172,701 research outputs found
Flavio A. C. Mendonca
No full textDr. Flavio A. C. Mendonca is an assistant professor and researcher in the School of Aviation and Transportation Technology at Purdue University. Prior to entering academics, Dr. Mendonca served 30 years in the Brazilian Air Force as an officer, a pilot, and as an aircraft accident investigator. He has over 30 years of experience as a pilot, with approximately 4,000 flight hours. As a Brazilian Aeronautical Accidents Investigation and Prevention Center member (2001-2007 and 2011-2014), Dr. Mendonca acted in the capacity of Investigator in Charge (IIC) of several aircraft accidents and serious incidents involving Part 121 and Part 135 operators as well as military aircraft.
Dr. Mendonca provided expertise related to aviation safety and the investigation of aircraft accidents and incidents during the ICAO safety management panel, acting as an adviser to the Brazilian team during the development of the first edition of the ICAO Annex 19 – Safety Management. Dr. Mendonca has conducted research studies regarding fatigue identification and management by Part 141 Collegiate Aviation Pilots.
His primary scholarly areas in aviation include aviation safety, fatigue in aviation, human factors, and the safety management of wildlife hazards to aviation.https://commons.erau.edu/ntas-bios/1104/thumbnail.jp
Efeitos de estressores ambientais sobre indicadores fisiológicos, produtivos, de bem-estar e saúde de glândula mamária em vacas leiteiras Girolando.
No full textO presente trabalho teve como objetivo compreender como o estresse por calor em vacas Girolando afeta indicadores fisiológicos, de bem-estar, produção de leite e a resposta celular frente ao desafio com lipopolissacarídeo (LPS) de Escherichia coli imposto à glândula mamária destes animais. A tese foi dividida em três capítulos, sendo o primeiro de revisão sobre o tema. O segundo capítulo trata do estudo que avaliou o efeito isolado do estresse por calor em vacas Girolando. Para tanto, doze vacas em lactação foram submetidas a estresse por calor (HS) por oito horas diárias em câmara climática regulada para manter índice de temperatura e umidade de 85, enquanto as outras doze vacas permaneceram em “free-stall” com sistema de resfriamento (CTR). O terceiro capítulo trata do estudo que avaliou a resposta da glândula mamária destas vacas sob estresse por calor quando desafiados ao LPS. Os mesmos 24 animais do primeiro estudo receberam, no dia 10 do experimento, uma dose única de 100 µg de LPS diluídos em 10 mL de solução fisiológica (0,9% NaCl) no quarto mamário posterior esquerdo e o quarto mamário posterior direito recebeu 10 mL de solução salina 0,9% de NaCl, sendo considerado o quarto mamário controle. A duração dos dois estudos, realizados em sequência, foi de 17 dias. Frequência respiratória (FR), temperatura vaginal (TVag), concentração plasmática de cortisol (CORT), tiroxina (T4), triiodotironina (T3), IGF-1 e insulina (INS), produção de leite, cultivo microbiológico do leite, composição do leite, contagem de células somáticas (CCS), contagem diferencial de células, número de passos e coices, frequência de micção, defecação, ruminação, consumo de matéria-seca e expressão gênica em células do leite foram avaliados. No primeiro estudo, a TVag das vacas HS foi significativamente maior do que as vacas CTR (p0,05). As vacas HS ruminaram menos em sala de ordenha (p0,05). CORT, T4 INS foram significativamente maiores para o grupo HS nas horas 12, 24 e 12 e 24 pós-LPS, respectivamente. Produção de leite não se alterou entre os grupos HS e CTR mas apresentou interação com as horas pós LPS, sendo estatisticamente menor para os dois grupos na hora 24 pós-LPS. Já a CCS também não foi significativamente diferente entre os grupos, mas apresentou elevação significativa em seis horas após o LPS, mantendo-se elevada até 72 horas. A porcentagem de neutrófilos presentes no leite dos quartos mamários tratados com LPS foi significativamente maior do que nos quartos mamários controle nos tempos 6 e 24 horas pós-LPS. A expressão de genes ligados a proteínas de choque térmico, resposta imune e estresse oxidativo foram alteradas. A conclusão geral dos estudos é que as vacas Girolando experienciaram alterações fisiológicas, de comportamento e de produção compatíveis com estresse por calor. Entretanto, este estressor não foi capaz de afetar a imunidade da glândula mamária destes animais nem quando desafiados a um potente indutor de resposta inflamatória como o LPS.Tese (Doutorado em Zootecnia) - Universidade Estadual Paulista, Jaboticabal.
Coorientadora: Wanessa Araújo Carvalho
A MQTT-based infrastructure to support Cooperative Online Learning Activities
No full textTeaching the processes of designing digital electronic systems is becoming an increasingly challenging task. Design methodologies and tools have evolved to cope with the evergrowing complexity and density, raising the abstraction level of the source design far away from the logic circuit. However, it is of paramount importance that fresh students start by understanding the fundamental concepts of Boolean algebra, design, and optimization of combinational and sequential gate-level circuits, before moving to higher abstract concepts and tools. For this, hands-on practice with simple real digital circuits is essential to understanding the essentials of the operation of digital circuits and how digital data is propagated and transformed from block to block. In this paper we present a distributed infrastructure based on the network protocol MQTT to support the deployment of distributed digital systems built with parts located in different physical locations. Thus, promoting the implementation of collaborative online learning/teaching activities will be one of our main goals. Experimental results show latencies between remote sites in the range of a few tens of milliseconds, which is acceptable for running simple digital systems at low speeds, which is necessary for being perceived and understanded by people
Análise econômica de irrigação.
No full textQuanto vale um técnico de extensão rural? Essa pergunta tem me atormentado há muitos anos
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Mitomycin C in highly myopic eyes - Author reply
No full textOphthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
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