3,156 research outputs found

    Vaccine prevention of virus-induced human cancers: 1986 Florey Lecture presented by Professor Anthony Epstein at the Australian National University

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    Professor Epstein discusses his current work towards developing a subunit vaccine for Epstein-Barr virus. -- Recorded at Leonard Huxley Theatre, 15 August 1986

    Diphoton decay of the higgs from the Epstein–Glaser viewpoint

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    We revisit a nearly 10-year old controversy on the diphoton decay of the Higgs particle. To a large extent, the controversy turned around the respective merits of the regularization techniques employed. The novel aspect of our approach is that no regularization techniques are brought to bear: we work within the Bogoliubov–Epstein–Glaser scheme of renormalization by extension of distributions. Solving the problem actually required an expansion of this method’s toolkit, furnished in the paper

    Is a Manuscript a Mirror? Reading Jewish History in Jewish Art

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    2018 Adolph and Ruth Schnurmacher Lecture in Judaic Studies. [Speaker] Marc Michael Epstein, PhD. Professor of Religion and Visual Culture, Vassar College.https://digitalcommons.fairfield.edu/bennettcenter-posters/1348/thumbnail.jp

    The influence of African sculpture on British art, 1910-1930

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    This thesis aims to discuss the influence of African wood sculpture on British art from 1910 to 1930. It proposes that the works, tastes and pronouncements of various 20th century British artists betray this influence and that although the British artists did not initially understand the conceptual foundations of African sculpture their limited knowledge was just sufficient for the modernization of British art through the adaptation of the formal qualities of African art. In assessing the validity of these propositions the thesis examines the factors and issues that facilitated the influence. Chapter 1 discusses the formal qualities of African wood sculpture that attracted the British artists. It outlines the unusual figural proportions, the free and direct use of planar, linear and solid geometry, the treatment of material and its surfaces. The conceptual foundations of African sculpture are generally outlined in Chapter 2. The extent to which the British artists understood these foundations is also discussed. Chapter 3 concerns the introduction of African sculpture to Britain and discusses the development of the anthropological and subsequent aesthetic interest that it aroused. Both the Post-Impressionist Exhibitions and the Omega Workshops which facilitated its influence are examined. Chapter 4 examines the concept and attempts to categorize the nature of this influence. The last three chapters act as case studies in which the impact of African sculpture on Epstein, Gaudier-Brzeska and Henry Moore is examined. The conclusion discusses the term 'Primitive' and the British artists and the 'Primitive

    Good Without God: What a Billion Nonreligious People Do Believe

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    Author Greg Epstein, the Humanist chaplain at Harvard, offers a world view for nonbelievers that dispenses with the hostility and intolerance of religion prevalent in national bestsellers like God is Not Great and The God Delusion. Epstein\u27s Good Without God provides a constructive, challenging response to these manifestos by getting to the heart of Humanism and its positive belief in tolerance, community, morality, and good without having to rely on the guidance of a higher being.--From publisher description.https://scholar.dominican.edu/cynthia-stokes-brown-books-big-history/1099/thumbnail.jp

    Who owns native nature? Discourses of rights to land, culture, and knowledge in New Zealand

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    Michael Brown famously asked ‘Who owns native culture?’ This paper revisits that question by analyzing what happens to culture when the culturally defined boundary between it and nature becomes salient in the context of disputes between indigenous and settler populations. My case study is the dispute between the New Zealand government and Maori tribal groupings concerning ownership of the foreshore and seabed. Having been granted the right to test their claims in court in 2003, Maori groups were enraged when the government legislated the right out of existence in 2004. Though the reasons for doing so were clearly political, contrasting cultural assumptions appeared to set Maori and Pakeha (New Zealanders of European origin) at odds. While couching ownership of part of nature as an IPR issue may seem counter-intuitive, I argue that as soon as a property claim destabilizes the nature/culture boundary, IPR discourse becomes pertinent

    Employment-Oriented Central Bank Policy in an Integrated World Economy: A Reform Proposal for South Africa

