235 research outputs found

    What makes for stress or depression among select residents in rural western Wisconsin: namely Barron, Chippewa, Dunn, Pierce, Polk, and St. Croix county's population meeting the 1998 U. S. Department of Health and Services poverty guideline

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    Plan BEach of us encounters daily responsibilities and obligations, along with pressures that challenge are very existence called stress or depression. The purpose of this correlational study was to identify areas of need contributing to, or influencing stress or depression in the impoverished rural western Wisconsin residents. The randomly selected sample group for this study included 785 subjects age eighteen and older living in Barron, Chippewa, Dunn, Pierce, Pepin, Polk, and St. Croix counties. The subjects were selected from the West Central Wisconsin Community Action Agency’s, (West CAP), Client Intake System, (CIS), which included over 3,000 entries from these seven counties. Also, 310 subjects were selected from the Low Income, Housing, and Energy Assistance Program, (LIHEAP), listing in the seven counties. The results obtained by this author include all correlations among the 15 categories contained in this study, yielding a total of 225 inter-correlations. The author has presented an analysis of only those 15 variables, which are directly correlated with stress or depression. The discussion centered on the most critical needs identified which were the need for counseling, and food, and nutrition. The most significant of these need areas is counseling. The Pearson Product Moment Correlation Coefficient identified that all but one of the independent variables correlates with stress or depression. This author concludes that there is a need for additional and more specific research conducted with rural low-income populations. This study leaves question around how poverty level relates to the degree of self-reported stress or depression. Thus, the present study fills a need for information concerning degrees of stress and depression in rural populations

    Improve communication of an autistic child - research into improvement of therapy

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    The author concentrates on the problem of autism defined by most diagnostic classifications as a disturbance in development - it embodies the domain of social and communicative activity. The best known classifications (L. Kanner, M. Rutter, E.R. Ritvo, Diagnostic and Statistic Manual of Mental Disorders - IV) give some information about etiology and methodology in the research of autism. The author pays his attention to the methods of improving communication with autistic children

    Mažai žinomas Klaipėdos ir apylinkių piešinys 1586 m. jūrlapyje | A Sketch of Klaipėda (Memel) and the Surrounding Area in an Unknown Author’s Rutter of 1586

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    By digitising and publicising their exhibits, European archives, libraries and museums are opening up an increasing number of historical sources to a wider audience. This publication deals with a late 16th-century manuscript rutter (a nautical book of sailing directions), created by an unknown Dutch cartographer, and bearing the French title Recveil et povrtraict d’avlcvnes villes maritimes et plvs memorables ports et levrs advenves et marcques servantes a la navigation en la mer oceane. The manuscript is held by the National Library of Spain (Biblioteca Nacional de España) and was thoroughly described by Günter Schilder in 1991. This presentation focuses on two charts out of 24 charts depicting coastlines from La Rochelle to Tallinn in the manuscript that depict the waterways along the shores of the Baltic Sea, the coasts of the Duchy of Courland and Semigallia and the Duchy of Prussia, in a stretch between Memel (Klaipėda) and Danzig (Gdańsk). The drawings show coastlines seen from the sea, as if from a bird’s-eye view, and provide an opportunity to reflect on a view of this stretch of Baltic coast that sailors saw at the time. According to collected data on the depth of the water in the Curonian Lagoon, the author concludes that the drawings present reliable information, probably because they were created based on information provided by sailors. However, the precision of the information is apparently not absolute, as the site 7 Berge (Seven hills), shown between Liepāja and Klaipėda by later sources, was localised here between Ventspils and Liepāja. The charts are also interesting in that they contain a drawing of the town and castle of Memel (Klaipėda) and its surroundings, which was so far not known in the historiography of Klaipėda. It is safe to assume that the 1586 drawings are some of the earliest cartographic sources representing Klaipėda and its surroundings

    Longitudinal patterns of behavioral, emotional, and social difficulties and self-concept in adolescents with a history of specific language impairment

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    Purpose: This study explored the prevalence and stability of behavioral difficulties and self-concepts between 8 and 17 years in a sample of children with a history of specific language impairment (SLI). We investigated whether earlier behavioral, emotional and social difficulties (BESD), self-concepts, language, and literacy abilities predicted behavioral difficulties and self-concepts at 16/17 years. Method: In this prospective longitudinal study, 65 students were followed up with teacher behavior ratings and individual assessments of language, literacy, and self-concepts at 8, 10, 12, 16, and 17 years. Results: The students had consistently higher levels of five domains of BESD, which had different trajectories over time, and poorer scholastic competence, whose trajectory also varied over time. Earlier language ability did not predict later behavioral difficulties or self-concepts but the prediction of academic self-concept at 16 by literacy at 10 years approached significance. Conclusions: We demonstrate the importance of distinguishing domains of behavioral difficulties and self-concept. Language, when measured at 8 or 10 years, was not a predictor of behavior or self-concepts at 16 years, or of self-concepts at 17 years. The study stresses the importance of practitioners addressing academic abilities and different social-behavioral domains in delivering support for adolescents with SLI

    Sarco(endo)plasmic reticulum ATPase is a molecular partner of Wolfram syndrome 1 protein, which negatively regulates its expression.

