115,569 research outputs found
MES-Systems - Tips for use and selection
No full text5 S.Der zunehmende Wettbewerbsdruck erfordert die konsequente Erschließung von Optimierungspotentialen im Bereich der kurzfristigen Fertigungsplanung und -steuerung. Hier stößt ERP-Software an Grenzen, da diese das zentrale Informationsrückgrat der unternehmensweiten Kommunikation bildet. Für diesen Anwendungsfall dient MES-Software, die die Aufgaben des Shop Floor unterstützt. Hierzu übernehmen MES-Systeme Datenmanagement-, Entscheidungs- sowie Dokumentations- und Auswertefunktionen. Der Beitrag diskutiert Einsatzkriterien und Notwendigkeit von MES-Software und gibt einen Überblick über die am Markt angebotenen Softwarelösungen
Weldon, Mes. H. B.
No full textPhotograph from the C.R. Savage Portrait Studio. Name associated with the photograph: Mes. H. B. Weldo
The potential of shop-floor planning and control. MES the unfamiliar buzzword?! - Results of a survey
No full textS.65-80Der Begriff MES gewinnt in der Fachpresse und bei den Anwendern zunehmende Beachtung. Somit stellt sich die Frage, wo das Thema heute in der Industrie steht. Hierzu hat das Fraunhofer IPA gemeinsam mit der Trovarit AG Aachen eine Studie durchgeführt, deren Ergebnisse der Beitrag zusammenfasst. Im Fokus standen die Fragen: - Wie weit sind MES-Begriffe potenziellen MES-Anwendern bekannt? - Wie sind MES-Softwarelösungen heute ausgestaltet? - Welchen Nutzen erwarten die Anwender von MES? - Welche logistischen Anforderungen müssen MES-Lösungen bewältigen
Treatment of A549 & SK-MES-1 cells with palbociclib increases expression of MEG3 in a dose-dependent manner.
No full textRelative expression of MEG3 was determined by qPCR in (A) A549 and (B) SK-MES-1 cells treated with increasing concentrations of palbociclib for 48 h. The relative abundance of MEG3 in cells treated with vehicle was set as 1. (C) Representative Western blot demonstrating phospho-Rb and total Rb in A549 and SK-MES-1 cells treated with increasing concentrations of palbociclib for 48 h. (D) Densitometry analysis of the ratio of phosphor-Rb/total Rb from A549 and SK-MES-1 cells treated with increasing concentrations of palbociclib for 48 h. Results are shown as mean ± S.D. for results from at least three independent experiments. *p<0.05.</p
Application of MVVM design pattern in MES
No full textManufacturing Execution System (MES) is developed for information requirement of manufacturing enterprises. Because of different requirement of MES in different enterprises, almost all MES are developed customized. Therefor how to reduce modified codes and decrease the coupling between view page and data become the key for system development. MVVM design model separates software structure to view, model and view model by XAML and Data Binding of WPF technology. The number of modified codes is dramatically reduced because of the using of MVVM design pattern. In this paper, MVVM design pattern for MES development is introduced and MVVM Framework, principle and advantage are also studied in detail
Implantação de um MES (sistema de execução de manufatura) em um ambiente de manufatura enxuta: um estudo de caso em uma linha de montagem de produtos da linha branca
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Mecânica, Florianópolis, 2010Os princípios e as práticas das organizações Lean são reconhecidas no mundo inteiro como a maneira mais eficaz de construir e sustentar a melhoria contínua das empresas, tendo em vista que o mercado global tem exigido das empresas uma eficácia maior e sempre crescente em tudo o que fazem. Melhorar a produtividade, reduzir custos e oferecer produtos de qualidade são fatores vitais para toda e qualquer empresa do mundo. Como a produção em massa está obsoleta no alcance destes objetivos foi necessária uma melhor forma de organizar e gerenciar os relacionamentos com clientes, cadeia de fornecedores, desenvolvimento de produtos e operações de produção, uma abordagem na qual a Toyota foi pioneira após a segunda Guerra Mundial. Essa abordagem é chamada de Manufatura Enxuta (Lean Manufacturing), e trata-se de uma forma de fazer cada vez mais com cada vez menos. Para alcançar os resultados esperados de produtividade e qualidade desejados com a implantação de um Sistema Enxuto de Produção é essencial a existência de um sistema que meça os indicadores do chão de fábrica, tais como OEE (Overall Equipment ffectiveness), tempos de ciclo das máquinas, índice de manutenção, tempos de troca, índice de refugo, produtividade de linhas de montagem, etc e que o mesmo seja a comprovação das melhorias alcançadas e retro-alimente as novas melhorias. Os sistemas que fornecem informações em tempo-real do chão de fábrica são chamados de MES (Manufacturing Execution System). Eles já são amplamente utilizados em fábricas de produção contínua, como indústrias químicas, alimentícias, energéticas, etc, porém, quando falamos de indústrias de produção discreta, especialmente linhas de montagem, os MES são pouco desenvolvidos epouco utilizados. Neste trabalho foi especificado e implementado um sistema MES em linhas de montagem de