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    The South African Reserve Bank and Ministry of Finance have adopted inflation targeting and the gradual relaxation of exchange controls (along with control of public spending and financial liberalization) as the foundation of their economic policy in an attempt to win the confidence of foreign investors and to attract more foreign investment. However, this policy has not succeded in generating employment growth or investment. Instead, it has contributed to high real interest rates and relative stagnation.In order to improve central bank and capital management policies and have them contribute more to solving the fundamental problems of unemployment and poverty facing the South African economy, three reforms should be undertaken:1) The Reserve Bank should scrap its inflation targeting approach and adopt a more even handed approach which would target employment growth subject to an inflation constraint.2) Rather than loosening the exchange controls system, the Reserve Bank and Ministry of Finance should enforcethe existing controls more strictly, and explore other ways, such as transaction taxes and speed-bumps, to further insulate South African macroeconomic policy from global pressures.3) The South African government should implement other policies and institutions, such as special lending windows, underwriting facilities, asset based reserve requirements and subsidized credit, to further insulate the South African financial markets from the international capital markets and channel credit to employment generating and socially productive activities. This will correct a serious market failure in which international financial markets fail to take into account the social rates of return available on productive investments in South Africa.

    Conditional immortalization of human B cells by CD40 ligation

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    It is generally assumed that human differentiated cells have a limited life-span and proliferation capacity in vivo, and that genetic modifications are a prerequisite for their immortalization in vitro. Here we readdress this issue, studying the long-term proliferation potential of human B cells. It was shown earlier that human B cells from peripheral blood of healthy donors can be efficiently induced to proliferate for up to ten weeks in vitro by stimulating their receptor CD40 in the presence of interleukin-4. When we applied the same stimuli under conditions of modified cell number and culture size, we were surprised to find that our treatment induced B cells to proliferate throughout an observation period of presently up to 1650 days, representing more than 370 population doublings, which suggested that these B cells were immortalized in vitro. Long-term CD40-stimulated B cell cultures could be established from most healthy adult human donors. These B cells had a constant phenotype, were free from Epstein-Barr virus, and remained dependent on CD40 ligation. They had constitutive telomerase activity and stabilized telomere length. Moreover, they were susceptible to activation by Toll-like receptor 9 ligands, and could be used to expand antigen-specific cytotoxic T cells in vitro. Our results indicate that human somatic cells can evade senescence and be conditionally immortalized by external stimulation only, without a requirement for genetic manipulation or oncoviral infection. Conditionally immortalized human B cells are a new tool for immunotherapy and studies of B cell oncogenesis, activation, and function

    Rethinking Monetary and Financial Policy: Practical suggestions for monitoring financial stability while generating employment and poverty reduction

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    As the world financial crisis deepens, the task of generating decent employment has taken on more urgency, yet now faces even more obstacles then before. Of course, a key component of the solution to the current crisis will be massive expansionary fiscal actions on the part of the rich countries, preferably in a coordinated fashion, but individually if necessary. More aid and support from the rich countries and international institutions to the developing world will also be necessary to avoid a very serious, negative shock for the world's poorest and most vulnerable. In the short and medium run, as before the recent crisis, the key will be to generate large scale increases in decent work if developing countries and the world are to avoid a downward spiral into depression. But what macroeconomic policy frameworks should be used to design policies to address this crises both in the short and in the medium terms? � What is clear is that to design and carry out these employment-oriented macroeconomic policies, the old neo-libereal orthodoxy must be abandoned, and policy makers must look for other policy frameworks to inform their macroeconomic and financial policies. � In this paper, Epstein summarize employment oriented macroeconomic and financial policies that governments in developing countries can adopt to help promote more and better employment as a key to reducing poverty over the medium to long run.

    Computation of core losses in electrical machines using improved models for laminated steel

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    Two new models for specific power losses in cold-rolled motor lamination steel are described together with procedures for coefficient identification from standard multifrequency Epstein or single sheet tests. The eddy-current and hysteresis loss coefficients of the improved models are dependent on induction (flux density) and/or frequency, and the errors are substantially lower than those of conventional models over a very wide range of sinusoidal excitation, from 20 Hz to 2 kHz and from 0.05 up to 2 T. The model that considers the coefficients to be variable, with the exception of the hysteresis loss power coefficient that has a constant value of 2, is superior in terms of applicability and phenomenological support. Also included are a comparative study of the material models on three samples of typical steel, mathematical formulations for the extension from the frequency to the time domain, and examples of validation from electrical machine studies
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