672 research outputs found
Percutaneous Coronary Interventions for the Treatment of Stenoses in Small Coronary Arteries: A Network Meta-Analysis.
No full textOBJECTIVES
This study evaluated the most appropriate percutaneous coronary intervention (PCI) for the treatment of stenoses in small coronary arteries.
BACKGROUND
PCI in small coronary arteries is associated with an increased risk of lesion failure and restenosis.
METHODS
Randomized trials comparing different PCI strategies were identified through a broad search of published reports. Primary angiographic outcome was %DS (%DS). A pairwise meta-analysis was performed by using random effects model, followed by a network meta-analysis synthesizing direct and indirect evidence.
RESULTS
Overall, 19 trials were eligible, which included 5,072 patients comprising a network without closed loops among 5 identified interventions (early generation sirolimus-eluting stents [SES], paclitaxel-eluting stents [PES], drug-coated balloons [DCB], bare-metal stents [BMS], and balloon angioplasty [BA]). No dedicated trial was identified evaluating new generation drug-eluting stents. Early generation SES yielded the best angiographic results according to %DS. For %DS, SES was ranked as the most effective treatment, followed by PES (standardized mean differences [SMD]: -0.44; 95% confidence interval [CI]: -0.92 to 0.05 vs. SES) and DCB (SMD: -0.89; 95% CI: -1.53 to -0.25 vs. SES). In terms of absolute differences, SES yielded a reduction of 18% in diameter stenosis compared to DCB. SES significantly reduced the risk of target-lesion revascularization compared to PES (odds ratio [OR]: 0.39; 95% CI: 0.16 to 0.93), DCB (OR: 0.34; 95% CI: 0.10 to 0.97), BMS (OR: 0.21; 95% CI: 0.13 to 0.36), and BA (OR: 0.16; 95% CI: 0.09 to 0.29).
CONCLUSIONS
Early generation SES yielded the most favorable angiographic and clinical outcomes for the treatment of stenoses in small coronary arteries. New generation DES need to be evaluated against this standard in future randomized trials
Entretien de Auréane Lhuissier et Pierre-Fabien Benoit
No full textEnregistrement issu du Corpus de Français Parlé Parisien des années 2000 (CFPP2000
Entretien de Auréane Lhuissier et Pierre-Fabien Benoit
No full textEnregistrement issu du Corpus de Français Parlé Parisien des années 2000 (CFPP2000
Contrasting Compile-Time Meta-Programming in Metalua and Converge
No full textPowerful, safe macro systems allow programs to be programatically constructed by the user at compile-time. Such systems have traditionally been largely confined to LISP-like languages and their successors.
In this paper we describe and compare two modern, dynamically typed languages Converge and Metalua, which both have macro-like systems. We show how, in different ways, they build upon traditional macro systems to explore new ways of constructing programs
Vicarious Dissonance : Meta-analysis
No full textVicarious dissonance is the phenomenon that describes the possibility that individuals may experience cognitive dissonance vicariously when they witness an inconsistent act committed by a member of their own group. After more than 15 years of research, uncertainties remain as to the effectiveness of experimental procedures set up in vicarious dissonance to obtain effects, raising the need for a meta-analytic summary of the literature. In this registered report, we conducted a meta-analysis (k = [X], n = [X]) of the effect of vicarious dissonance. We found [empirical support] for the vicarious dissonance effect, [g = X]. Vicarious dissonance is a meaningful effect for [X]. Study heterogeneity was [Low/high]. [Summarize results]. We tested [List of moderators]. We found that [meaningful moderation] moderated vicarious dissonance. Vicarious dissonance was stronger [list of conditions]. [Brief descriptions of strengths and limitations, and future research directions] We registered our meta-analysis here: https://osf.io/t5vs7/?view_only=e9dc20e90a584afbb2456aecd8809c9
Imaging-Based, Patient-Specific Three-Dimensional Printing to Plan, Train, and Guide Cardiovascular Interventions: A Systematic Review and Meta-Analysis.
No full textBACKGROUND
To tailor cardiovascular interventions, the use of three-dimensional (3D), patient-specific phantoms (3DPSP) encompasses patient education, training, simulation, procedure planning, and outcome-prediction.
AIM
This systematic review and meta-analysis aims to investigate the current and future perspective of 3D printing for cardiovascular interventions.
METHODS
We systematically screened articles on Medline and EMBASE reporting the prospective use of 3DPSP in cardiovascular interventions by using combined search terms. Studies that compared intervention time depending on 3DPSP utilisation were included into a meta-analysis.
RESULTS
We identified 107 studies that prospectively investigated a total of 814 3DPSP in cardiovascular interventions. Most common settings were congenital heart disease (CHD) (38 articles, 6 comparative studies), left atrial appendage (LAA) occlusion (11 articles, 5 comparative, 1 randomised controlled trial [RCT]), and aortic disease (10 articles). All authors described 3DPSP as helpful in assessing complex anatomic conditions, whereas poor tissue mimicry and the non-consideration of physiological properties were cited as limitations. Compared to controls, meta-analysis of six studies showed a significant reduction of intervention time in LAA occlusion (n=3 studies), and surgery due to CHD (n=3) if 3DPSPs were used (Cohen's d=0.54; 95% confidence interval, 0.13 to 0.95; p=0.001), however heterogeneity across studies should be taken into account.
