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    Chapter 8.1 Reaction-Diffusion Models of Pattern Formation in Developmental Biology

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    In this paper we present mathematical approaches to understand a symmetry break and formation of spatially heterogenous structures during development. We focus on the models given by reaction-diffusion equations and approach the question of possible mechanisms of development of spatially heterogeneous structures. We discuss two mechanisms of pattern formation: diffusion-driven instability (Turing instability) and a hysteresis-driven mechanism, and demonstrate their possibilities and constraints in explaining different aspects of structure formation in cell systems. Depending on the type of nonlinearities, we show the existence of Turing patterns, the maxima of which may be of the spike or plateau type, and the existence of transition layer stationary solutions. These concepts are discussed on example of morphogenesis of the fresh water polyp Hydra, which is a model organism in developmental biology

    Mathematics and Life Sciences

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    Mathematical Method; Statistical Method; Modeling Method; Life Sciences Applicatio

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Model reduction applied to square to rectangular martensitic transformations using proper orthogonal decomposition

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    Udgivelsesdato: 2007-MayModel reduction using the proper orthogonal decomposition (POD) method is applied to the dynamics of ferroelastic patches to study the first-order square to rectangular phase transformations. Governing equations for the system dynamics are constructed by using the Landau–Ginzburg theory and are solved numerically. By using the POD method, a set of empirical orthogonal basis functions is first constructed, then the system is projected onto the subspace spanned by a small set of basis functions determined by the associated singular values. The performance of the low-dimensional model is verified by simulating nonlinear thermo-mechanical waves and square to rectangular transformations in a ferroelastic patch. Comparison between numerical results obtained from the original PDE model and the low-dimensional one is carried out
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