62 research outputs found
Novel Hybrid Scaffolds for the Cultivation of Osteoblast Cells
No full textTurkoglu Sasmazel, Hilal/0000-0002-0254-4541In this study, natural biodegradable polysaccharide, chitosan, and synthetic biodegradable polymer, poly(epsilon-caprolactone) (PCL) were used to prepare 3D, hybrid polymeric tissue scaffolds (PCL/chitosan blend and PCL/chitosan/PCL layer by layer scaffolds) by using the electrospinning technique. The hybrid scaffolds were developed through HA addition to accelerate osteoblast cell growth. Characteristic examinations of the scaffolds were performed by micrometer, SEM, contact angle measurement system, ATR-FTIR, tensile machine and swelling experiments. The thickness of all electrospun scaffolds was determined in the range of 0.010 +/- 0.001-0.012 +/- 0.002 mm. In order to optimize electrospinning processes, suitable bead-free and uniform scaffolds were selected by using SEM images. Blending of PCL with chitosan resulted in better hydrophilicity for the PCL/chitosan scaffolds. The characteristic peaks of PCL and chitosan in the blend and layer by layer nanofibers were observed. The PCL/chitosan/PCL layer by layer structure had higher elastic modulus and tensile strength values than both individual PCL and chitosan structures. The layer by layer scaffolds exhibited the PBS absorption values of 184.2; 197.2% which were higher than those of PCL scaffolds but lower than those of PCL/chitosan blend scaffolds. SaOs-2 osteosarcoma cell culture studies showed that the highest ALP activities belonged to novel PCL/chitosan/PCL layer by layer scaffolds meaning better cell differentiation on the surfaces. (C) 2011 Elsevier B.V. All rights reserved.Turkish Academy of Science (TUBA) L'Oreal; L'OrealThe author is greatly thankful to Turkish Academy of Science (TUBA) & L'Oreal for honoring this study with the award "Young Women in Science" in Materials Science in 2009. Her special thanks also go to L'Oreal for the precious financial support. The author also appreciates the invaluable contribution of AWAC (Academic Writing Advisory Center) to this study in linguistic terms
Turkish truffles I: 18 new records for Turkey
No full textWOS: 000352486200014We report the first records of 18 truffle species in Turkey. Three belong to the Ascomycota: Elaphomyces leucocarpus, E. muricatus, and Genea sphaerica; and 15 to the Basidiomycota: Alpova corsicus, Gautieria otthii, G. retirugosa, G. trabutii, Hymenogaster citrinus, H. hessei, H. luteus, H. lycoperdineus, Hysterangium clathroides, H. epiroticum, H. fragile, H. nephriticum, Leucogaster tozzianus, Octaviania asterosperma, and Protoglossum aromaticum. We also report new localities within Turkey for Picoa juniperi, P. lefebvrei, Geopora cooperi, Terfezia arenaria, T. claveryi, Tuber aestivum, and T. nitidum in the Ascomycota; and Leucogaster nudus, Hymenogaster thwaitesii, H. vulgaris, and Melanogaster broomeanus in the Basidiomycota.Scientific and Technological Research Council of Turkey projectTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [T-BAG-111T530, BIDEB-2221]The first author received funding from the Scientific and Technological Research Council of Turkey project number T-BAG-111T530 and BIDEB-2221. We appreciate the help from Abdulkadir Simsek, Ahmet Oksuzoglu, Cemhan Bucak, Coskun Bilgi, Duran Celik, Ekrem Toprak, Esra Er, Fatih Kaya, Gulsum Turkoglu, Idris Sener, Kadir Bazlica, Kadir Ceryan, Mehmet Halil Solak, Mehmet Metin, Mehmet Yucel, Murat Kilic, Mustafa Demir, Mustafa Turuncoglu, Niyazi Ulucoban, Okan Kursun, Osman Coban, Serkan Sevinc, Seyit Ahmet Akay, Tolga Keser, Ugur Demirbilek, Veysel Kodalak, and Yavuzalp Turkoglu in the collection of some of the specimens
A nosocomial scabies outbreak originating from immunocompromised transplant patients in Turkey: Upholstery as a possible cause
No full text
High occurrence of cyclosporiasis in Istanbul, Turkey, during a dry and warm summer
No full textAbstract We evaluated the incidence of Cyclospora cayetanensis in immunocompetent, diarrheic patients during the summers of 2006-2009 in Istanbul. Stools from 1876 patients were examined using microscopic techniques. Cyclospora oocysts were observed in wet preparations by light and epifluorescence microscopy and in fecal smears that were stained by Kinyoun's modified acid-fast stain. Characteristic Cyclospora oocysts were observed in 2 patients in 2006, 17 in 2007, and one in 2009. Samples positive for Cyclospora were further analyzed by a single step polymerase chain reaction (PCR) with Cyclospora-specific primers from the ITS-1 region of the genome. The majority of the Cyclospora positive cases (15) were clustered during about 15 days in June 2007, indicating an unusual incidence of cyclosporiasis in this time period. The climatic characteristics of 2007 could have played a role in this high occurrence rate.</p
Comparison Between the Patients Admitted to the Intensive Care Unit with Gastrointestinal Bleeding and the Patients who Had Gastrointestinal Bleeding in the Intensive Care Unit Due to Stress Ulcer
No full textAim: To compare the clinical characteristics, morbidity and mortality of patients admitted to intensive care unit (ICU) with gastrointestinal (GI) bleeding and patients who had new onset GI bleeding in the ICU
Multidrug-resistant Acinetobacter baumannii infection is not an independent risk factor for mortality in critically ill patients with hematologic malignancy
No full textNoninvasive Mechanical Ventilation is Associated with Decreased Mortality in Intensive Care Patients with Chronic Pulmonary Disease
No full textAim: To determine the factors affecting mortality in patients admitted to ICU with chronic pulmonary disease
High occurrence of cyclosporiasis in Istanbul, Turkey, during a dry and warm summer
No full textWe evaluated the incidence of Cyclospora cayetanensis in immunocompetent, diarrheic patients during the summers of 2006-2009 in Istanbul. Stools from 1876 patients were examined using microscopic techniques. Cyclospora oocysts were observed in wet preparations by light and epifluorescence microscopy and in fecal smears that were stained by Kinyoun's modified acid-fast stain. Characteristic Cyclospora oocysts were observed in 2 patients in 2006, 17 in 2007, and one in 2009. Samples positive for Cyclospora were further analyzed by a single step polymerase chain reaction (PCR) with Cyclospora-specific primers from the ITS-1 region of the genome
Cases of OPSI syndrome still candidate for medical ICU
No full textSplenectomized patients are likely to suffer from severe infections, such as sepsis and meningitis, which is called overwhelming postsplenectomy infection (OPSI) syndrome. It seems to be more common in children, but occurs at all ages. The risk is greatest in the early months and years after operation, but never disappears entirely. The course is rapid, the clinical symptoms are serious, and the prognosis is very poor. In this paper, three cases of OPSI syndrome are described, in which infection developed 8, 8 and 15 years after splenectomy; two of the patients died. With the help of these case reports, we want to again emphasize the importance of vaccination, antibiotic prophylaxis and seeking earlier medical attention in splenectomized patients. © 2008 by The Brazilian Journal of Infectious Diseases and Contexto Publishing. All rights reserved
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