1,721,063 research outputs found
Epidemiology of favism, neonatal jaundice and infection-induced jaundice in northern Sardinia
No full textINTERNATIONAL UNION OF ANTHROPOLOGICAL AND ETHNOLOGICAL SCIENCES. INTER-CONGRESS ON BIODEMOGRAPHY AND HUMAN EVOLUTION 1995 FLORENCE, ITALY JULY 3-5, 1995. SYMPOSIUM ON G6PD DEFICIENCY, DIET AND ADAPTATION TO MALARIA.CORTONA ,ITALY APRIL 19-27
Glyburide-induced acute haemolysis in a G6PD-deficient patient with NIDDM
No full textIn a 61-year-old man with glucose-6-phosphate dehydrogenase (G6PD) deficiency and poorly controlled non-insulin-dependent; diabetes mellitus, an episode of acute haemolysis occurred after the administration of glyburide (glibenclamide). Erythrocyte fragmentation, with haemoglobin condensation zones next to clear zones, was observed on peripheral blood smears. Since autoimmune haemolysis was excluded on the basis of laboratory data, acute haemolysis was ascribed to G6PD deficiency
Epidemiology of favism, neonatal jaundice, and infection-induced acute hemolytic anemia in Northern Sardinia
No full text
Marked decline of favism after neonatal glucose-6-phosphate dehydrogenase screening and health education: the Northern Sardinian experience
No full textFavism is a potentially fatal manifestation of glucose-6-phosphate dehydrogenase (G6PD) deficiency, and it is therefore a public health problem in areas where this genetic abnormality is common. In the district of Sassari (northern Sardinia), the frequency of G6PD male hemizygotes is approximately 7.5%, and therefore all newborns since 1971 have been screened for G6PD deficiency. We have analyzed the incidence of favism in this community in two 10-year periods: (1) 1961-1970; and (2) 1981-1990. In period 1, there were 508 cases of favism, of which 76% occurred in boys. In period (2) there were 144 cases of favism, of which only 52% in boys. Thus, between the two periods there was an overall decrease in the incidence of favism of 75%, whereas the proportion of girls affected has approximately doubled. These data suggest that neonatal screening and health education programs can produce a substantial decrease in the number of cases of favism, and that the relative increase in favism in girls is possibly due to failure of the screening method used to detect all the heterozygotes for G6PD deficiency
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