence of the European social model
Three hundred eighty thousand year long stable isotope and faunal records from the Red Sea : influence of global sea level change on hydrography
No full textStable isotope and faunal records from the central Red Sea show high-amplitude oscillations for the past 380,000 years. Positive δ18O anomalies indicate periods of significant salt buildup during periods of lowered sea level when water mass exchange with the Arabian Sea was reduced due to a reduced geometry of the Bab el Mandeb Strait. Salinities as high as 53‰ and 55‰ are inferred from pteropod and benthic foraminifera δ18O, respectively, for the last glacial maximum. During this period all planktonic foraminifera vanished from this part of the Red Sea. Environmental conditions improved rapidly after 13 ka as salinities decreased due to rising sea level. The foraminiferal fauna started to reappear and was fully reestablished between 9 ka and 8 ka. Spectral analysis of the planktonic δ18O record documents highest variance in the orbital eccentricity, obliquity, and precession bands, indicating a dominant influence of climatically - driven sea level change on environmental conditions in the Red Sea. Variance in the precession band is enhanced compared to the global mean marine climate record (SPECMAP), suggesting an additional influence of the Indian monsoon system on Red Sea climates
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