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    This is a pre-copyedited, author-produced PDF of an article accepted for publication in Human Molecular Genetics following peer review. The version of record Zatyka, M., Xavier, G. D. S., Bellomo, E. A., Leadbeater, W., Astuti, D., Smith, J., Michelangeli, F., Rutter, G. A., Barrett, T. G. (2015). Sarco(endo)plasmic reticulum ATPase is a molecular partner of Wolfram syndrome 1 protein, which negatively regulates its expression. Human Molecular Genetics, 24(3), 814-27 is available online at: http://dx.doi.org/10.1093/hmg/ddu499Wolfram syndrome is an autosomal recessive disorder characterized by neurodegeneration and diabetes mellitus. The gene responsible for the syndrome (WFS1) encodes an endoplasmic reticulum (ER)-resident transmembrane protein that is involved in the regulation of the unfolded protein response (UPR), intracellular ion homeostasis, cyclic adenosine monophosphate production and regulation of insulin biosynthesis and secretion. In this study, single cell Ca(2+) imaging with fura-2 and direct measurements of free cytosolic ATP concentration ([ATP]CYT) with adenovirally expressed luciferase confirmed a reduced and delayed rise in cytosolic free Ca(2+) concentration ([Ca(2+)]CYT), and additionally, diminished [ATP]CYT rises in response to elevated glucose concentrations in WFS1-depleted MIN6 cells. We also observed that sarco(endo)plasmic reticulum ATPase (SERCA) expression was elevated in several WFS1-depleted cell models and primary islets. We demonstrated a novel interaction between WFS1 and SERCA by co-immunoprecipitation in Cos7 cells and with endogenous proteins in human neuroblastoma cells. This interaction was reduced when cells were treated with the ER stress inducer dithiothreitol. Treatment of WFS1-depleted neuroblastoma cells with the proteasome inhibitor MG132 resulted in reduced accumulation of SERCA levels compared with wild-type cells. Together these results reveal a role for WFS1 in the negative regulation of SERCA and provide further insights into the function of WFS1 in calcium homeostasis

    Life histories of burrowing mayflies (Hexagenia limbata and H. rigida, Ephemeroptera: Ephemeridae) in a northern Canadian reservoir

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    1. The life histories and population dynamics of the burrowing mayflies Hexagenia limbata and H. rigida were examined from 1986 to 1988 in four regions of an impounded lake in northern Manitoba, Canada. 2. Bottom temperatures reached 15-20-degrees-C, but ice-free periods of 4-6 months resulted in annual degree day (dd > 10-degrees-C) accumulations of only 210-650 in various regions and years. 3. The life cycles (egg to adult) of both Hexagenia species required 3 yr in the three warmest regions studied and 4 yr in the coolest area; total dd accumulations to complete the life cycle ranged from 1222 to 1468 dd > 10-degrees-C. 4. Fecundity (no. of eggs/female) was strongly correlated to body size of subimagos, and subimago size was strongly correlated to length of nymphal exuviae, so field collection of nymphal exuviae could be used to determine both the size and fecundity of the emerging females. 5. Degree day accumulation in the final year before emergency was a better predictor of emergence timing than overall dd accumulations for the life cycle.PT: J; CR: BRITT NW, 1962, B OHIO BIOL SURVEY, V1, P1 BRITTAIN JE, 1982, ANNU REV ENTOMOL, V27, P19 BURTON W, 1973, J FISH RES BOARD CAN, V30, P287 CARLANDER KD, 1967, ECOLOGY, V48, P873 CLIFFORD HF, 1974, CAN ENTOMOL, V106, P1111 DANKS HV, 1987, BIOL SURVEY CANADA M, V1 EDMUNDS GF, 1976, MAYFLIES N CENTRAL A FLANNAGAN JF, 1979, 2ND P INT C EPH KRAK, P103 FREMLING CR, 1973, 1ST P INT C EPH LEID, P12 GIBERSON DJ, 1991, AMBIO, V20, P139 GIBERSON DJ, 1991, THESIS U MANITOBA WI GIBERSON DJ, 1992, 1837 CAN TECHN REP F GIBERSON DJ, 1992, J N AMER BENTHOL SOC, V11, P181 GIBERSON DJ, 1992, J N AMER BENTHOL SOC, V11, P194 HAMILTON AL, 1974, FISHERIES LIMNOLOG G, V1 HARPER F, 1981, CAN J ZOOL, V59, P1784 HECKY RE, 1984, CAN J FISH AQUAT SCI, V41, P579 HECKY RE, 1984, CAN J FISH AQUAT SCI, V41, P720 HEISE BA, 1987, J N AM BENTHOL SOC, V6, P230 HIGLEY LG, 1986, ENVIRON ENTOMOL, V15, P999 HUDSON PL, 1972, STUDIES NATURAL SCI, V1, P1 HUNT BP, 1951, FLORIDA ENTOMOLOGIST, V34, P59 HUNT BP, 1953, MICHIGAN DEP CONSERV, V4 LYMAN FE, 1944, ENTOMOL NEWS, V55, P207 MCCAFFERTY WP, 1975, T AM ENTOMOL SOC, V101, P447 MCCAFFERTY WP, 1984, ANN ENTOMOL SOC AM, V77, P69 MOZLEY SC, 1988, J GREAT LAKES RES, V14, P171 NEAVE F, 1932, CONTRIBUTIONS CANADI, V7, P177 NEWBURY RW, 1984, CAN J FISH AQUAT SCI, V41, P548 NEWBURY RW, 1984, CANADIAN J FISHERIES, V41, P558 OLIVER DR, 1960, J FISH RES BOARD CAN, V17, P607 PRUESS KP, 1983, ENVIRON ENTOMOL, V12, P613 RAWSON DS, 1953, J FISH RES BOARD CAN, V10, P486 RIKLIK L, 1982, CAN J ZOOL, V60, P2317 RUTTER RP, 1972, THESIS MIAMI U OXFOR SCHLOESSER DW, 1984, J GREAT LAKES RES, V10, P435 SOUTHWOOD TRE, 1978, ECOLOGICAL METHODS STANLEY EH, 1988, OIKOS, V51, P313 SWEENEY BW, 1978, SCIENCE, V200, P444 SWEENEY BW, 1984, ECOLOGY AQUATIC INSE, P56 TAKEMON Y, 1990, MAYFLIES STONEFLIES, P61 TOKESHI M, 1985, J ANIM ECOL, V54, P919 WELCH CL, 1989, HYDROBIOLOGIA, V185, P183 WHELAN KF, 1980, ADV EPHEMEROPTERA BI, P187 WIENS AP, 1984, CAN J FISH AQUAT SCI, V41, P638; NR: 45; TC: 10; J9: FRESHWATER BIOL; PG: 18; GA: PY758Source type: Electronic(1

