1,721,098 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Topical application of isosorbide dinitrate in patients with persistent constipation after pull-throught surgery for Hirschsprung's disease
No full textAims: The aim of this study was to evaluate the anal manometric changes and the clinical effects after topical application of isosorbide dinitrate (ISDN) in patients with persistent constipation after pull-through surgery for Hirschsprung's disease (HD). Methods: We studied 3 children (2 males and 1 female), aged 2, 3 and 5 years respectively, who had undergone the Soave-Boley surgical procedure for HD and who suffered from persistent constipation after operation. We performed a pre- and postoperative anorectal manometry study and we applied ISDN paste (1 mg/kg two times daily) in the anal region for three weeks. All patients were followed-up and re-evaluated at 1,3, and 6 months. Results: All patients showed an improvement of symptoms, with an average of 4 spontaneous evacuations per week. Prior to the topical treatment, the medium pressure was 115.6 mmHg (range 102-130 mmHg), the maximum pressure was 160 mmHg (range 145-175 mmHg), and the medium length of the high pressure zone was 1.8cm (range 1.5-2.0 cm). At the 6 month follow-up, the medium pressure was 57.3 mmHg (range 52-61 mmHg, a decrease of 54.4%), the maximum pressure was 98 mmHg (range 88-107 mmHg; a decrease of 38.7%), and the medium length of the high pressure zone was 1.6 cm (range 1.4-1.8 cm; a decrease of 11.1 %). Conclusions: Topical treatment with ISDN is a valid therapeutic alternative to an anal myotomy in patients with persistent constipation after pull-through surgery for HD. However, a greater number of cases and a longer follow-up are necessary to confirm the validity of our experience. © Georg Thieme Verlag KG Stuttgart New York
Enterocolite da malattia di Hirschsprung: due case report
No full textEnterocolitis is a serious complication of Hirschsprung's disease. The high-risk onset periods are before diagnosis of Hirschsprung's disease and after pull-through operation, but it can
occur in every moment during the clinical history of the affection. Enterocolitis is characterized by the presence of fever, abdominal distension and explosive diarrhea. It is a lifethreatening
disease which treatment is based on electrolytes and water restoration, antibiotic support, total parenteral nutrition and intestinal surgical decompression obtained by colostomy.
However the best treatment is an early diagnosis that is based on the suspect of the disease from the symptoms. The Authors report on 2 babies (respectively lO and 5 months old) with an
acute abdomen that were urgently submitted to surgery which confirmed the clinical diagnosis of enterocolitis. The first baby was affected by Down's syndrome and persistent constipation
since birth, the second one had an history of constipation, short growth and a previous hospitalization for gastroenteritis. Both babies were submitted to surgical decompression by
colostomy before the following operations for the correction of the main affection (Soave-Boyle pull-through) and for the recanalization
Transumbilical Laparoscopic-Assisted Appendicectomy:una valida e sicura alternativa in caso di appendiciti non complicate
No full textL'appendicectomia rappresenta l'intervento chirurgico più comune nel mondo: nel contesto delle emergenze addominali
pediatriche, l'appendicite acuta ricopre il primo posto sia in termini di frequenza di comparsa che di potenziale gravità del quadro clinico. Lo scopo dello studio è quello di valutare le indicazioni, i tempi chirurgici, le complicanze postoperatorie e i risultati estetici della TULAA (Transumbilical Laparoscopic-Assisted Appendicectomy),
tecnica che prevede una appendìcectomia transombelicale
con l'ausilio di un solo trocar. Presso la Sezione di Chirurgia Pediatrica del Dipartimento di Pediatria Ostetricia e Medicina della Riproduzione dell'Università degli Studi di Siena a partire dal Gennaio 2001 sono stati effettuati 50 interventi di appendicectomìa transornbelicale video-assistita (TULAA). L'età media è stata di 9
anni (range 6-18 anni). Il rapporto maschi:femmine è
stato di circa 1:3 (15 maschi: 35 femmine). I pazienti trattati
con TULAA sono stati selezionati in base alla storia
clinica; l'età non è stato un criterio considerato per la
selezione. T candidati all'intervento di TULAA sono stati
tutti quei bambini con una storia di dolori addominali
ricorrenti con sintomatologia algica prevalentemente a
livello della fossa iliaca destra. Inoltre sono stati sottoposti
a tale intervento tutti quei pazienti con risentimento
appendicolare, senza i segni clinici di una peritonite in
atto ed i pazienti obesi. Nella nostra casistica il tasso di
conversione a tecnica vls con trocar aggiuntivi è del
16,8% (8 casi su 50), mentre il tasso di complicanze
postoperatorie è paragona bile a quello riscontrato per
l'appendicectomia vls con tre trocar. In conclusione si
può affermare che la TULAA è una tecnica mininvasiva
realìzzabile in totale sicurezza nei casi di appendicite
acuta non perforata, non complicata o nei casi di DAR da
appendicite malformata, in tempi brevi (15 min circa) e
con eccellenti risultati estetici
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