refrigeradores, voltado à redução de desperdícios utilizando conceitos da Manufatura enxuta. Dentre os ganhos resultantes da implementação do sistema MES, o principal foi o aumento da produtividade. Outros ganhos foram a rastreabilidade de produtos, a confiabilidade dos dados gerados e a adoção do MES como sistema oficial de gestão de linhas de montagem. Trabalhos de melhoria, como projetos de metodologia 6-sigma, passaram a utilizar o MES como fonte de dados e comprovação de ganhos.The principles and practices of Lean organizations are recognized worldwide as the most effective way to build and sustain continuous improvement of companies, considering that the global market has demanded greater and growing efficiency of enterprises in everything they do. Improve productivity, reduce costs and provide quality products are vital factors for any company in the world. As mass production is outdated in reaching these goals, it was necessary a better way to organize and manage customer relationships, supply chain, product development and production operations, an approach in which Toyota has pioneered after the World War II. This approach is called Lean Manufacturing and this is one way of doing more with less. To achieve the expected results of productivity and quality desired by the implementation of a Lean Production System is essential to the existence of a system to measure the key performance indicators of the shop floor, such as OEE (Overall Equipment Effectiveness), cycle times of machines, maintenance index, changeover times, scrap rate, productivity of assembly lines, etc. and that it is proof of the improvements achieved and back-feed the new improvements. The systems which provide real-time shop floor information are called MES (Manufacturing Execution System). They are already widely used in continuous production plants, such as chemical, food, energy, etc. However, when we speak of discrete manufacturing industries, especially assembly lines, the MES are underdeveloped and underutilized. In this research was specified and implemented a MES system in assembly lines of refrigerators, aimed at reducing waste by using concepts of Lean Manufacturing. Among the gains resulting from the implementation of the MES system, the principal was the increase in productivity. Other gains were the traceability of products, the reliability of data generated and the adoption of MES as the official system of management of assembly lines. Improvement projects, such as 6-Sigma methodology bega0n to use the MES as a data source and proof of earnings
Attenuation of reactivity by product solvation: synthesis and molecular structure of [K{(eta(6)-Mes)NC(H)N(Mes)}{(eta(6)-Mes)NHC(H)N(Mes)], the first formamidinate complex of potassium
No full text© Royal Society of Chemistry 2008Ambient temperature treatment of the new bulky formamidine (2,4,6-Me₃C₆H₂)NC(H)NH(2,4,6-Me₃C₆H₂), HFMes, with 0.5 or 1.0 equivalents of potassium hydride or potassium bis(trimethylsilyl)amide yields the first potassium formamidinate complex [K{(η⁶-Mes)NC(H)N(Mes)}{(η⁶-Mes)NHC(H)N(Mes)], which displays attenuated reactivity with respect to deprotonation and solvent replacement of the included HFMes ligand.Jens Baldamus, Christiane Berghof, Marcus L. Cole, David J. Evans, Evamarie Hey-Hawkins and Peter
Lithiation of the diaminopyridine protio-ligand MeC(2-C5H4N){CH2N(H) Mes}(2) (Mes=2,4,6-C6H2Me3)
No full textReaction of the diamidopyridine protio-ligand MeC(2-C5H 4N){CH2N(H)Mes}2 (Mes = 2,4,6-C 6H2Me3) with butyllithium in diethyl ether affords the compound (diethyl ether)(μ4-2-{6-[1,3-dimethyl-3-(2- pyridyl)-1,4-bis(2,4,6-trimethylanilinio)butyl]-2-pyridyl}-2-methyl-1,3-bis(2,4, 6-trimethylanilinio)propane)tetralithium(I), [Li4(C 55H64N6)(C4 H10O)] or Li4[MeC(2-C5H4N){CH2N(Mes)}CHN(2,4, 6-C6H2-Me2C(Me)(2,2′-C5H 3N){C(Me)}(CH2NMes)2](OEt2), which shows the methylation of the pyridyl ortho-position with a methyl group of one of the mesityl groups. The complex contains four Li atoms, each of which is chemically distinct. The tetraanionic ligand contains two protio-ligand units which are fused together into a single entity. The structure contains two disordered molecules of diethyl ether, one of which is coordinated to one of the Li atoms. © 2006 International Union of Crystallography All rights reserved
Activation of H<sub>2</sub> and Et<sub>3</sub>SiH by the Borinium Cation [Mes<sub>2</sub>B]<sup>+</sup>: Avenues to Cations [MesB(μ-H)<sub>2</sub>(μ-Mes)BMes]<sup>+</sup> and [H<sub>2</sub>B(μ-H)(μ-Mes)B(μ-Mes)(μ-H)BH<sub>2</sub>]<sup>+</sup>
No full textReaction
of dihydrogen and the borinium cation salt [Mes2B][B(C6F5)4] gave an arene-stabilized
mesityl-borenium cation, which isotopically scrambles HD. Similarly,
reaction with triethylsilane gave the diboranium cation [MesB(μ-H)2(μ-Mes)BMes]+ featuring three bridge-bonds
between two boron centers. Reaction of same (Mes2BH)2 with Brønsted acid also afforded the same diboranium
whereas the corresponding reaction with (MesBH2)2 yielded the triboron cation [H2B(μ-H)(μ-Mes)B(μ-Mes)(μ-H)BH2]+
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