    SNOWMIP2: An evaluation of forest snow process simulation

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    The Northern Hemisphere has large areas that are forested and seasonally snow covered. Compared with open areas, forest canopies strongly influence interactions between the atmosphere and snow on the ground by sheltering the snow from wind and solar radiation and by intercepting falling snow, and these influences have important consequences for the meteorology, hydrology and ecology of forests. Many of the land surface models used in meteorological and hydrological forecasting now include representations of canopy snow processes, but these have not been widely tested in comparison with observations. Phase 2 of the Snow Model Intercomparison Project (SnowMIP2) was therefore designed as an intercomparison of surface mass and energy balance simulations for snow in forested areas. Model forcing and calibration data for sites with paired forested and open plots were supplied to modelling groups. Participants in 11 countries contributed outputs from 33 models, and results are published here for sites in Canada, the USA and Switzerland. On average, the models perform fairly well in simulating snow accumulation and ablation, although there is a wide inter-model spread and a tendency to underestimate differences in snow mass between open and forested areas. Most models capture the large differences in surface albedos and temperatures between forest canopies and open snow well. There is, however, a strong tendency for models to underestimate soil temperatures under snow, particularly for forest sites, and this would have large consequences for simulations of runoff and biological processes in the soil

    Japanese foreign direct investment : recent trends, determinants, and prospects

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    In the late 1980s, Japan became the biggest source of foreign direct investment (FDI) in the world. The main beneficiaries of the rapid increase in investment flows were industrial countries, but the developing world (especially East Asia and Latin America) also received substantial inflows. In East Asia, the newly industrial economies (NIEs) of Hong Kong, Republic of Korea, Singapore, and Taiwan (China) were, at first, production bases for Japanese manufacturing in the 1970s and early 1980s. But in the late 1980s, these countries became new, expanding consumer markets, attracting huge Japanese investments in the tertiary (service) sector, while investments in manufacturing shrank rapidly because of rising labor costs. The Association of Southeast Nations (ASEAN) and China became Japan's new production base. In Latin America (mostly small Caribbean countries) Japan's focus is almost exclusively on tax havens. Globally, Japan's investments in the secondary (manufacturing) and service sectors of the major Latin American nations are only marginal. Japanese investment flows declined drastically after 1989, mostly because of the depressed global and domestic economy, after rapid asset price deflation in Japan. Hardest hit by the decline were the United States and Europe. Japanese FDI flows to developing countries also declined, but less. The biggest losers were the NIEs and the Caribbean tax havens. The biggest losers were the NIEs and the Caribbean tax havens. Japanese investments continued to grow in other Latin American countries and, even more, in the ASEAN and China. Japanese investors sharply reduced tertiary sector investments, primarily geared to maintaining or expanding markets. Investments in the secondary sector, making use of low-cost production, continued to expand. This trend is expected to continue in the near future, with FDI flows declining further, albeit more slowly. Low-wage production countries such as China and Indonesia will attract an increasing share. Investment to expand markets in the industrial countries and the NIEs are likely to decline. But medium-term prospects for Japanese FDI in developing countries are brighter, as economic recovery and continuing current account surpluses in Japan will lead to a resumption of active foreign investment by Japanese multinational corporations.Foreign Direct Investment,Environmental Economics&Policies,International Terrorism&Counterterrorism,Economic Theory&Research,Trade and Regional Integration
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