CONCLUSIONS
3DPSP are helpful to plan, train, and guide interventions in patients with complex cardiovascular anatomy. Benefits for patients include reduced intervention time with the potential for lower radiation exposure and shorter mechanical ventilation times. More evidence and RCTs including clinical endpoints are needed to warrant adoption of 3DPSP into routine clinical practice
particleShear: Discrete Python particle simulation with digital rheology and stress tensor evaluation
No full textparticleShear: Python package for particle shear simulation
This package provides a discrete particle simulation kit for having multiple spheres interacting. The spheres (i.e. 2D circles) interact by mutual elastic repulsion and tangential friction upon contact, but can also be crosslinked together. In addition to the elementary implementation of the interacting particles, it is also possible to define rheological experiments where the spheres are exposed to sinusoidally varying displacement conditions on the boundaries. We paid particular attention to avoid pitfalls that generate asymmetric stress tensors.
Acknowledgement: Thanks from the author go to Fabien Bonini and Joé Brefie-Guth for package testing, and to Daniel Lyobenov for initial help with simulation setup.
This repository archives the releases of the source code hosted at https://github.com/tbgitoo/particleShear. The package is available through the Python package server (see https://pypi.org/project/particleShear/1.0.2/). It can be installed automatically in python via
pip3 install particleShear
In some installations, the command may also be pip install particleShear; the minimal version of Python is 3.
Nouvelles données sur la vanuralite. Existence de la méta˗vanuralite
No full textA detailed study of vanuralite has shown that a less hydrated form exists, meta-vanuralite, the transformation from one to the other being reversibly dependent on the humidity of the atmosphere.
Vanuralite Al (UO₂)₂ (VO₄)₂ (OH) . 11H₂O is monoclinic A2/a with a = 10.55 Å, b = 8.44 Å, c = 24.52 Å and β = 103° and with Z = 4. The main powder lines with indices are 11.98 (vvs) 002, 5.98 (vs) 004, 3.795 (s) 006-022, 3.231 (s) 31[-1], 3.180 Å (s) 31[-3]. A twin by pseudosymmetry exists with composition plane (001).
Meta-vanuralite Al (UO₂)₂ (VO₄)₂ (OH).8H₂O is triclinic with a = 10.46 Å, b = 8.44 Å, c = 10.43 Å, α = 75° 53', β = 102° 50', γ = 90° and with Z = 2. The main powder lines with indices are 9.02 (vvs) 001, 4.174 (vs) 021, 4.086 (s) 020-102, 3.240 (s) [-3]11, 3.155 (vs) 221-311, 3,073 Å (s) 3[-1]0-22[-1].
The transition from a monoclinic to a triclinic cell occurs by reduction of the distance between the perfect (001) cleavage planes and slip parallel to the 6-axis.
Meta-vanuralite (8H₂O) is stable at 20° C in an atmosphere of relative humidity between 47 and 28 %.L'étude détaillée de la vanuralite a montré qu'il existait une forme moins hydratée, la méta-vanuralite, le passage de l'une à l'autre étant réversible et dépendant du degré hygrométrique de l'atmosphère.
La vanuralite Al (UO₂)₂ (VO₄)₂ (OH) . 11H₂O est monoclinique A2/a avec les paramètres a = 10,55 Å, b = 8,44 Å, c = 24,52 Å and β = 103° et Z = 4. Les raies principales du diagramme de poudre indexé sont : 11,98 (FFF) 002, 5,98 (FF) 004, 3,975 (F) 006-022, 3,231 (F) 31[-1], 3,180 (F) 31[-3]. Il existe une macle par pseudo-symétrie avec accolement suivant (001).
La méta-vanuralite Al (UO₂)₂ (VO₄)₂ (OH) . 8H₂O est triclinique avec a = 10,46 Å, b = 8,44 Å, c = 10,43 Å, α = 75° 53', β = 102° 50', γ = 90° et Z = 2. Les raies principales du diagramme de poudre indexé sont : 9,92 (FFF), 001, 4,174 (FF), 021, 4,086 (F) 020-102, 3,240 (F) [-3]11, 3,155 (FF) 221-31[-1], 3,073 (F) 3[-1]0-22[-1].
Le passage de la maille monoclinique à la maille triclinique s'effectue par diminution de la distance entre les plans (001) (clivage parfait) et glissement parallèlement au paramètre b.
La méta-vanuralite est stable (8H₂O) à 20° C dans une atmosphère dont le degré d'humidité relative est compris entre 47 et 28 %.Cesbron Fabien. Nouvelles données sur la vanuralite. Existence de la méta˗vanuralite. In: Bulletin de la Société française de Minéralogie et de Cristallographie, volume 93, 2, 1970. pp. 242-248
Optimizing construction of scheduled data flow graph for on-line testability
No full textThe objective of this work is to develop a new methodology for behavioural synthesis using a flow of synthesis, better suited to the scheduling of independent calculations and non-concurrent online testing. The traditional behavioural synthesis process can be defined as the compilation of an algorithmic specification into an architecture composed of a data path and a controller. This stream of synthesis generally involves scheduling, resource allocation, generation of the data path and controller synthesis. Experiments showed that optimization started at the high level synthesis improves the performance of the result, yet the current tools do not offer synthesis optimizations that from the RTL level. This justifies the development of an optimization methodology which takes effect from the behavioural specification and accompanying the synthesis process in its various stages. In this paper we propose the use of algebraic properties (commutativity, associativity and distributivity) to transform readable mathematical formulas of algorithmic specifications into mathematical formulas evaluated efficiently. This will effectively reduce the execution time of scheduling calculations and increase the possibilities of testability
Meta-analysis of the standardized area under the ROC curves (AUROC) assessed in published studies of Fibrotest diagnostic value
No full text<p><b>Copyright information:</b></p><p>Taken from "Meta-analyses of FibroTest diagnostic value in chronic liver disease"</p><p>http://www.biomedcentral.com/1471-230X/7/40</p><p>BMC Gastroenterology 2007;7():40-40.</p><p>Published online 15 Oct 2007</p><p>PMCID:PMC2175505.</p><p></p> There was no significant difference between the different liver diseases
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