1,721,022 research outputs found
Effetti patologici causati da chemioterapici antiblastici nei lavoratori addetti alla loro produzione, preparazione o somministrazione.
Confirmation of an excess of cancer mortality in a cohort of workers of a chromium thin-layer plating
Abstract OBJECTIVES: to extend up to year 2013 the follow-up for mortality of a cohort of workers in a chromium and nickel plating plant, where an excess of lung cancers was already identified. DESIGN: 10 years after the first study about cancer mortality in a cohort of workers involved in the chromium thin-layer plating, published in 2006, we updated the evaluation of the mortality of a cohort of workers employed in the same chromiumthin-layer plating factory with at least 6 months of work between 1968 and 1994. The mortality rates are compared with those of the Italian and Veneto Region (Northern Italy) populations. The dose-response relationship between work duration and lung cancer is assessed by adjusted Poisson regression. SETTING AND PARTICIPANTS: 127 unskilled or skilled workers involved in the production process. RESULTS: in the updated follow-up, 35 deaths occurred among the subjects under study: 19 for cancer (of which 11 for lung cancer and 3 for pancreatic cancer). A marked excess ofmortality due to lung cancer is observed. In addition, the new follow-up shows a significant excess of pancreatic cancer mortality. Lung cancer mortality is positively associated with work duration and the risk increases by 13%( 95% CI 1-26) for each additional year of work. CONCLUSIONS: the extension of follow-up confirms that this cohort expresses an increased mortality from cancer deaths, due to a marked excess of lung and pancreatic cancers. The effect of smoking has only a secondary effect in the cancer onset expressed by this cohort. The risk of lung cancer increased with work duration and thus with occupational exposure to chromium and nickel
Confirmation of an excess of cancer mortality in a cohort of workers of a chromium thin-layer plating
OBIETTIVI: valutare il rischio di mortalità fino al 2013 in una coorte di addetti a cromatura a strato sottile in cui era già stata messa in luce la presenza di un eccesso di tumori, in particolare polmonari, dovuta all’esposizione a cromo esavalente e nickel.
DISEGNO: dopo 10 anni dal primo studio sulla mortalità per tumori polmonari tra gli addetti alla cromatura a strato sottile, pubblicato nel 2006, è stata aggiornata la valutazione della mortalità nella coorte degli addetti alla cromatura sottile, già sottoposti ad analisi, con almeno 6 mesi di lavoro nel periodo 1968-1994. Sono calcolati i tassi di mortalità confrontandoli con quelli attesi nella popolazione italiana e del Veneto. E’ stata valutata la relazione doserisposta tra durata del lavoro e insorgenza di tumore del polmone attraverso un modello di regressione di Poisson.
SETTING E PARTECIPANTI: 127 lavoratori con mansione di operaio o impiegato tecnico coinvolti nel processo di produzione.
RISULTATI: tra i 127 soggetti considerati, l’aggiornamento della mortalità al 2013 identifica 35 decessi, dei quali 19 per tumore (di cui 11 per tumore del polmone e 3 per tumore del pancreas). Il confronto con le popolazioni di riferimento conferma il marcato eccesso della mortalità per tumore del polmone. Il nuovo follow-up mette in evidenza anche un eccesso significativo di tumore del pancreas. Il rischio di tumore del polmone è associato alla durata del lavoro, con un aumento del rischio del 13% (IC95% 1-26) per ogni anno di lavoro cumulato.
CONCLUSIONI: l’estensione di 10 anni del follow- up indica che la coorte continua a manifestare un’aumentata frequenza di decessi per tumori, determinata da un eccesso di tumori del polmone e, ora, del pancreas. L’abitudine al fumo di tabacco mostra di avere un effetto secondario nell’insorgenza dei tumori polmonari manifestato dalla coorte. Il rischio di tumore del polmone aumenta al crescere della durata del lavoro, quindi dell’esposizione a cromo e nickel.OBJECTIVES: to extend up to year 2013 the follow-up for mortality of a cohort of workers in a chromium and nickel plating plant, where an excess of lung cancers was already identified. DESIGN: 10 years after the first study about cancer mortality in a cohort of workers involved in the chromium thin-layer plating, published in 2006, we updated the evaluation of the mortality of a cohort of workers employed in the same chromium thin-layer plating factory with at least 6 months of work between 1968 and 1994.The mortality rates are compared with those of the Italian and Veneto Region (Northern Italy) populations.The dose-response relationship between work duration and lung cancer is assessed by adjusted Poisson regression. SETTING AND PARTICIPANTS: 127 unskilled or skilled workers involved in the production process. RESULTS: in the updated follow-up, 35 deaths occurred among the subjects under study: 19 for cancer (of which 11 for lung cancer and 3 for pancreatic cancer). A marked excess of mortality due to lung cancer is observed. In addition, the new follow-up shows a significant excess of pancreatic cancer mortality. Lung cancer mortality is positively associated with work duration and the risk increases by 13% (95%CI 1-26) for each additional year of work. CONCLUSIONS: the extension of follow-up confirms that this cohort expresses an increased mortality from cancer deaths, due to a marked excess of lung and pancreatic cancers.The effect of smoking has only a secondary effect in the cancer onset expressed by this cohort. The risk of lung cancer increased with work duration and thus with occupational exposure to chromium and nickel
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
- …
